IL94143A0 - Renin-inhibiting dipeptides,a process for their preparation,compositions containing them and their use - Google Patents

Renin-inhibiting dipeptides,a process for their preparation,compositions containing them and their use

Info

Publication number
IL94143A0
IL94143A0 IL94143A IL9414390A IL94143A0 IL 94143 A0 IL94143 A0 IL 94143A0 IL 94143 A IL94143 A IL 94143A IL 9414390 A IL9414390 A IL 9414390A IL 94143 A0 IL94143 A0 IL 94143A0
Authority
IL
Israel
Prior art keywords
renin
preparation
compositions containing
dipeptides
inhibiting
Prior art date
Application number
IL94143A
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL94143A0 publication Critical patent/IL94143A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL94143A 1989-04-22 1990-04-20 Renin-inhibiting dipeptides,a process for their preparation,compositions containing them and their use IL94143A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3913290A DE3913290A1 (en) 1989-04-22 1989-04-22 RENIN-INHIBITING DI- AND TRIPEPTIDES, METHOD FOR THE PRODUCTION THEREOF, THE MEANS CONTAINING THEM AND THEIR USE

Publications (1)

Publication Number Publication Date
IL94143A0 true IL94143A0 (en) 1991-01-31

Family

ID=6379231

Family Applications (1)

Application Number Title Priority Date Filing Date
IL94143A IL94143A0 (en) 1989-04-22 1990-04-20 Renin-inhibiting dipeptides,a process for their preparation,compositions containing them and their use

Country Status (15)

Country Link
EP (1) EP0394829A1 (en)
JP (1) JPH02295999A (en)
KR (1) KR900016256A (en)
CN (1) CN1047085A (en)
AU (1) AU622014B2 (en)
CA (1) CA2015071A1 (en)
CS (1) CS198090A2 (en)
DE (1) DE3913290A1 (en)
FI (1) FI901958A0 (en)
HU (1) HU204070B (en)
IL (1) IL94143A0 (en)
MA (1) MA21811A1 (en)
NO (1) NO901758L (en)
PT (1) PT93798A (en)
ZA (1) ZA902996B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8929070D0 (en) * 1989-12-22 1990-02-28 Fujisawa Pharmaceutical Co Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
WO1994006755A1 (en) * 1992-09-18 1994-03-31 Japan Tobacco Inc. Alcohol derivative having renin-inhibiting activity and use thereof
US5554641A (en) * 1995-03-20 1996-09-10 Horwell; David C. Nonpeptides as tachykinin antagonists

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0163237A3 (en) * 1984-05-29 1988-04-27 Merck & Co. Inc. Di- and tri-peptidal renin inhibitors
US4657931A (en) * 1985-05-15 1987-04-14 G. D. Searle & Co. N-(acyldipeptidyl)-aminoglycols
ZA87563B (en) * 1986-02-03 1987-09-30 Squibb & Sons Inc N-heterocyclic alcohol renin inhibitors
DE3627877A1 (en) * 1986-07-30 1988-02-04 Hoechst Ag RENINE-INHIBITING DI- AND TRIPEPTIDES, METHOD FOR THE PRODUCTION THEREOF, THESE AGENTS AND THEIR USE
DE3721855A1 (en) * 1987-03-12 1988-09-22 Merck Patent Gmbh AMINO ACID DERIVATIVES
DE3717631A1 (en) * 1987-05-26 1988-12-15 Merck Patent Gmbh AMINO ACID DERIVATIVES
DE3732971A1 (en) * 1987-09-30 1989-04-20 Hoechst Ag RENINE INHIBITING DIPEPTIDES, METHOD FOR THE PRODUCTION THEREOF, THE AGENTS CONTAINING THEM AND THEIR USE

Also Published As

Publication number Publication date
AU5371190A (en) 1990-11-01
PT93798A (en) 1990-11-20
HU204070B (en) 1991-11-28
HU902499D0 (en) 1990-08-28
DE3913290A1 (en) 1990-10-25
JPH02295999A (en) 1990-12-06
AU622014B2 (en) 1992-03-26
CS198090A2 (en) 1991-08-13
CN1047085A (en) 1990-11-21
NO901758L (en) 1990-10-23
MA21811A1 (en) 1990-12-31
NO901758D0 (en) 1990-04-20
CA2015071A1 (en) 1990-10-22
FI901958A0 (en) 1990-04-19
KR900016256A (en) 1990-11-13
EP0394829A1 (en) 1990-10-31
ZA902996B (en) 1990-12-28

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