IN2014DN06899A - - Google Patents

Info

Publication number
IN2014DN06899A
IN2014DN06899A IN6899DEN2014A IN2014DN06899A IN 2014DN06899 A IN2014DN06899 A IN 2014DN06899A IN 6899DEN2014 A IN6899DEN2014 A IN 6899DEN2014A IN 2014DN06899 A IN2014DN06899 A IN 2014DN06899A
Authority
IN
India
Prior art keywords
analytes
sample solution
immune complexes
affinity
selectors
Prior art date
Application number
Inventor
Fred E Regnier
Nicholas B Herold
Kevin W Meyer
Original Assignee
Perfinity Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Perfinity Biosciences Inc filed Critical Perfinity Biosciences Inc
Publication of IN2014DN06899A publication Critical patent/IN2014DN06899A/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)

Abstract

A multi dimensional method is provided for simultaneously analyzing multiple analytes within a sample solution the method including: adding affinity selectors to a sample solution containing analytes to be measured the affinity selectors having an affinity for one or more of the analytes within the sample solution; allowing immune complexes to form between the affinity selectors and the analytes; partially or totally resolving the formed immune complexes from non analyte substances within the sample solution in a first dimension of separation using a selective adsorption technique; dissociating the resolved immune complexes; separating the analytes and the affinity selectors of the dissociated immune complexes from one another in a second dimension of separation using a selective adsorption technique; and resolving the analytes in accordance with their mass to charge ratios.
IN6899DEN2014 2012-02-02 2013-01-30 IN2014DN06899A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261594193P 2012-02-02 2012-02-02
PCT/US2013/023727 WO2013116260A1 (en) 2012-02-02 2013-01-30 Selector based recognition and quantification system and method for multiple analytes in a single analysis

Publications (1)

Publication Number Publication Date
IN2014DN06899A true IN2014DN06899A (en) 2015-05-15

Family

ID=48905766

Family Applications (1)

Application Number Title Priority Date Filing Date
IN6899DEN2014 IN2014DN06899A (en) 2012-02-02 2013-01-30

Country Status (12)

Country Link
EP (1) EP2820425A1 (en)
JP (1) JP2015505619A (en)
KR (1) KR20140137353A (en)
CN (1) CN104160278A (en)
AU (1) AU2013215305A1 (en)
BR (1) BR112014019134A8 (en)
CA (1) CA2863635A1 (en)
IL (1) IL233897A0 (en)
IN (1) IN2014DN06899A (en)
RU (1) RU2014135576A (en)
SG (1) SG11201404526PA (en)
WO (1) WO2013116260A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015084748A1 (en) * 2013-12-03 2015-06-11 Perfinity Biosciences, Inc A single reactor for simplified sample preparation workflows
WO2016118489A1 (en) * 2015-01-19 2016-07-28 Siscapa Assay Technologies, Inc. Combined analysis of small molecules and proteins by mass spectrometry
KR20210002673A (en) * 2018-04-30 2021-01-08 바이오테지 에이비 Protein quantitative analysis
WO2019229058A1 (en) * 2018-05-29 2019-12-05 Capsenze Biosystems Ab Method and system for providing antibody fragments suitable for online quality control
KR102198342B1 (en) * 2019-05-22 2021-01-04 연세대학교 산학협력단 Method of screening antibody and antibody screening system using the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5061790A (en) * 1989-07-10 1991-10-29 Molecular Diagnostics, Inc. Oxidative denaturation of protein analytes
US6303325B1 (en) * 1998-05-29 2001-10-16 Dade Behring Inc. Method for detecting analytes
AU2002341862C1 (en) * 2001-09-27 2009-01-29 Purdue Research Foundation Controlling isotope effects during fractionation of analytes
US20090269780A1 (en) * 2008-04-23 2009-10-29 Luminex Corporation Method for Creating a Standard for Multiple Analytes Found in a Starting Material of Biological Origin
CN103154735B (en) * 2009-05-11 2018-10-02 连接Dx股份有限公司 Method and composition for testing and analyzing object
US8455202B2 (en) * 2010-03-10 2013-06-04 Perfinity Biosciences, Inc. Affinity selector based recognition and quantification system and method for multiple analytes in a single analysis

Also Published As

Publication number Publication date
KR20140137353A (en) 2014-12-02
JP2015505619A (en) 2015-02-23
BR112014019134A2 (en) 2017-06-20
EP2820425A1 (en) 2015-01-07
CN104160278A (en) 2014-11-19
CA2863635A1 (en) 2013-08-08
SG11201404526PA (en) 2014-11-27
AU2013215305A1 (en) 2014-08-28
WO2013116260A1 (en) 2013-08-08
IL233897A0 (en) 2014-09-30
RU2014135576A (en) 2016-03-27
BR112014019134A8 (en) 2017-07-11

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