IL94228A - A method for isolating and purifying transpirin receptor proteins from bacteria and vaccines containing them - Google Patents
A method for isolating and purifying transpirin receptor proteins from bacteria and vaccines containing themInfo
- Publication number
- IL94228A IL94228A IL9422890A IL9422890A IL94228A IL 94228 A IL94228 A IL 94228A IL 9422890 A IL9422890 A IL 9422890A IL 9422890 A IL9422890 A IL 9422890A IL 94228 A IL94228 A IL 94228A
- Authority
- IL
- Israel
- Prior art keywords
- transferrin
- transferrin receptor
- vaccine
- haemophilus
- receptor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL14497301A IL144973A0 (en) | 1989-04-27 | 2001-08-19 | A vaccine which provides protective immunity against a bacterial pathogen |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34435689A | 1989-04-27 | 1989-04-27 | |
US07/507,481 US5292869A (en) | 1989-04-27 | 1990-04-09 | Method for isolating and purifying transferrin and lactoferrin receptor proteins from bacteria and the preparation of vaccines containing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
IL94228A0 IL94228A0 (en) | 1991-01-31 |
IL94228A true IL94228A (en) | 2001-03-19 |
Family
ID=26993881
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL9422890A IL94228A (en) | 1989-04-27 | 1990-04-27 | A method for isolating and purifying transpirin receptor proteins from bacteria and vaccines containing them |
IL14497301A IL144973A0 (en) | 1989-04-27 | 2001-08-19 | A vaccine which provides protective immunity against a bacterial pathogen |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14497301A IL144973A0 (en) | 1989-04-27 | 2001-08-19 | A vaccine which provides protective immunity against a bacterial pathogen |
Country Status (12)
Country | Link |
---|---|
US (1) | US5292869A (fr) |
EP (1) | EP0528787B1 (fr) |
KR (1) | KR100240974B1 (fr) |
AT (1) | ATE173935T1 (fr) |
AU (1) | AU649950B2 (fr) |
CA (1) | CA2051808C (fr) |
DE (1) | DE69032806T2 (fr) |
DK (1) | DK0528787T3 (fr) |
ES (1) | ES2127184T3 (fr) |
IL (2) | IL94228A (fr) |
NZ (2) | NZ247967A (fr) |
WO (1) | WO1990012591A1 (fr) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1378245T3 (da) * | 1990-08-23 | 2009-10-26 | Univ North Carolina | Transferrin-bindende-proteiner fra neisseria gonorrhoeae og neisseria meningitidis. Deres anvendelse i en vaccine |
FR2682041B1 (fr) * | 1991-10-03 | 1994-01-14 | Pasteur Merieux Serums Vaccins | Vaccin contre les infections a neisseria meningitidis. |
FR2682114B1 (fr) * | 1991-10-03 | 1996-02-23 | Pasteur Merieux Serums Vacc | Vaccin de sous-unite contre les infections a neisseria meningitidis et sous-unites correspondantes a l'etat purifie. |
US5417971A (en) * | 1991-10-22 | 1995-05-23 | University Of Saskatchewan | Vaccines for Actinobacillus pleuropneumoniae |
FR2692592B1 (fr) * | 1992-06-19 | 1995-03-31 | Pasteur Merieux Serums Vacc | Fragments d'ADN codant pour les sous-unités du récepteur de la transferrine de Neisseria meningitidis et procédés les exprimant. |
US5534256A (en) * | 1992-07-02 | 1996-07-09 | University Of Saskatchewan | Haemophilus somnus outer membrane protein extract enriched with iron-regulated proteins |
WO1994005783A1 (fr) * | 1992-09-07 | 1994-03-17 | Bioproperties (Australia) Pty. Limited | Nouvel organisme du genre haemophilis et vaccins le contenant |
CA2182976C (fr) * | 1994-02-09 | 2011-07-12 | Daryll A. Emery | Immunisation active au moyen d'un recepteur proteique de siderophore |
