IL95839A - Quinoline derivatives, the process for their preparation and medicinal preparations containing them - Google Patents
Quinoline derivatives, the process for their preparation and medicinal preparations containing themInfo
- Publication number
- IL95839A IL95839A IL9583990A IL9583990A IL95839A IL 95839 A IL95839 A IL 95839A IL 9583990 A IL9583990 A IL 9583990A IL 9583990 A IL9583990 A IL 9583990A IL 95839 A IL95839 A IL 95839A
- Authority
- IL
- Israel
- Prior art keywords
- dihydro
- oxo
- methyl
- compound
- chlorophenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Measurement Of Radiation (AREA)
- Holo Graphy (AREA)
- Detergent Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP26278289 | 1989-10-06 | ||
JP32229089 | 1989-12-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL95839A0 IL95839A0 (en) | 1991-06-30 |
IL95839A true IL95839A (en) | 1995-03-15 |
Family
ID=26545706
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL9583990A IL95839A (en) | 1989-10-06 | 1990-09-28 | Quinoline derivatives, the process for their preparation and medicinal preparations containing them |
Country Status (17)
Country | Link |
---|---|
US (1) | US5223513A (ko) |
EP (1) | EP0421456B1 (ko) |
KR (1) | KR910007883A (ko) |
CN (1) | CN1050715A (ko) |
AT (1) | ATE116301T1 (ko) |
AU (1) | AU629048B2 (ko) |
CA (1) | CA2026890C (ko) |
DE (1) | DE69015541T2 (ko) |
FI (1) | FI904915A0 (ko) |
HU (1) | HUT55364A (ko) |
IE (1) | IE903454A1 (ko) |
IL (1) | IL95839A (ko) |
NO (1) | NO904300L (ko) |
NZ (1) | NZ235582A (ko) |
PT (1) | PT95515A (ko) |
RU (1) | RU2001910C1 (ko) |
TW (1) | TW205037B (ko) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH03181465A (ja) * | 1989-12-11 | 1991-08-07 | Takeda Chem Ind Ltd | キノリン誘導体 |
CA2108014A1 (en) * | 1991-04-26 | 1992-10-27 | Ernest S. Hamanaka | 4-aryl-3-(heteroarylureido)quinoline derivatives |
WO1993015058A1 (en) * | 1992-01-23 | 1993-08-05 | Pfizer Inc. | 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxo-quinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents |
TW241258B (ko) * | 1992-04-15 | 1995-02-21 | Takeda Pharm Industry Co Ltd | |
BR9306421A (pt) * | 1992-05-28 | 1998-09-15 | Pfizer | Novos derivados n-aril e n-heteroariluréia como inbidores da acilcoenzima a:colesterol aciltransferase (acat) |
EP0585913B1 (en) * | 1992-09-04 | 1997-12-29 | Takeda Chemical Industries, Ltd. | Condensed heterocyclic compounds, their production and use |
US5565472A (en) * | 1992-12-21 | 1996-10-15 | Pfizer Inc. | 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxo-quinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents |
NZ264063A (en) * | 1993-08-13 | 1995-11-27 | Nihon Nohyaku Co Ltd | N-(2-phenylpyrid-3-yl)- and n-(4-phenylpyrimidin-5-yl)-n'-phenylurea derivatives and pharmaceutical compositions |
TW263498B (ko) * | 1993-11-10 | 1995-11-21 | Takeda Pharm Industry Co Ltd | |
US6133326A (en) | 1994-08-31 | 2000-10-17 | Pfizer Inc | Compositions and methods for decreasing sebum production |
US5843957A (en) * | 1995-05-19 | 1998-12-01 | Sumitomo Pharmaceuticals Company, Ltd. | Naphthyridine derivatives |
US5972961A (en) * | 1997-08-28 | 1999-10-26 | Bristol-Myers Squibb Company | 4-aryl-3-aminoquinoline-2-one derivatives as potassium channel modulators |
EP1086948A4 (en) | 1998-02-25 | 2004-03-10 | Sumitomo Pharma | PYRIDONE DERIVATIVES AND THEIR MANUFACTURING PROCESS |
US6452008B2 (en) | 1998-02-25 | 2002-09-17 | Sumitomo Pharmaceuticals Company, Limited | Pyridone derivatives and process for preparing the same |
YU57502A (sh) | 2000-02-02 | 2006-01-16 | Warner-Lambert Company | Dvojni inhibitori sinteze estara holesterola i estara voska kod poremećaja lojne žlezde |
JP4300457B2 (ja) * | 2001-03-02 | 2009-07-22 | 住友化学株式会社 | キノリン−3−カルボン酸化合物の製造方法 |
US7825131B2 (en) | 2003-09-23 | 2010-11-02 | Merck Sharp & Dohme Corp. | Quinoline potassium channel inhibitors |
CA2849945A1 (en) | 2011-11-04 | 2013-05-10 | F.Hoffmann-La Roche Ag | New aryl-quinoline derivatives |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1216878B (de) * | 1963-04-02 | 1966-05-18 | Cassella Farbwerke Mainkur Ag | Verfahren zur Herstellung von coronargefaesserweiternden Derivaten des 7-Hydroxy-2-oxo-1, 2-dihydrochinolins |
