IN2013DE01960A - - Google Patents

Info

Publication number
IN2013DE01960A
IN2013DE01960A IN1960DE2013A IN2013DE01960A IN 2013DE01960 A IN2013DE01960 A IN 2013DE01960A IN 1960DE2013 A IN1960DE2013 A IN 1960DE2013A IN 2013DE01960 A IN2013DE01960 A IN 2013DE01960A
Authority
IN
India
Prior art keywords
chikungunya virus
seq
rnai agents
inhibition
nspl
Prior art date
Application number
Other languages
English (en)
Inventor
Parashar Deepti
A Arankalle Vidya
S Paingankar Mandar
Kumar Satyendra
D Gokhale Mangesh
B Sudeep A
S Shinde Sapna
Original Assignee
Indian Council Of Medical Res Icmr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indian Council Of Medical Res Icmr filed Critical Indian Council Of Medical Res Icmr
Priority to AU2014285701A priority Critical patent/AU2014285701C1/en
Priority to US14/899,135 priority patent/US9574195B2/en
Priority to CN201480037556.6A priority patent/CN105392886B/zh
Priority to IN1960DE2013 priority patent/IN2013DE01960A/en
Priority to EP14753163.6A priority patent/EP3017046B1/fr
Priority to PCT/IN2014/000441 priority patent/WO2015001570A1/fr
Publication of IN2013DE01960A publication Critical patent/IN2013DE01960A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering N.A.
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00Applications; Uses
    • C12N2320/30Special therapeutic applications
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IN1960DE2013 2013-07-02 2014-07-02 IN2013DE01960A (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
AU2014285701A AU2014285701C1 (en) 2013-07-02 2014-07-02 RNAi agent for inhibition of Chikungunya virus
US14/899,135 US9574195B2 (en) 2013-07-02 2014-07-02 RNAi agent for inhibition of Chikungunya virus
CN201480037556.6A CN105392886B (zh) 2013-07-02 2014-07-02 用于抑制切昆贡亚病毒的RNAi剂
IN1960DE2013 IN2013DE01960A (fr) 2013-07-02 2014-07-02
EP14753163.6A EP3017046B1 (fr) 2013-07-02 2014-07-02 Agents arni pour l'inhibition du virus du chikungunya
PCT/IN2014/000441 WO2015001570A1 (fr) 2013-07-02 2014-07-02 Agents arni pour l'inhibition du virus du chikungunya

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN1960DE2013 IN2013DE01960A (fr) 2013-07-02 2014-07-02

Publications (1)

Publication Number Publication Date
IN2013DE01960A true IN2013DE01960A (fr) 2015-06-26

Family

ID=51383914

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1960DE2013 IN2013DE01960A (fr) 2013-07-02 2014-07-02

Country Status (6)

Country Link
US (1) US9574195B2 (fr)
EP (1) EP3017046B1 (fr)
CN (1) CN105392886B (fr)
AU (1) AU2014285701C1 (fr)
IN (1) IN2013DE01960A (fr)
WO (1) WO2015001570A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10590416B2 (en) * 2017-07-06 2020-03-17 Arrowhead Pharmaceuticals, Inc. RNAi agents for inhibiting expression of alpha-ENaC and methods of use

Also Published As

Publication number Publication date
EP3017046A1 (fr) 2016-05-11
EP3017046B1 (fr) 2019-09-11
AU2014285701B2 (en) 2021-04-01
AU2014285701A1 (en) 2016-01-21
AU2014285701C1 (en) 2021-07-15
CN105392886A (zh) 2016-03-09
CN105392886B (zh) 2019-10-22
US9574195B2 (en) 2017-02-21
US20160145621A1 (en) 2016-05-26
WO2015001570A1 (fr) 2015-01-08

Similar Documents

Publication Publication Date Title
CY1124327T1 (el) Τροποποιηση της εκφρασης του ιου ηπατιτιδας β (hbv)
MX2020011806A (es) Agentes de iarn para infeccion causada por el virus de la hepatitis b.
PH12015501953A1 (en) Substituted nucleotide analogs
NZ762477A (en) Raav-based compositions and methods for treating amyotrophic lateral sclerosis
EA201790420A1 (ru) Средства, представляющие собой модифицированную двухнитевую рнк
PH12015501423A1 (en) Substituted nucleosides, nucleotides and analogs thereof
PH12016500660A1 (en) Substituted nucleosides, nucleotides and analogs thereof
EA201791417A1 (ru) Супрессия гена гентингтина, индуцированная рнк-интерференцией
MX2021006745A (es) Constructos de iarn modificados quimicamente y usos de estos.
EA201190178A1 (ru) Замещённые нуклеозидные и нуклеотидные аналоги
PH12015502018A1 (en) 3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant idh
EA202191537A1 (ru) Композиции и способы ингибирования экспрессии генов вируса гепатита в
CY1121037T1 (el) Αντινοηματικα πολυνουκλεοτιδια για να διεγειρεται παραλειψη εξονιου και μεθοδοι θεραπειας δυστροφιων
MX354676B (es) Compuestos de benzofurano para el tratamiento de infecciones por el virus de hepatitis c (hcv).
WO2020104649A3 (fr) Nouvelles compositions d'arn et méthodes d'inhibition d'angptl8
MX348555B (es) Agente preventivo o terapeutico contra la fibrosis.
TN2011000459A1 (en) Vaccine compositions and methods for treatment of mucormycosis and other fungal diseases
IL274363B2 (en) Use of a specific siRNA against protein S for the treatment of hemophilia
IN2013DE01960A (fr)
EA201790642A1 (ru) Аллель-специфическая терапия для гаплотипов болезни хантингтона
UA114603C2 (uk) Конструкція для сайленсингу гена p0 та її застосування
UA117563C2 (uk) Композиція для лікування або профілактики хвороби, асоційованої з інфекцією впл
MX2015013036A (es) Composiciones promotoras.
MX2020002110A (es) Composiciones y metodos para detectar y tratar la resistencia a la insulina.
UA111951C2 (uk) Заміщені аналоги нуклеотидів