IN2014DN07509A - - Google Patents
Info
- Publication number
- IN2014DN07509A IN2014DN07509A IN7509DEN2014A IN2014DN07509A IN 2014DN07509 A IN2014DN07509 A IN 2014DN07509A IN 7509DEN2014 A IN7509DEN2014 A IN 7509DEN2014A IN 2014DN07509 A IN2014DN07509 A IN 2014DN07509A
- Authority
- IN
- India
- Prior art keywords
- independently
- optionally substituted
- therapy
- halogen
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1204125.7A GB201204125D0 (en) | 2012-03-08 | 2012-03-08 | Compounds |
PCT/GB2013/050583 WO2013132270A1 (en) | 2012-03-08 | 2013-03-08 | Phosphoinositide 3-kinase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014DN07509A true IN2014DN07509A (hr) | 2015-04-24 |
Family
ID=46026238
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN7509DEN2014 IN2014DN07509A (hr) | 2012-03-08 | 2013-03-08 |
Country Status (6)
Country | Link |
---|---|
US (2) | US9663487B2 (hr) |
EP (1) | EP2822943B1 (hr) |
CN (1) | CN104254532A (hr) |
GB (1) | GB201204125D0 (hr) |
IN (1) | IN2014DN07509A (hr) |
WO (1) | WO2013132270A1 (hr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR112012003955A2 (pt) | 2009-08-20 | 2017-09-26 | Karus Therapeutics Ltd | compostos heterocíclicos tricíclicos como inibidores da fosfoinositídeos 3-quinase |
GB201204125D0 (en) | 2012-03-08 | 2012-04-25 | Karus Therapeutics Ltd | Compounds |
IN2015DN03235A (hr) | 2012-11-07 | 2015-10-02 | Karus Therapeutics Ltd | |
EP2916868B1 (en) | 2012-11-08 | 2022-05-11 | Rhizen Pharmaceuticals S.A. | Pharmaceutical compositions containing a pde4 inhibitor and a pi3 delta or dual pi3 delta-gamma kinase inhibitor |
RS57816B1 (sr) | 2013-05-10 | 2018-12-31 | Karus Therapeutics Ltd | Inhibitori histon deacetilaze |
GB201402431D0 (en) | 2014-02-12 | 2014-03-26 | Karus Therapeutics Ltd | Compounds |
GB201419264D0 (en) | 2014-10-29 | 2014-12-10 | Karus Therapeutics Ltd | Compounds |
GB201419228D0 (en) | 2014-10-29 | 2014-12-10 | Karus Therapeutics Ltd | Compounds |
GB201514751D0 (en) | 2015-08-19 | 2015-09-30 | Karus Therapeutics Ltd | Compounds |
GB201514760D0 (en) | 2015-08-19 | 2015-09-30 | Karus Therapeutics Ltd | Compounds and method of use |
GB201514754D0 (en) | 2015-08-19 | 2015-09-30 | Karus Therapeutics Ltd | Compounds |
GB201514758D0 (en) | 2015-08-19 | 2015-09-30 | Karus Therapeutics Ltd | Formulation |
TW201940483A (zh) | 2018-03-12 | 2019-10-16 | 美商艾伯維有限公司 | 酪胺酸激酶2介導的傳訊之抑制劑 |
Family Cites Families (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1445742A1 (de) | 1963-11-06 | 1968-12-19 | Bayer Ag | Verfahren zur Herstellung von 2-Stellung substituierten Benzoxazinonen |
US4017500A (en) | 1973-07-16 | 1977-04-12 | Schering Corporation | Certain 8-amino-1,7-naphthyridines |
US5703075A (en) | 1988-12-21 | 1997-12-30 | Pharmacia & Upjohn Company | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones |
CN100345830C (zh) | 2000-04-27 | 2007-10-31 | 安斯泰来制药有限公司 | 稠合杂芳基衍生物 |
US6608053B2 (en) | 2000-04-27 | 2003-08-19 | Yamanouchi Pharmaceutical Co., Ltd. | Fused heteroaryl derivatives |
EP1296975A1 (en) * | 2000-06-30 | 2003-04-02 | Sugen, Inc. | 4-heteroaryl-3-heteroarylidenyl-2-indolinones and their use as protein kinase inhibitors |
US6905669B2 (en) | 2001-04-24 | 2005-06-14 | Supergen, Inc. | Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase |
