IN2010KN00157A - - Google Patents

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Publication number
IN2010KN00157A
IN2010KN00157A IN157KON2010A IN2010KN00157A IN 2010KN00157 A IN2010KN00157 A IN 2010KN00157A IN 157KON2010 A IN157KON2010 A IN 157KON2010A IN 2010KN00157 A IN2010KN00157 A IN 2010KN00157A
Authority
IN
India
Prior art keywords
survival
proliferation
differentiation
vitro
controlling
Prior art date
Application number
Other languages
English (en)
Inventor
Lola M Reid
Randall E Mccleland
Joshua Uronis
Hsin-Lei Yao
Eliane Wauthier
Original Assignee
Univ North Carolina
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ North Carolina filed Critical Univ North Carolina
Publication of IN2010KN00157A publication Critical patent/IN2010KN00157A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0667Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/067Hepatocytes
    • C12N5/0672Stem cells; Progenitor cells; Precursor cells; Oval cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/13Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/50Proteins
    • C12N2533/52Fibronectin; Laminin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/50Proteins
    • C12N2533/54Collagen; Gelatin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/70Polysaccharides
    • C12N2533/80Hyaluronan

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
IN157KON2010 2007-06-15 2008-06-13 IN2010KN00157A (enrdf_load_stackoverflow)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94443507P 2007-06-15 2007-06-15
PCT/US2008/007397 WO2008156667A1 (en) 2007-06-15 2008-06-13 Paracrine signals from mesenchymal feeder cells and regulating expansion and differentiation of hepatic progenitors using same

Publications (1)

Publication Number Publication Date
IN2010KN00157A true IN2010KN00157A (enrdf_load_stackoverflow) 2015-08-28

Family

ID=40136896

Family Applications (1)

Application Number Title Priority Date Filing Date
IN157KON2010 IN2010KN00157A (enrdf_load_stackoverflow) 2007-06-15 2008-06-13

Country Status (13)

Country Link
US (2) US20080318316A1 (enrdf_load_stackoverflow)
EP (1) EP2171040A4 (enrdf_load_stackoverflow)
JP (1) JP2010529855A (enrdf_load_stackoverflow)
KR (1) KR20100094970A (enrdf_load_stackoverflow)
CN (1) CN101868533A (enrdf_load_stackoverflow)
AU (1) AU2008266992A1 (enrdf_load_stackoverflow)
BR (1) BRPI0813353A2 (enrdf_load_stackoverflow)
CA (1) CA2727535A1 (enrdf_load_stackoverflow)
IL (1) IL202738A0 (enrdf_load_stackoverflow)
IN (1) IN2010KN00157A (enrdf_load_stackoverflow)
MX (1) MX2009013819A (enrdf_load_stackoverflow)
TW (1) TW200916581A (enrdf_load_stackoverflow)
WO (1) WO2008156667A1 (enrdf_load_stackoverflow)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070269412A1 (en) 2003-12-02 2007-11-22 Celavie Biosciences, Llc Pluripotent cells
US20100209399A1 (en) * 2009-02-13 2010-08-19 Celavie Biosciences, Llc Brain-derived stem cells for repair of musculoskeletal system in vertebrate subjects
NZ709124A (en) * 2009-10-30 2017-06-30 Univ North Carolina Chapel Hill Multipotent stem cells from the extrahepatic biliary tree and methods of isolating same
AU2011247984B2 (en) * 2010-05-07 2015-04-30 University Of North Carolina At Chapel Hill Method of engrafting cells from solid tissues
ITMI20120896A1 (it) * 2012-05-23 2013-11-24 Bongulielmi Reto Condroitina per uso in medicina
JP6435267B2 (ja) * 2012-11-08 2018-12-05 インジェネロン インコーポレイテッド 再生細胞の培養、保存、及び投与のための培地
US9533013B2 (en) 2013-03-13 2017-01-03 University Of North Carolina At Chapel Hill Method of treating pancreatic and liver conditions by endoscopic-mediated (or laparoscopic-mediated) transplantation of stem cells into/onto bile duct walls of particular regions of the biliary tree
US11066649B2 (en) 2014-03-19 2021-07-20 Institut National De La Sante Et De La Recherche Medicale (Inserm) Method for inducing human cholangiocyte differentiation
US10428311B2 (en) * 2014-07-16 2019-10-01 Osaka University Method for enhancing activity of laminin fragments as cell culture matrix
CN108431209B (zh) * 2015-06-12 2023-02-10 新加坡科技研究局 肝脏干细胞的衍生和成熟肝细胞类型及其用途
US20170369849A1 (en) * 2016-05-11 2017-12-28 The University Of North Carolina At Chapel Hill Compositions and methods for bioengineered tissues
US20200010806A1 (en) * 2017-02-01 2020-01-09 Phoenixsongs Biologicals, Inc. Compositions and methods comprising co-culture of hepatocytes
WO2019060790A1 (en) 2017-09-22 2019-03-28 Lifenet Health PLATE-BASED HEPATOCYTES AND PREPARATION AND USES THEREOF
WO2020075534A1 (ja) * 2018-10-11 2020-04-16 一丸ファルコス株式会社 神経幹細胞増殖用培地

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1559778A1 (en) * 1991-08-07 2005-08-03 Albert Einstein College Of Medicine Of Yeshiva University Proliferation of hepatocyte precursors
US6069005A (en) 1991-08-07 2000-05-30 Albert Einstein College Of Medicine Of Yeshwa University Hapatoblasts and method of isolating same
EP1147179B1 (en) 1999-01-19 2008-11-12 The University of North Carolina at Chapel Hill Human liver progenitors
US7456017B2 (en) * 1999-10-01 2008-11-25 University Of North Carolina At Chapel Hill Processes for clonal growth of hepatic progenitor cells
SI1490480T1 (sl) * 2002-03-15 2016-06-30 University of North Carolina at Chapel Hill, Office of Commercialization and Economic Development Primitivne in proksimalne jetrne matične celice
KR20080097985A (ko) * 2005-11-16 2008-11-06 유니버시티 오브 노스캐롤라이나 앳 채플 힐 간 전구체의 확대 또는 분화를 위한 세포외 매트릭스 성분
WO2008002523A2 (en) * 2006-06-28 2008-01-03 Vesta Therapeutics, Inc. Matrix and method for isolation of hepatic progenitor cells
WO2008109659A2 (en) * 2007-03-06 2008-09-12 University Of North Carolina At Chapel Hill Complexes of hyaluronans, other matrix components, hormones and growth factors for maintenance, expansion and/or differentiation of cells

Also Published As

Publication number Publication date
WO2008156667A1 (en) 2008-12-24
AU2008266992A1 (en) 2008-12-24
CA2727535A1 (en) 2008-12-24
EP2171040A4 (en) 2010-08-04
IL202738A0 (en) 2011-08-01
KR20100094970A (ko) 2010-08-27
US8404483B2 (en) 2013-03-26
CN101868533A (zh) 2010-10-20
BRPI0813353A2 (pt) 2014-10-14
EP2171040A1 (en) 2010-04-07
US20080318316A1 (en) 2008-12-25
MX2009013819A (es) 2010-05-17
US20110065188A1 (en) 2011-03-17
TW200916581A (en) 2009-04-16
JP2010529855A (ja) 2010-09-02

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