IN161343B - - Google Patents

Info

Publication number
IN161343B
IN161343B IN1163/CAL/83A IN1163CA1983A IN161343B IN 161343 B IN161343 B IN 161343B IN 1163CA1983 A IN1163CA1983 A IN 1163CA1983A IN 161343 B IN161343 B IN 161343B
Authority
IN
India
Prior art keywords
atom
radical
formula
saturated
substituted
Prior art date
Application number
IN1163/CAL/83A
Inventor
Roy Arne Olofson
Gary Paul Wooden
Jonathan Thomas Martz
Original Assignee
Poudres & Explosifs Ste Nale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poudres & Explosifs Ste Nale filed Critical Poudres & Explosifs Ste Nale
Publication of IN161343B publication Critical patent/IN161343B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D249/18—Benzotriazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D323/00—Heterocyclic compounds containing more than two oxygen atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1. Process for preparing vinyl carbamates of the formula I : see diagramm : EP0104984,P29,F1 in which R1 and R2 , which may be identical or different, denote a hydrogen atom, or a substituted or unsubstituted, saturated or unsaturated aliphatic radical, or alternatively R1 and R2 , together with the carbon atom to which they are attached, form a ring which is saturated or unsaturated and substituted or unsubstituted, R3 and R4 are identical or different and denote a hydrogen atom, an aliphatic or cycloaliphatic radical, substituted or unsubstituted and saturated or unsaturated, the unsaturation occurring on a carbon atom which is not adjacent to the nitrogen atom, a radical or formula see diagramm : EP0104984,P29,F2 in which Y is an alkyl radical, R1 and R2 are defined as above and Z is a hydrocarbon chain containing 2 to 20 carbon atoms, or Z is a hydrocarbon chain consisting of 2 to 20 carbon atoms and containing, in addition, hetero atoms W, W being O, S, NR", each hetero atom being separated from another hetero atom by at least two carbon atoms and R" being a hydrocarbon radical, or Z is a group see diagramm : EP0104984,P29,F3 10, or a substituted or unsubstituted aromatic radical, or alternatively R3 and R4 form, together with the nitrogen atom to which they are attached, a substituted or unsubstituted, saturated or unsaturated heterocycle, R3 and R4 form, together with the nitrogen atom to which they are attached, a heterocycle which is part of a substituted or unsubstituted, saturated or unsaturated fused ring system, R3 and R4 form, together with the nitrogen atom to which they are attached, a heterocycle which contains at least one other hetero atom which is O, S, N or NRx , Rx being a hydrocarbon radical, and/or a nitrogen atom which forms a vinyl carbamate group, R3 and R4 form, together with the nitrogen atom to which they are attached, a ring of formula see diagramm : EP0104984,P29,F4 in which Z, R1 and R2 have the above meaning, R3 and R4 form a piperazine ring together with the nitrogen atom to which they are attached, the two nitrogen atoms of the piperazine ring bearing the group of formula : see diagramm : EP0104984,P29,F5 in which R1 and R2 have the above meaning, which consists in heating an alpha-halogenated carbamate of formula (II) : see diagramm : EP0104984,P30,F1 in which R1 , R2 , R3 and R4 are defined as above and when, in the compound of formula (I), R3 and R4 denote a radical which contains a vinyl carbamate group, the latter is present in the compound of the formula (II) in the form of a saturated carbamate containing a hydrogen atom at the beta-position and X at the alpha-position, X is a halogen atom, at a temperature of between 80 degrees C and 200 degrees C for a period of between a few minutes and several hours.
IN1163/CAL/83A 1982-09-24 1983-09-23 IN161343B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42346582A 1982-09-24 1982-09-24

Publications (1)

Publication Number Publication Date
IN161343B true IN161343B (en) 1987-11-14

Family

ID=23679002

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1163/CAL/83A IN161343B (en) 1982-09-24 1983-09-23

Country Status (10)

Country Link
EP (1) EP0104984B1 (en)
JP (2) JPS5980653A (en)
AT (1) ATE52768T1 (en)
CA (1) CA1235121A (en)
DE (1) DE3381560D1 (en)
DK (1) DK433383A (en)
ES (1) ES8503645A1 (en)
FR (1) FR2533561B1 (en)
IL (1) IL69710A (en)
IN (1) IN161343B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2564838B1 (en) * 1984-05-25 1986-11-07 Sanofi Sa PROCESS FOR DEALKYLATION OF ALKALOIDS AND INTERMEDIATES
US5070215A (en) * 1989-05-02 1991-12-03 Bausch & Lomb Incorporated Novel vinyl carbonate and vinyl carbamate contact lens material monomers
GB2321900A (en) * 1997-02-11 1998-08-12 Procter & Gamble Cationic surfactants

Also Published As

Publication number Publication date
IL69710A (en) 1989-03-31
ES525858A0 (en) 1985-03-16
ES8503645A1 (en) 1985-03-16
EP0104984A3 (en) 1985-11-21
CA1235121A (en) 1988-04-12
JP2505962B2 (en) 1996-06-12
EP0104984B1 (en) 1990-05-16
ATE52768T1 (en) 1990-06-15
EP0104984A2 (en) 1984-04-04
DE3381560D1 (en) 1990-06-21
JPH0526776B2 (en) 1993-04-19
DK433383A (en) 1984-03-25
IL69710A0 (en) 1983-12-30
FR2533561A1 (en) 1984-03-30
DK433383D0 (en) 1983-09-22
JPS5980653A (en) 1984-05-10
FR2533561B1 (en) 1986-07-25
JPH06312970A (en) 1994-11-08

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