US5830479A (en) * | 1994-02-09 | 1998-11-03 | Willmar Poultry Company, Inc. | Active immunization using a siderophore receptor protein |
US6121427A (en) * | 1994-10-24 | 2000-09-19 | Connaught Laboratories Limited | Major outer membrane protein CD of branhamella |
US6440425B1 (en) * | 1995-05-01 | 2002-08-27 | Aventis Pasteur Limited | High molecular weight major outer membrane protein of moraxella |
US5817789A (en) | 1995-06-06 | 1998-10-06 | Transkaryotic Therapies, Inc. | Chimeric proteins for use in transport of a selected substance into cells |
US6290970B1 (en) | 1995-10-11 | 2001-09-18 | Aventis Pasteur Limited | Transferrin receptor protein of Moraxella |
US6048539A (en) * | 1995-11-02 | 2000-04-11 | Connaught Laboratories Limited | Lactoferrin receptor protein |
EP0863986A1 (fr) * | 1995-12-01 | 1998-09-16 | Reggie Y. C. Lo | Proteines de pasteurella haemolytica liant la transferine, et vaccins contenant ces proteines |
US6610506B1 (en) | 1995-12-01 | 2003-08-26 | University Technologies International, Inc. | Transferrin binding proteins of Pasteurella haemolytica and vaccines containing same |
US6440701B1 (en) | 1996-03-08 | 2002-08-27 | Aventis Pasteur Limited | Transferrin receptor genes of Moraxella |
US6090576A (en) * | 1996-03-08 | 2000-07-18 | Connaught Laboratories Limited | DNA encoding a transferrin receptor of Moraxella |
DK1005487T3 (da) * | 1997-01-31 | 2006-11-13 | Wyeth Corp | Ydre 74 kD-membranprotein fra Moraxella catarrhalis |
JP2001502925A (ja) * | 1997-06-03 | 2001-03-06 | コノート ラボラトリーズ リミテッド | モラクセラのラクトフェリン受容体遺伝子 |
US5977337A (en) * | 1997-06-03 | 1999-11-02 | Connaught Laboratories Limited | Lactoferrin receptor genes of Moraxella |
FR2767060B1 (fr) * | 1997-08-07 | 2000-02-11 | Pasteur Merieux Serums Vacc | Vaccin meningocoque comportant la valence de souche bz83 |
GB9810084D0 (en) | 1998-05-11 | 1998-07-08 | Cortecs Uk Ltd | Proteins |
FR2785293B1 (fr) | 1998-10-30 | 2002-07-05 | Pasteur Merieux Serums Vacc | Acides nucleiques et polypeptides specifiques des souches pathogenes du genre neisseria |
US10967045B2 (en) | 1998-11-02 | 2021-04-06 | Secretary of State for Health and Social Care | Multicomponent meningococcal vaccine |
GB9823978D0 (en) * | 1998-11-02 | 1998-12-30 | Microbiological Res Authority | Multicomponent meningococcal vaccine |
US6391316B1 (en) * | 1999-03-10 | 2002-05-21 | University Of Saskatchewan | Vaccine compositions comprising Haemophilus somnus transferrin-binding proteins and methods of use |
US7241449B1 (en) | 1999-04-12 | 2007-07-10 | Aventis Pasteur Limited | Transferrin receptor genes of moraxella |
US6682754B2 (en) | 1999-11-24 | 2004-01-27 | Willmar Poultry Company, Inc. | Ovo delivery of an immunogen containing implant |
BR0206293B1 (pt) * | 2001-01-03 | 2015-01-20 | Epitopix Llc | composições compreendendo polipeptídeos receptores de sideróforos e porinas de micróbio gram-negativo, bem como métodos de isolar polipeptídeos de membrana externa |
US8129504B2 (en) * | 2001-08-30 | 2012-03-06 | Biorexis Technology, Inc. | Oral delivery of modified transferrin fusion proteins |
US7759055B2 (en) * | 2002-08-28 | 2010-07-20 | Millipore Corporation | Compositions of solution for sequencing reaction clean-up |
ES2395022T3 (es) | 2003-09-19 | 2013-02-07 | Epitopix, Llc | Polipéptidos de Campylobacter y sus métodos de uso |
