GB2006759A - omega -Mercapto-propionamides and Pharmaceutical Preparations containing them - Google Patents

omega -Mercapto-propionamides and Pharmaceutical Preparations containing them

Info

Publication number
GB2006759A
GB2006759A GB7838509A GB7838509A GB2006759A GB 2006759 A GB2006759 A GB 2006759A GB 7838509 A GB7838509 A GB 7838509A GB 7838509 A GB7838509 A GB 7838509A GB 2006759 A GB2006759 A GB 2006759A
Authority
GB
United Kingdom
Prior art keywords
lower alkyl
hydrogen atom
pharmaceutical preparations
propionamides
mercapto
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB7838509A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Science Union et Cie
Original Assignee
Science Union et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union et Cie filed Critical Science Union et Cie
Publication of GB2006759A publication Critical patent/GB2006759A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/12—1,4-Thiazines; Hydrogenated 1,4-thiazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

Novel omega -mercapto propionamides of the general formula (I> <IMAGE> (in which R is a hydrogen atom, a lower alkyl, lower alkenyl, aryl lower alkyl or an aryl radical, R2 is a hydrogen atom or a lower alkyl or lower cycloalkyl radical, Z is a sulphur atom or a sulphoxide or a sulphonyl group, R3 is a hydrogen atom or a lower alkyl radical, m is 1 or 2, n is 1 or 2, p is 0, 1 or 2, and X is a hydroxy, lower alkoxy or an amino group) have an important anti-hypertensive action and accordingly may be made up with suitable carriers into pharmaceutical preparations which advantageously may also contain diuretic agent and/or vasodilators.
GB7838509A 1977-09-28 1978-09-28 omega -Mercapto-propionamides and Pharmaceutical Preparations containing them Withdrawn GB2006759A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7729109A FR2404635A1 (en) 1977-09-28 1977-09-28 NEW THIOPROPRIONYLAMIDES, THEIR OBTAINING PROCEDURES AND THEIR USE IN THERAPEUTICS

Publications (1)

Publication Number Publication Date
GB2006759A true GB2006759A (en) 1979-05-10

Family

ID=9195844

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7838509A Withdrawn GB2006759A (en) 1977-09-28 1978-09-28 omega -Mercapto-propionamides and Pharmaceutical Preparations containing them

Country Status (5)

Country Link
BE (1) BE870801A (en)
FR (1) FR2404635A1 (en)
GB (1) GB2006759A (en)
SU (1) SU803859A3 (en)
ZA (1) ZA785509B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4450275A (en) * 1978-10-05 1984-05-22 Yoshitomi Pharmaceutical Industries, Ltd. Cyclic iminocarboxylic acid derivatives

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU528115B2 (en) * 1978-04-08 1983-04-14 Santen Pharmaceutical Co. Ltd. Antihypertensive 4-thiazolidine/carboxylic acids
ZA783013B (en) * 1978-05-22 1979-06-27 Squibb & Sons Inc Derivatives of thiazolidinecarboxylic acids and related acids
JPS5531022A (en) * 1978-08-24 1980-03-05 Yoshitomi Pharmaceut Ind Ltd Hydroxamic acid derivative and its preparation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4450275A (en) * 1978-10-05 1984-05-22 Yoshitomi Pharmaceutical Industries, Ltd. Cyclic iminocarboxylic acid derivatives

Also Published As

Publication number Publication date
FR2404635A1 (en) 1979-04-27
FR2404635B1 (en) 1980-08-01
ZA785509B (en) 1979-08-29
BE870801A (en) 1979-03-27
SU803859A3 (en) 1981-02-07

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)