CA2491191C (en) | 2002-07-15 | 2014-02-04 | Exelixis, Inc. | Receptor-type kinase modulators and methods of use |
FR2846657B1 (fr) | 2002-11-05 | 2004-12-24 | Servier Lab | Nouveaux composes pyridopyrimidinone, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
JP4912145B2 (ja) | 2004-02-26 | 2012-04-11 | あすか製薬株式会社 | ピリミジン誘導体 |
GB0423653D0 (en) | 2004-10-25 | 2004-11-24 | Piramed Ltd | Pharmaceutical compounds |
CA2609126A1 (en) | 2005-05-20 | 2006-11-30 | Vertex Pharmaceuticals Incorporated | Pyrrolopyridines useful as inhibitors of protein kinase |
US20070208053A1 (en) * | 2006-01-19 | 2007-09-06 | Arnold Lee D | Fused heterobicyclic kinase inhibitors |
US8252792B2 (en) | 2006-04-26 | 2012-08-28 | F. Hoffman-La Roche Ag | Pyrimidine derivatives as PI3K inhibitors |
MX2008013583A (es) | 2006-04-26 | 2008-10-31 | Genentech Inc | Compuestos del inhibidor de fosfoinositido 3-cinasa y composiciones farmaceuticas que los contienen. |
EP2441768A1 (en) | 2006-11-13 | 2012-04-18 | Eli Lilly & Co. | Thienopyrimidinones for treatment of inflammatory disorders and cancers |
JP2010518014A (ja) * | 2007-01-31 | 2010-05-27 | バーテックス ファーマシューティカルズ インコーポレイテッド | キナーゼ阻害剤として有用な2−アミノピリジン誘導体 |
CN101663276A (zh) * | 2007-01-31 | 2010-03-03 | 沃泰克斯药物股份有限公司 | 用作激酶抑制剂的2-氨基吡啶衍生物 |
US20100063032A1 (en) | 2007-03-28 | 2010-03-11 | Debenham John S | Substituted pyrido[2,3-d]pyrimidine derivatives as cannabinoid-1 receptor modulators |
US20100179143A1 (en) | 2007-05-29 | 2010-07-15 | Smithkline Beecham Corporation | Naphthyridine, derivatives as p13 kinase inhibitors |
GB0710528D0 (en) * | 2007-06-01 | 2007-07-11 | Glaxo Group Ltd | Novel compounds |
WO2010015520A1 (de) | 2008-08-05 | 2010-02-11 | Boehringer Ingelheim International Gmbh | Substituierte naphthyridine und ihre verwendung als arzneimittel |
US20110257170A1 (en) | 2008-10-03 | 2011-10-20 | Merck Serono Sa | 4-morpholino-pyrido[3,2-d]pyrimidines |
GB2465405A (en) | 2008-11-10 | 2010-05-19 | Univ Basel | Triazine, pyrimidine and pyridine analogues and their use in therapy |
WO2011012883A1 (en) | 2009-07-29 | 2011-02-03 | Karus Therapeutics Limited | Benzo [e] [1, 3 ] oxazin-4-one derivatives as phosphoinositide 3-kinase inhibitors |
BR112012003955A2 (pt) | 2009-08-20 | 2017-09-26 | Karus Therapeutics Ltd | compostos heterocíclicos tricíclicos como inibidores da fosfoinositídeos 3-quinase |
US20110207736A1 (en) | 2009-12-23 | 2011-08-25 | Gatekeeper Pharmaceuticals, Inc. | Compounds that modulate egfr activity and methods for treating or preventing conditions therewith |
GB201007347D0 (en) | 2010-04-30 | 2010-06-16 | Karus Therapeutics Ltd | Compounds |
WO2013014448A1 (en) | 2011-07-27 | 2013-01-31 | Astrazeneca Ab | 2 - (2, 4, 5 - substituted -anilino) pyrimidine derivatives as egfr modulators useful for treating cancer |
WO2013017480A1 (en) | 2011-07-29 | 2013-02-07 | Cellzome Limited | Pyrazolo[4,3-c]pyridine derivatives as jak inhibitors |
GB201204125D0 (en) | 2012-03-08 | 2012-04-25 | Karus Therapeutics Ltd | Compounds |
WO2014081718A1 (en) | 2012-11-20 | 2014-05-30 | Genentech, Inc. | Aminopyrimidine compounds as inhibitors of t790m containing egfr mutants |
RS57816B1 (sr) | 2013-05-10 | 2018-12-31 | Karus Therapeutics Ltd | Inhibitori histon deacetilaze |