CA2597263C (fr) | 2005-02-14 | 2017-01-17 | Epitopix, Llc | Polypeptides et compositions immunisantes contenant des polypeptides gram-positifs et methodes d'utilisation |
US9932373B2 (en) | 2009-03-23 | 2018-04-03 | Epitopix, Llc | Polypeptides and immunizing compositions containing gram positive polypeptides and methods of use |
CN110251668A (zh) | 2010-11-30 | 2019-09-20 | 霍夫曼-拉罗奇有限公司 | 低亲和力血脑屏障受体抗体及其用途 |
CN105980562A (zh) | 2013-12-02 | 2016-09-28 | A·B·施里维斯 | 源于细菌表面受体蛋白的免疫原性组合物和疫苗 |
US10166280B2 (en) | 2016-06-08 | 2019-01-01 | Epitopix, Llc | Polypeptides and immunizing compositions containing Bacillus polypeptides and methods of use |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2227861B1 (fr) * | 1973-05-04 | 1976-07-02 | Anvar | |
US4220638A (en) * | 1978-10-12 | 1980-09-02 | Merck & Co., Inc. | Antigenic complex from N. Gonorrhoeae |
US4271147A (en) * | 1980-01-10 | 1981-06-02 | Behringwerke Aktiengesellschaft | Process for the isolation of membrane proteins from Neisseria meningitidis and vaccines containing same |
US4447547A (en) * | 1980-04-09 | 1984-05-08 | University Patents, Inc. | Immunoassay for measurement of reticulocytes, and immunoreactive reagents for use therein |
US4434156A (en) * | 1981-10-26 | 1984-02-28 | The Salk Institute For Biological Studies | Monoclonal antibodies specific for the human transferrin receptor glycoprotein |
US4681761A (en) * | 1985-10-24 | 1987-07-21 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University | Major iron-regulated protein of Neisseria gonorrhoeae and its use as vaccine |
WO1989007140A1 (fr) * | 1988-02-05 | 1989-08-10 | Commonwealth Scientific And Industrial Research Or | Systeme d'expression par genes (en particulier pour la proteine de rotavirus vp7) employant un peptide de signal etranger et eventuellement une sequence d'ancrage transmembrane |
FR2644346B1 (fr) * | 1989-03-20 | 1994-05-13 | Rhone Merieux | Vaccins contre les bacteries septicemiques, preparations d'antigenes de bacteries septicemiques, nouvelles bacteries et vecteurs pour la preparation de ces antigenes ou vaccins |
-
1990
- 1990-04-09 US US07/507,481 patent/US5292869A/en not_active Expired - Fee Related
- 1990-04-26 ES ES90906093T patent/ES2127184T3/es not_active Expired - Lifetime
- 1990-04-26 DK DK90906093T patent/DK0528787T3/da active
- 1990-04-26 EP EP90906093A patent/EP0528787B1/fr not_active Expired - Lifetime
- 1990-04-26 AU AU55261/90A patent/AU649950B2/en not_active Ceased
- 1990-04-26 DE DE69032806T patent/DE69032806T2/de not_active Expired - Fee Related
- 1990-04-26 AT AT90906093T patent/ATE173935T1/de not_active IP Right Cessation
- 1990-04-26 WO PCT/CA1990/000131 patent/WO1990012591A1/fr active IP Right Grant
- 1990-04-26 CA CA002051808A patent/CA2051808C/fr not_active Expired - Fee Related
- 1990-04-26 KR KR1019910701442A patent/KR100240974B1/ko not_active IP Right Cessation
- 1990-04-27 NZ NZ247967A patent/NZ247967A/en unknown
- 1990-04-27 IL IL9422890A patent/IL94228A/en not_active IP Right Cessation
- 1990-04-27 NZ NZ233471A patent/NZ233471A/en unknown
-
2001
- 2001-08-19 IL IL14497301A patent/IL144973A0/xx unknown
Also Published As
Publication number | Publication date |
---|---|
IL94228A0 (en) | 1991-01-31 |
NZ233471A (en) | 1993-11-25 |
ATE173935T1 (de) | 1998-12-15 |
DE69032806T2 (de) | 1999-08-05 |
US5292869A (en) | 1994-03-08 |
AU649950B2 (en) | 1994-06-09 |
AU5526190A (en) | 1990-11-16 |
CA2051808C (fr) | 1999-12-14 |
