IN2014DN08984A - - Google Patents

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Publication number
IN2014DN08984A
IN2014DN08984A IN8984DEN2014A IN2014DN08984A IN 2014DN08984 A IN2014DN08984 A IN 2014DN08984A IN 8984DEN2014 A IN8984DEN2014 A IN 8984DEN2014A IN 2014DN08984 A IN2014DN08984 A IN 2014DN08984A
Authority
IN
India
Prior art keywords
pro
lys
gly
thr
arg
Prior art date
Application number
Inventor
Nikolay Fedorovich Myasoedov
Lyudmila Alexandrovna Andreeva
Dmitriy Viktorovich Golikov
Original Assignee
Obshchestvo S Ogranichennoy Otvetstvennostiyu Ivix
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Obshchestvo S Ogranichennoy Otvetstvennostiyu Ivix filed Critical Obshchestvo S Ogranichennoy Otvetstvennostiyu Ivix
Publication of IN2014DN08984A publication Critical patent/IN2014DN08984A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1005Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention relates to biochemistry and biotechnology and is directed to producing peptides with sex- and sexual- fimction-stimulating activity of general formula: A-Thr-Lys-Pro-B-C-D-X, where A is 0, Met, Met(0), Thr, Ala, His, Phe, Lys, ARG PRO GL PRO Gly, В is 0, Gly, Asp, Trp, Gin, Asn, Tyr, BOс -он H - Pro, Arg, С is 0, Arg, Phe, Tyr, Gly, His, BOC- Pro, Lys, D is 0, Val, Gly, Tyr, Trp, Phe, His, X is OH, OCH3, NH , where 0 is the ab- B C- 3 H- - Bzl sence of an amino acid residue, under the BO C- OBzl condition that, if A^0, then В and/or С and/or D ), and if B ), then С and/or D ), O H- OBzl excluding the peptides Phe-Thr-Lys-Pro- N0 BOC OBzl Gly, Thr-Lys-Pro-Pro-Arg, Thr-Lys-Pro- < O, VI Arg-Gly. The invention is also directed to a BOC H method for producing the peptides men- H- -OH tioned by genetic engineering methods.
IN8984DEN2014 2012-03-28 2013-05-28 IN2014DN08984A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2012111965A RU2507212C3 (en) 2012-03-28 2012-03-28 METHOD FOR PRODUCING RECOMBINANT PEPTIDE AND PRODUCED PEPTIDE
PCT/RU2013/000433 WO2013151467A2 (en) 2012-03-28 2013-05-28 Method for producing a recombinant peptide and resultant peptide

Publications (1)

Publication Number Publication Date
IN2014DN08984A true IN2014DN08984A (en) 2015-05-22

Family

ID=49301137

Family Applications (1)

Application Number Title Priority Date Filing Date
IN8984DEN2014 IN2014DN08984A (en) 2012-03-28 2013-05-28

Country Status (12)

Country Link
US (2) US9409947B2 (en)
EP (2) EP2876113B1 (en)
BR (1) BR112014023888B1 (en)
CA (1) CA2868820C (en)
DK (1) DK2876113T3 (en)
ES (1) ES2768300T3 (en)
IL (1) IL234753B (en)
IN (1) IN2014DN08984A (en)
PL (1) PL2876113T3 (en)
PT (1) PT2876113T (en)
RU (1) RU2507212C3 (en)
WO (1) WO2013151467A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2507212C3 (en) * 2012-03-28 2022-05-04 Общество С Ограниченной Ответственностью "Айвикс" METHOD FOR PRODUCING RECOMBINANT PEPTIDE AND PRODUCED PEPTIDE
RU2655763C2 (en) * 2016-10-24 2018-05-29 Общество С Ограниченной Ответственностью "Айвикс" Pharmaceutical composition and method for treating female sexual dysfunctions
RU2626002C1 (en) 2016-10-24 2017-07-21 Общество С Ограниченной Ответственностью "Айвикс" New group of peptides for treatment of female sexual dysfunction
RU2709503C1 (en) * 2019-05-23 2019-12-18 Акционерное общество "Инновационный научно-производственный центр "Пептоген" (АО "ИНПЦ "Пептоген") USE OF THE PEPTIDE Thr-Lys-Pro-Arg-Pro-Gly-Pro (SELANK) TO INCREASE BODY RESISTANCE TO ACUTE HYPOTHERMIA