EP3052494B1 (en) | 2013-06-28 | 2018-12-26 | H. Hoffnabb-La Roche Ag | Azaindazole compounds as inhibitors of t790m containing egfr mutants |
US20150105383A1 (en) | 2013-10-10 | 2015-04-16 | Acetylon Pharmaceuticals, Inc. | HDAC Inhibitors, Alone Or In Combination With PI3K Inhibitors, For Treating Non-Hodgkin's Lymphoma |
GB201402431D0 (en) | 2014-02-12 | 2014-03-26 | Karus Therapeutics Ltd | Compounds |
GB201514751D0 (en) | 2015-08-19 | 2015-09-30 | Karus Therapeutics Ltd | Compounds |
GB201514758D0 (en) | 2015-08-19 | 2015-09-30 | Karus Therapeutics Ltd | Formulation |
GB201514754D0 (en) | 2015-08-19 | 2015-09-30 | Karus Therapeutics Ltd | Compounds |
GB201514756D0 (en) | 2015-08-19 | 2015-09-30 | Karus Therapeutics Ltd | Compound and method of use |
GB201514760D0 (en) | 2015-08-19 | 2015-09-30 | Karus Therapeutics Ltd | Compounds and method of use |
-
2012
- 2012-03-08 GB GBGB1204125.7A patent/GB201204125D0/en not_active Ceased
-
2013
- 2013-03-08 IN IN7509DEN2014 patent/IN2014DN07509A/en unknown
- 2013-03-08 US US14/382,196 patent/US9663487B2/en not_active Expired - Fee Related
- 2013-03-08 EP EP13709523.8A patent/EP2822943B1/en not_active Not-in-force
- 2013-03-08 CN CN201380013216.5A patent/CN104254532A/zh active Pending
- 2013-03-08 WO PCT/GB2013/050583 patent/WO2013132270A1/en active Application Filing
-
2017
- 2017-04-25 US US15/496,511 patent/US10035785B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO2013132270A1 (en) | 2013-09-12 |
US20150080395A1 (en) | 2015-03-19 |
GB201204125D0 (en) | 2012-04-25 |
EP2822943B1 (en) | 2018-10-03 |
US10035785B2 (en) | 2018-07-31 |
US20180072699A1 (en) | 2018-03-15 |
US9663487B2 (en) | 2017-05-30 |
CN104254532A (zh) | 2014-12-31 |
EP2822943A1 (en) | 2015-01-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IN2014DN07509A (hr) | ||
MX2016006336A (es) | Compuestos pirazolopirimidina. | |
SA515360469B1 (ar) | مركبات حلقية غير متجانسة لتثبيط إنزيم جلوتاميناز والطرق الخاصة باستخدامها | |
TN2012000401A1 (en) | Heterocyclic compound | |
NZ705705A (en) | Ret inhibitor | |
PH12014501719A1 (en) | Pyridone derivatives | |
MX344025B (es) | Inhibidores de proteínas quinasas. | |
GEP201606532B (en) | Benzamide derivatives for inhibiting the activity of abl1, abl2 and bcr-abl1 | |
IN2014MN02598A (hr) | ||
UA108926C2 (ru) | LibreOffice? [2,3-D] +" +" !+ | |
MY193277A (en) | Certain amino-pyrimidines, compositions thereof, and methods for their use | |
MY180618A (en) | Pyridazinone compounds and their use as daao inhibitors | |
RS54526B1 (en) | USE OF PIRAZOLOSPIROKETONE DERIVATIVES AS ACETYL-COA CARBOXYLASE INHIBITORS | |
MY186599A (en) | Substituted pyridopyrazines as novel syk inhibitors | |
MY172422A (en) | Pyrazole compound and pharmaceutical use thereof | |
GB201209587D0 (en) | Therapeutic compounds | |
PH12015502429A1 (en) | Dicarboxylic acid compound | |
MX2013005819A (es) | Benzoxazepinas como inhibidores de 3-cinasa/objetivo mamífero de rapamicina (pi3k/mtor) metodos de uso y fabricacion. | |
MX2014015345A (es) | Inhibidores piranopiridona de tanquirasa. | |
MX359399B (es) | Inhibidores de 17alfa-hidroxilasa/c17-20-liasa. | |
CY1117011T1 (el) | Παραγωγα αζολιου | |
MY163185A (en) | 2-methoxy-pyridin-4-yl derivatives | |
MX2015002705A (es) | Compuestos de piridinona para usarse en terapia fotodinamica. | |
IN2014CN04922A (hr) | ||
MY173812A (en) | 2-pyridone compound |