IL96082A0 - Aminopyridinylaminophenols and related compounds,a process and intermediates for their preparation and their use as medicaments - Google Patents
Aminopyridinylaminophenols and related compounds,a process and intermediates for their preparation and their use as medicamentsInfo
- Publication number
- IL96082A0 IL96082A0 IL96082A IL9608290A IL96082A0 IL 96082 A0 IL96082 A0 IL 96082A0 IL 96082 A IL96082 A IL 96082A IL 9608290 A IL9608290 A IL 9608290A IL 96082 A0 IL96082 A0 IL 96082A0
- Authority
- IL
- Israel
- Prior art keywords
- aminopyridinylaminophenols
- medicaments
- intermediates
- preparation
- related compounds
- Prior art date
Links
- SANGGOBGSYNQOF-UHFFFAOYSA-N 3-amino-2-(pyridin-2-ylamino)phenol Chemical class NC1=CC=CC(O)=C1NC1=CC=CC=N1 SANGGOBGSYNQOF-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/425,713 US4959378A (en) | 1989-10-24 | 1989-10-24 | Aminopyridinylaminophenol compounds useful as topical antiinflammatory agents for the treatment of skin disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL96082A0 true IL96082A0 (en) | 1991-07-18 |
Family
ID=23687726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL96082A IL96082A0 (en) | 1989-10-24 | 1990-10-22 | Aminopyridinylaminophenols and related compounds,a process and intermediates for their preparation and their use as medicaments |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4959378A (cg-RX-API-DMAC7.html) |
| EP (1) | EP0424848A3 (cg-RX-API-DMAC7.html) |
| JP (1) | JPH03151364A (cg-RX-API-DMAC7.html) |
| KR (1) | KR910007881A (cg-RX-API-DMAC7.html) |
| AU (1) | AU6485790A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2028285A1 (cg-RX-API-DMAC7.html) |
| FI (1) | FI905192A7 (cg-RX-API-DMAC7.html) |
| IE (1) | IE903809A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL96082A0 (cg-RX-API-DMAC7.html) |
| NO (1) | NO904576L (cg-RX-API-DMAC7.html) |
| PT (1) | PT95652A (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA908459B (cg-RX-API-DMAC7.html) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990009985A1 (en) * | 1989-02-23 | 1990-09-07 | Otsuka Pharmaceutical Factory, Inc. | p-AMINOPHENOL DERIVATIVE AND PRODUCTION AND APPLICATION THEREOF |
| US4959378A (en) * | 1989-10-24 | 1990-09-25 | Hoechst-Roussel Pharmaceuticals Inc. | Aminopyridinylaminophenol compounds useful as topical antiinflammatory agents for the treatment of skin disorders |
| US6022884A (en) | 1997-11-07 | 2000-02-08 | Amgen Inc. | Substituted pyridine compounds and methods of use |
| US6455554B1 (en) | 1999-06-07 | 2002-09-24 | Targacept, Inc. | Oxopyridinyl pharmaceutical compositions and methods for use |
| EP1554572B1 (en) | 2001-07-25 | 2009-10-14 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| WO2006045514A1 (en) * | 2004-10-20 | 2006-05-04 | Applied Research Systems Ars Holding N.V. | 3-arylamino pyridine derivatives |
| CN102379684B (zh) | 2005-04-28 | 2014-11-19 | 普罗透斯数字保健公司 | 药物信息系统 |
| CN101594878A (zh) | 2006-09-18 | 2009-12-02 | 雷普特药品公司 | 通过给予受体相关蛋白（rap）-缀合物对肝病症的治疗 |
| NZ616673A (en) | 2009-02-20 | 2014-08-29 | To Bbb Holding B V | Glutathione-based drug delivery system |
| CN110075069A (zh) | 2009-05-06 | 2019-08-02 | 实验室护肤股份有限公司 | 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其应用 |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB750925A (en) * | 1953-10-26 | 1956-06-20 | Wellcome Found | Improvements in and relating to pyridine derivatives and the manufacture thereof |
| US3118884A (en) * | 1959-10-19 | 1964-01-21 | Schering Corp | Derivatives of 3-azaphenothiazine and 3-azaphenoxazine |
| DE1795544A1 (de) * | 1964-08-29 | 1973-02-15 | Degussa | Verfahren zur herstellung von phenylamino-pyridinen |
| DE1795499A1 (de) * | 1964-08-29 | 1972-02-10 | Degussa | Neue substituierte Diaminopyridine |
| DE1568426A1 (de) * | 1966-11-16 | 1970-04-02 | Degussa | Verfahren zur Herstellung von neuen N-aromatisch substituierten Saeureamiden |
| FR8363M (cg-RX-API-DMAC7.html) * | 1967-02-01 | 1971-02-15 | ||
| US3495969A (en) * | 1967-09-25 | 1970-02-17 | Mobil Oil Corp | Substituted nitropyridines as herbicides |
| US3576616A (en) * | 1969-05-15 | 1971-04-27 | Monsanto Co | Herbicidal compositions and methods |
| US3721676A (en) * | 1969-11-12 | 1973-03-20 | Merck & Co Inc | Certain 3-amino-2(1h)pyridones |
| GB2073736B (en) * | 1979-10-03 | 1984-02-01 | Ici Ltd | Process for preparing pyridinyloxyphenoxy compounds and derivatives thereof |
| IE56702B1 (en) * | 1982-12-01 | 1991-11-06 | Usv Pharma Corp | Antiinflammatory antiallergic compounds |
| US4959378A (en) * | 1989-10-24 | 1990-09-25 | Hoechst-Roussel Pharmaceuticals Inc. | Aminopyridinylaminophenol compounds useful as topical antiinflammatory agents for the treatment of skin disorders |
-
1989
- 1989-10-24 US US07/425,713 patent/US4959378A/en not_active Expired - Lifetime
-
1990
- 1990-10-22 EP EP19900120237 patent/EP0424848A3/en not_active Withdrawn
- 1990-10-22 KR KR1019900016854A patent/KR910007881A/ko not_active Withdrawn
- 1990-10-22 IL IL96082A patent/IL96082A0/xx unknown
- 1990-10-22 FI FI905192A patent/FI905192A7/fi not_active Application Discontinuation
- 1990-10-23 ZA ZA908459A patent/ZA908459B/xx unknown
- 1990-10-23 PT PT95652A patent/PT95652A/pt not_active Application Discontinuation
- 1990-10-23 NO NO90904576A patent/NO904576L/no unknown
- 1990-10-23 AU AU64857/90A patent/AU6485790A/en not_active Abandoned
- 1990-10-23 IE IE380990A patent/IE903809A1/en unknown
- 1990-10-23 JP JP2283579A patent/JPH03151364A/ja active Pending
- 1990-10-23 CA CA002028285A patent/CA2028285A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU6485790A (en) | 1991-05-02 |
| FI905192A0 (fi) | 1990-10-22 |
| EP0424848A3 (en) | 1991-10-02 |
| ZA908459B (en) | 1991-08-28 |
| CA2028285A1 (en) | 1991-04-25 |
| PT95652A (pt) | 1991-09-13 |
| IE903809A1 (en) | 1991-04-24 |
| KR910007881A (ko) | 1991-05-30 |
| JPH03151364A (ja) | 1991-06-27 |
| NO904576L (no) | 1991-04-25 |
| NO904576D0 (no) | 1990-10-23 |
| US4959378A (en) | 1990-09-25 |
| US4959378B1 (cg-RX-API-DMAC7.html) | 1993-08-10 |
| FI905192A7 (fi) | 1991-04-25 |
| EP0424848A2 (en) | 1991-05-02 |
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