WO1990012591A1 (fr) | 1990-11-01 |
DE69032806D1 (de) | 1999-01-14 |
KR920700688A (ko) | 1992-08-10 |
KR100240974B1 (ko) | 2000-08-01 |
EP0528787A1 (fr) | 1993-03-03 |
EP0528787B1 (fr) | 1998-12-02 |
CA2051808A1 (fr) | 1990-10-28 |
NZ247967A (en) | 1995-02-24 |
ES2127184T3 (es) | 1999-04-16 |
IL144973A0 (en) | 2002-06-30 |
DK0528787T3 (da) | 1999-08-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0528787B1 (fr) | Procede permettant d'isoler et de purifier des proteines receptrices de transferrine et de lactoferrine a partir de bacteries et preparation de vaccins contenant de telles proteines | |
US5141743A (en) | Method for isolating and purifying transferrin and lactoferrin receptor proteins and vaccines containing the same | |
KR100242179B1 (ko) | 디스크 드라이브 데이타경로 보전 제어구조 | |
US6177085B1 (en) | Generation of immune response using immunogenic conjugate of molecules | |
Danve et al. | Transferrin-binding proteins isolated from Neisseria meningitidis elicit protective and bactericidal antibodies in laboratory animals | |
Frasch et al. | Protection against group B meningococcal disease. III. Immunogenicity of serotype 2 vaccines and specificity of protection in a guinea pig model. | |
Gilleland Jr et al. | Use of a purified outer membrane protein F (porin) preparation of Pseudomonas aeruginosa as a protective vaccine in mice | |
Munson et al. | Purification and comparison of outer membrane protein P2 from Haemophilus influenzae type b isolates. | |
Une et al. | Roles of V antigen in promoting virulence and immunity in yersiniae. | |
Verstreate et al. | Outer membrane proteins of Brucella abortus: isolation and characterization | |
Cryz Jr et al. | Protection against Pseudomonas aeruginosa infection in a murine burn wound sepsis model by passive transfer of antitoxin A, antielastase, and antilipopolysaccharide | |
US6558677B2 (en) | Vaccine against gram negative bacteria | |
Banerjee-Bhatnagar et al. | Expression of Neisseria meningitidis iron-regulated outer membrane proteins, including a 70-kilodalton transferrin receptor, and their potential for use as vaccines | |
Frasch | Role of protein serotype antigens in protection against disease due to Neisseria meningitidis | |
JP2004189751A (ja) | 非細胞性(Acellular)百日咳ワクチン及びその調製方法 | |
Craven et al. | Protection against group B meningococcal disease: evaluation of serotype 2 protein vaccines in a mouse bacteremia model | |
CA1251396A (fr) | Vaccins contenant des proteines ou des complexes peptidiques immunogenes | |
US4728639A (en) | Type-specific opsonic antibodies evoked with a synthetic peptide of streptococcal M protein conjugated to polylysine without adjuvant | |
IL127163A (en) | Vaccine which provides protective immunity against a bacterial pathogen | |
JP3335622B2 (ja) | 細菌からトランスフェリン及びラクトフェリン受容体タンパク質を分離及び精製する方法並びにこれらを含有するワクチンを調製する方法 | |
Beachey | Type-specific opsonic antibodies evoked with a synthetic peptide of streptococcal M protein conjugated to polylysine without adjuvant | |
CN104096224B (zh) | 一种增强流行性嗜血杆菌b型多糖蛋白结合物免疫原性的方法 | |
AU662116B2 (en) | Immunopotentiation of vaccines, particularly swine pleuropneumonia vaccines | |
LOEB et al. | Evaluating vaccine candidates for the prevention of otitis media | |
Green et al. | Overview: Bacterial Lipoproteins as Vaccines Candidates and Patent Considerations |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB20 | Patent renewed for 20 years | ||
EXP | Patent expired |