IN2014DN08135A - - Google Patents
Info
- Publication number
- IN2014DN08135A IN2014DN08135A IN8135DEN2014A IN2014DN08135A IN 2014DN08135 A IN2014DN08135 A IN 2014DN08135A IN 8135DEN2014 A IN8135DEN2014 A IN 8135DEN2014A IN 2014DN08135 A IN2014DN08135 A IN 2014DN08135A
- Authority
- IN
- India
- Prior art keywords
- reaction sites
- chip
- biological reactions
- nanoliter
- substrate
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B01L3/50857—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates using arrays or bundles of open capillaries for holding samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B01L3/50851—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- G—PHYSICS
- G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
- G03F—PHOTOMECHANICAL PRODUCTION OF TEXTURED OR PATTERNED SURFACES, e.g. FOR PRINTING, FOR PROCESSING OF SEMICONDUCTOR DEVICES; MATERIALS THEREFOR; ORIGINALS THEREFOR; APPARATUS SPECIALLY ADAPTED THEREFOR
- G03F7/00—Photomechanical, e.g. photolithographic, production of textured or patterned surfaces, e.g. printing surfaces; Materials therefor, e.g. comprising photoresists; Apparatus specially adapted therefor
- G03F7/20—Exposure; Apparatus therefor
- G03F7/2002—Exposure; Apparatus therefor with visible light or UV light, through an original having an opaque pattern on a transparent support, e.g. film printing, projection printing; by reflection of visible or UV light from an original such as a printed image
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0642—Filling fluids into wells by specific techniques
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/142—Preventing evaporation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0654—Lenses; Optical fibres
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0829—Multi-well plates; Microtitration plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0893—Geometry, shape and general structure having a very large number of wells, microfabricated wells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0896—Nanoscaled
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/16—Surface properties and coatings
- B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Clinical Laboratory Science (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Optical Measuring Cells (AREA)
- Sampling And Sample Adjustment (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
A system for performing biological reactions is provided. The system includes a chip including a substrate and a plurality of reaction sites. The plurality of reaction sites are each configured to include a liquid sample of at most one nanoliter. Further the system includes a control system configured to initiate biological reactions within the liquid samples. The system further includes a detection system configured to detect biological reactions on the chip. According to various embodiments the chip includes at least 20000 reaction sites. In other embodiments the chip includes at least 30000 reaction sites.
Applications Claiming Priority (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261612087P | 2012-03-16 | 2012-03-16 | |
US201261612005P | 2012-03-16 | 2012-03-16 | |
US201261612008P | 2012-03-16 | 2012-03-16 | |
US201261659029P | 2012-06-13 | 2012-06-13 | |
US201261723738P | 2012-11-07 | 2012-11-07 | |
US201261723658P | 2012-11-07 | 2012-11-07 | |
US201261723710P | 2012-11-07 | 2012-11-07 | |
US201261723759P | 2012-11-07 | 2012-11-07 | |
US201361774499P | 2013-03-07 | 2013-03-07 | |
PCT/US2013/032420 WO2013138767A1 (en) | 2012-03-16 | 2013-03-15 | Systems and methods for biological analysis |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014DN08135A true IN2014DN08135A (en) | 2015-05-01 |
Family
ID=48014371
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN8135DEN2014 IN2014DN08135A (en) | 2012-03-16 | 2013-03-15 |
Country Status (10)
Country | Link |
---|---|
US (4) | US20150080247A1 (en) |
EP (2) | EP2825310A2 (en) |
JP (2) | JP2015511015A (en) |
KR (2) | KR20140140080A (en) |
CN (2) | CN104302400B (en) |
AU (1) | AU2013231910A1 (en) |
IN (1) | IN2014DN08135A (en) |
RU (2) | RU2014140837A (en) |
SG (2) | SG11201405785WA (en) |
WO (2) | WO2013138706A2 (en) |
Families Citing this family (21)
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DE102012100824A1 (en) * | 2012-02-01 | 2013-09-05 | Albert-Ludwigs-Universität Freiburg | Multiplexed Digital PCR |
SG11201510642UA (en) | 2013-05-24 | 2016-02-26 | Life Technologies Corp | Case and case holder for biological samples and corresponding method of use |
WO2015173651A1 (en) * | 2014-05-14 | 2015-11-19 | Mark Davies | Microfluidic device with channel plates |
KR102494654B1 (en) | 2015-02-06 | 2023-01-31 | 라이프 테크놀로지스 코포레이션 | Biological sample evaluation systems and methods |
