IN2014CN02611A - - Google Patents

Info

Publication number
IN2014CN02611A
IN2014CN02611A IN2611CHN2014A IN2014CN02611A IN 2014CN02611 A IN2014CN02611 A IN 2014CN02611A IN 2611CHN2014 A IN2611CHN2014 A IN 2611CHN2014A IN 2014CN02611 A IN2014CN02611 A IN 2014CN02611A
Authority
IN
India
Prior art keywords
cyclohepta
oxo
general formula
analogue
furan
Prior art date
Application number
Inventor
Tsuyoshi Tomiyama
Hiroshi Tomiyama
Masayuki Yokota
Masahiro Honma
Masafumi Yasunami
Original Assignee
Kotobuki Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kotobuki Pharmaceutical Co Ltd filed Critical Kotobuki Pharmaceutical Co Ltd
Publication of IN2014CN02611A publication Critical patent/IN2014CN02611A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

This method of cheaply and easily producing a 2 oxo 2H cyclohepta[b]furan analogue useful as a pharmaceutical intermediate with high purity and high yields. In this method a 2 oxo 2H cyclohepta[b]furan analogue represented by general formula (II) (R being a hydrogen atom or an optionally branched lower alkyl group (carbon number 1 5)) is produced by reacting in an alcohol medium in the presence of an alkali metal hydroxide malonic acid dimethyl esters with a 2 chlorotropone analogue represented by general formula (1) (R as above).
IN2611CHN2014 2011-09-12 2012-09-03 IN2014CN02611A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2011198541 2011-09-12
PCT/JP2012/072307 WO2013038931A1 (en) 2011-09-12 2012-09-03 Method of producing 2-oxo-2h-cyclohepta[b]furan analogue

Publications (1)

Publication Number Publication Date
IN2014CN02611A true IN2014CN02611A (en) 2015-08-07

Family

ID=47883162

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2611CHN2014 IN2014CN02611A (en) 2011-09-12 2012-09-03

Country Status (5)

Country Link
JP (1) JPWO2013038931A1 (en)
KR (1) KR20140063792A (en)
CN (1) CN103781773A (en)
IN (1) IN2014CN02611A (en)
WO (1) WO2013038931A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115991697A (en) * 2023-03-22 2023-04-21 中国中医科学院中药研究所 Method for preparing cycloheptatriene epsilon-caprolactone compound

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63239248A (en) * 1986-11-07 1988-10-05 Ajinomoto Co Inc Antihyperlipemic agent
JPH0816082B2 (en) * 1986-11-07 1996-02-21 味の素株式会社 Antilipemic agent
JPH0753681B2 (en) * 1989-12-25 1995-06-07 高砂香料工業株式会社 Method for producing tropone derivative
US7259187B2 (en) * 2000-12-26 2007-08-21 Research Foundation Itsuu Laboratory Tropolone derivatives

Also Published As

Publication number Publication date
CN103781773A (en) 2014-05-07
JPWO2013038931A1 (en) 2015-03-26
KR20140063792A (en) 2014-05-27
WO2013038931A1 (en) 2013-03-21

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