NO133758C (ko) * | 1970-04-04 | 1976-06-23 | Takeda Chemical Industries Ltd | |
JPS555502B1 (ko) * | 1971-07-31 | 1980-02-07 | ||
US4530931A (en) * | 1983-01-03 | 1985-07-23 | Usv Pharmaceutical Corp. | 8-Quinoline carbanilates for the inhibition of lipolysis |
EP0166354B1 (en) * | 1984-06-26 | 1992-08-05 | Merck & Co. Inc. | Benzofused lactam compounds and pharmaceutical compositions containing them |
IE892088L (en) * | 1988-07-12 | 1990-01-12 | William Henry Deryk Morris | Quinoline derivatives, their production and use |
-
1990
- 1990-09-20 TW TW079107912A patent/TW205037B/zh active
- 1990-09-25 IE IE345490A patent/IE903454A1/en unknown
- 1990-09-25 US US07/587,795 patent/US5223513A/en not_active Expired - Fee Related
- 1990-09-28 AU AU63707/90A patent/AU629048B2/en not_active Ceased
- 1990-09-28 IL IL9583990A patent/IL95839A/en not_active IP Right Cessation
- 1990-10-03 NO NO90904300A patent/NO904300L/no unknown
- 1990-10-04 CA CA002026890A patent/CA2026890C/en not_active Expired - Fee Related
- 1990-10-04 PT PT95515A patent/PT95515A/pt not_active Application Discontinuation
- 1990-10-05 NZ NZ235582A patent/NZ235582A/en unknown
- 1990-10-05 CN CN90108222A patent/CN1050715A/zh active Pending
- 1990-10-05 DE DE69015541T patent/DE69015541T2/de not_active Expired - Fee Related
- 1990-10-05 RU SU904831426A patent/RU2001910C1/ru active
- 1990-10-05 EP EP90119128A patent/EP0421456B1/en not_active Expired - Lifetime
- 1990-10-05 HU HU906360A patent/HUT55364A/hu unknown
- 1990-10-05 AT AT90119128T patent/ATE116301T1/de not_active IP Right Cessation
- 1990-10-05 FI FI904915A patent/FI904915A0/fi not_active Application Discontinuation
- 1990-10-06 KR KR1019900015908A patent/KR910007883A/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HU906360D0 (en) | 1991-04-29 |
DE69015541T2 (de) | 1995-06-01 |
CA2026890C (en) | 2001-09-18 |
EP0421456A3 (en) | 1991-05-29 |
CN1050715A (zh) | 1991-04-17 |
CA2026890A1 (en) | 1991-04-07 |
FI904915A0 (fi) | 1990-10-05 |
IE903454A1 (en) | 1991-04-10 |
NO904300L (no) | 1991-04-08 |
RU2001910C1 (ru) | 1993-10-30 |
NO904300D0 (no) | 1990-10-03 |
KR910007883A (ko) | 1991-05-30 |
HUT55364A (en) | 1991-05-28 |
JPH03223254A (ja) | 1991-10-02 |
TW205037B (ko) | 1993-05-01 |
NZ235582A (en) | 1992-03-26 |
IL95839A0 (en) | 1991-06-30 |
PT95515A (pt) | 1991-08-14 |
AU6370790A (en) | 1991-04-11 |
AU629048B2 (en) | 1992-09-24 |
US5223513A (en) | 1993-06-29 |
EP0421456A2 (en) | 1991-04-10 |
ATE116301T1 (de) | 1995-01-15 |
EP0421456B1 (en) | 1994-12-28 |
DE69015541D1 (de) | 1995-02-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2026890C (en) | Quinoline derivatives, their production and use | |
EP0354994B1 (en) | Quinoline derivatives, their production and use | |
US3702849A (en) | 4-(isoquinolin-1-yl) piperazine-1-carboxylic acid esters | |
US5700810A (en) | Condensed heterocyclic compounds, their production and use | |
NO171785B (no) | Analogifremgangsmaate for fremstilling av terapeutisk virksomme kinazolinderivater | |
EP0182165A1 (en) | Thienyl condensed-pyrazole derivatives | |
US4276295A (en) | 3-Aromatic moiety substituted-4(3H)-quinazolinones, process for production thereof, and use thereof | |
CA2071224C (en) | Quinoline derivatives, their production and use | |
EP0481383A1 (en) | Heterocyclic amine derivatives, their production and use | |
US5278186A (en) | Chromene derivatives, their production and use | |
US5264454A (en) | Certain 2-oxo-tetrahydro-cycloalkyl-benzopyran-3yl ureas having acyl-CoA-cholesterol acyl transferase inhibitory activity | |
JPH0710844A (ja) | 縮合複素環化合物、その製造法および剤 | |
HINO et al. | Synthesis and pharmacological activities of 3-phenyl-2-(1-piperazinyl) quinolines and related compounds | |
IE51542B1 (en) | Therapeutic agents | |
RU1838301C (ru) | Способ получени производного хинолина или его соли | |
GB2085441A (en) | Therapeutic agents | |
JP3004041B2 (ja) | キノリン誘導体、その製法および用途 | |
JPH0753714B2 (ja) | Acat阻害剤、キノリン誘導体及びその製造法 | |
EP0126342A2 (en) | 3-Alkyl-8-chloro-5,6-dihydrofuro-[3,2-f]-1,2-benzisoxazole-6-carboxylic acids | |
KR820000099B1 (ko) | 피리도[2, 1-b] 퀴나졸린 유도체의 제조방법 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RH | Patent void |