JP6661947B2 (en) * | 2015-10-01 | 2020-03-11 | 凸版印刷株式会社 | Fluorescent image capturing apparatus and fluorescent image capturing method |
CN105543064B (en) * | 2015-12-29 | 2018-04-17 | 西安交通大学 | A kind of digital pcr chip and its application method |
JP6824290B2 (en) | 2016-05-18 | 2021-02-03 | イルミナ インコーポレイテッド | Self-assembled patterning with a patterned hydrophobic surface |
US11719702B2 (en) | 2016-11-07 | 2023-08-08 | Battelle Memorial Institute | Methods and systems of proteome analysis and imaging |
EP3535418B1 (en) * | 2016-11-07 | 2021-12-15 | Battelle Memorial Institute | Nanoscale biochemical sample preparation and analysis |
CA3046827A1 (en) | 2016-12-12 | 2018-06-21 | xCella Biosciences, Inc. | Methods and systems for screening using microcapillary arrays |
US11085039B2 (en) | 2016-12-12 | 2021-08-10 | xCella Biosciences, Inc. | Methods and systems for screening using microcapillary arrays |
AU2017388058B2 (en) | 2016-12-30 | 2023-02-02 | xCella Biosciences, Inc. | Multi-stage sample recovery system |
CN107254511A (en) * | 2017-04-27 | 2017-10-17 | 臻准生物科技(上海)有限公司 | A kind of digital pcr chip signal read method |
CN111349555B (en) * | 2018-12-21 | 2023-07-18 | 成都万众壹芯生物科技有限公司 | Digital PCR amplification device based on micropore array chip and use method thereof |
JP7347931B2 (en) * | 2018-12-26 | 2023-09-20 | スリーエム イノベイティブ プロパティズ カンパニー | Film for microfluidic device, microfluidic device and manufacturing method thereof |
JP6912140B2 (en) * | 2019-03-28 | 2021-07-28 | 国立大学法人愛媛大学 | Spectral analysis chip |
CN112239719A (en) * | 2019-07-19 | 2021-01-19 | 成都万众壹芯生物科技有限公司 | Digital PCR amplification device based on micropore array chip and method for amplifying by using same |
US20220091065A1 (en) * | 2020-09-18 | 2022-03-24 | Visera Technologies Company Limited | Sensor device and method of using the same |
KR102595551B1 (en) * | 2021-06-23 | 2023-10-30 | (주)옵토레인 | Diagnostic chip having a multi-hydrophilic function |
KR20230009244A (en) * | 2021-07-08 | 2023-01-17 | (주)옵토레인 | Pcr module |
KR20230138571A (en) * | 2022-03-23 | 2023-10-05 | 삼성전자주식회사 | Apparatus and method for bio-particle detection |
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CN102869630A (en) * | 2010-02-10 | 2013-01-09 | 生命生物科学有限公司 | Methods to fabricate a photoactive substrate suitable for microfabrication |
JP2015511016A (en) * | 2012-03-16 | 2015-04-13 | ライフ テクノロジーズ コーポレーション | System and method for filling a liquid sample |
-
2013
- 2013-03-15 RU RU2014140837A patent/RU2014140837A/en not_active Application Discontinuation
- 2013-03-15 JP JP2015500646A patent/JP2015511015A/en active Pending
- 2013-03-15 SG SG11201405785WA patent/SG11201405785WA/en unknown
- 2013-03-15 KR KR20147029044A patent/KR20140140080A/en not_active Application Discontinuation
- 2013-03-15 WO PCT/US2013/032002 patent/WO2013138706A2/en active Application Filing
- 2013-03-15 IN IN8135DEN2014 patent/IN2014DN08135A/en unknown
- 2013-03-15 WO PCT/US2013/032420 patent/WO2013138767A1/en active Application Filing
- 2013-03-15 EP EP13713043.1A patent/EP2825310A2/en not_active Withdrawn
- 2013-03-15 US US14/385,730 patent/US20150080247A1/en not_active Abandoned
- 2013-03-15 US US14/385,765 patent/US20150044686A1/en not_active Abandoned
- 2013-03-15 KR KR20147028892A patent/KR20150003738A/en not_active Application Discontinuation
- 2013-03-15 CN CN201380025569.7A patent/CN104302400B/en active Active
- 2013-03-15 AU AU2013231910A patent/AU2013231910A1/en not_active Abandoned
- 2013-03-15 EP EP13713049.8A patent/EP2825314A1/en not_active Withdrawn
- 2013-03-15 RU RU2014141637A patent/RU2014141637A/en not_active Application Discontinuation
- 2013-03-15 CN CN201380022560.0A patent/CN104411408B/en active Active
- 2013-03-15 SG SG11201406039WA patent/SG11201406039WA/en unknown
- 2013-03-15 JP JP2015500667A patent/JP2015516802A/en active Pending
-
2019
- 2019-05-30 US US16/426,631 patent/US11590506B2/en active Active
-
2022
- 2022-12-21 US US18/086,416 patent/US20230201839A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP2825314A1 (en) | 2015-01-21 |
CN104302400B (en) | 2017-03-01 |
SG11201406039WA (en) | 2014-11-27 |
US20150080247A1 (en) | 2015-03-19 |
WO2013138706A2 (en) | 2013-09-19 |
US20150044686A1 (en) | 2015-02-12 |
CN104302400A (en) | 2015-01-21 |
WO2013138706A3 (en) | 2014-01-16 |
US11590506B2 (en) | 2023-02-28 |
AU2013231910A1 (en) | 2014-10-30 |
JP2015511015A (en) | 2015-04-13 |
CN104411408A (en) | 2015-03-11 |
CN104411408B (en) | 2017-07-11 |
US20190381502A1 (en) | 2019-12-19 |
RU2014141637A (en) | 2016-05-10 |
US20230201839A1 (en) | 2023-06-29 |
WO2013138767A1 (en) | 2013-09-19 |
EP2825310A2 (en) | 2015-01-21 |
KR20140140080A (en) | 2014-12-08 |
KR20150003738A (en) | 2015-01-09 |
RU2014140837A (en) | 2016-05-10 |
SG11201405785WA (en) | 2014-11-27 |
JP2015516802A (en) | 2015-06-18 |
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