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3778426A (en) * 1970-12-16 1973-12-11 Research Corp Therapeutically useful polypeptides
RU1124544C (en) * 1983-06-30 1995-01-09 Институт молекулярной генетики РАН Heptapeptide possessing properties of psychostimulator of prolonged action with immunotropic activity
RU2058791C1 (en) 1989-01-11 1996-04-27 Государственное предприятие "Элер-микро" Stimulating agent of reproductive capability in warm-blooded animal
US5872100A (en) 1990-05-11 1999-02-16 Deghenghi; Romano Peptides containing D-2-Alkyl-Tryptophan
DE69429768T2 (en) 1993-04-05 2002-09-19 Competitive Technologies, Inc. DIAGNOSIS AND TREATMENT OF ERECTILE FUNCTIONAL FAULTS
US5932548A (en) 1998-06-03 1999-08-03 Deghenghi; Romano Lysine containing peptides for treatment of heart disease
RU2155065C1 (en) 1999-04-23 2000-08-27 Институт молекулярной генетики РАН Anxiolytic agent and pharmaceutical composition with anxiolytic effect
US6211156B1 (en) 1999-11-10 2001-04-03 Asta Medica A.G. Peptides for treatment of erectile dysfunction
RU2252779C1 (en) 2003-09-23 2005-05-27 Институт Молекулярной Генетики Российской Академии Наук (Имг Ран) Method for preventing and treating ulcers of gastro-intestinal tract
RU2290195C1 (en) 2005-04-21 2006-12-27 Институт Молекулярной Генетики Российской Академии Наук (Имг Ран) Agent possessing anti-coagulating, anti-thrombocytic, anti-thrombosis, fibrin-depolymerizing and fibrinolytic activity
CN101302246B (en) 2007-05-09 2011-05-11 中国人民解放军军事医学科学院毒物药物研究所 Melanin cortical hormone receptor heptapeptide excitant, preparation and use thereof
WO2009033792A2 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Gamma 1 msh alone or in combination with pentagastrin as a therapeutic agent
US7618801B2 (en) 2007-10-30 2009-11-17 Danison US Inc. Streptomyces protease
RU2411249C2 (en) * 2008-12-11 2011-02-10 Учреждение Российской академии наук Институт молекулярной генетики РАН (ИМГ РАН) Agent for viruses: encephalomyocarditis, influenza type a, herpes simplex type 2
RU2404793C1 (en) 2009-06-04 2010-11-27 Общество с ограниченной ответственностью Био Пептид Stimulator of genital, sexual and reproductive function
EA200900804A1 (en) * 2009-06-08 2010-08-30 Общество С Ограниченной Ответственностью "Витанта" MEANS ACTIVATING SEXUAL FUNCTION
RU2507212C3 (en) * 2012-03-28 2022-05-04 Общество С Ограниченной Ответственностью "Айвикс" METHOD FOR PRODUCING RECOMBINANT PEPTIDE AND PRODUCED PEPTIDE

Also Published As

Publication number Publication date
WO2013151467A3 (en) 2014-01-09
BR112014023888B1 (en) 2021-12-07
ES2768300T3 (en) 2020-06-22
RU2012111965A (en) 2013-10-10
EP3650457A1 (en) 2020-05-13
PL2876113T3 (en) 2020-06-15
EP3650457B1 (en) 2021-03-17
CA2868820A1 (en) 2013-10-10
BR112014023888A2 (en) 2018-05-29
US20170158735A1 (en) 2017-06-08
EP2876113A4 (en) 2017-03-01
RU2507212C2 (en) 2014-02-20
RU2507212C3 (en) 2022-05-04
EP2876113A2 (en) 2015-05-27
US9409947B2 (en) 2016-08-09
WO2013151467A2 (en) 2013-10-10
DK2876113T3 (en) 2020-02-03
PT2876113T (en) 2020-02-03
IL234753B (en) 2018-11-29
EP2876113B1 (en) 2019-11-06
US20150111837A1 (en) 2015-04-23
CA2868820C (en) 2021-09-21

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