IL87912A0 - Renin-inhibiting dipeptides,a process for the preparation thereof and pharmaceutical compositions containing them - Google Patents

Renin-inhibiting dipeptides,a process for the preparation thereof and pharmaceutical compositions containing them

Info

Publication number
IL87912A0
IL87912A0 IL87912A IL8791288A IL87912A0 IL 87912 A0 IL87912 A0 IL 87912A0 IL 87912 A IL87912 A IL 87912A IL 8791288 A IL8791288 A IL 8791288A IL 87912 A0 IL87912 A0 IL 87912A0
Authority
IL
Israel
Prior art keywords
renin
preparation
pharmaceutical compositions
compositions containing
dipeptides
Prior art date
Application number
IL87912A
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL87912A0 publication Critical patent/IL87912A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06078Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IL87912A 1987-09-30 1988-09-27 Renin-inhibiting dipeptides,a process for the preparation thereof and pharmaceutical compositions containing them IL87912A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873732971 DE3732971A1 (en) 1987-09-30 1987-09-30 RENINE INHIBITING DIPEPTIDES, METHOD FOR THE PRODUCTION THEREOF, THE AGENTS CONTAINING THEM AND THEIR USE

Publications (1)

Publication Number Publication Date
IL87912A0 true IL87912A0 (en) 1989-03-31

Family

ID=6337246

Family Applications (1)

Application Number Title Priority Date Filing Date
IL87912A IL87912A0 (en) 1987-09-30 1988-09-27 Renin-inhibiting dipeptides,a process for the preparation thereof and pharmaceutical compositions containing them

Country Status (13)

Country Link
EP (1) EP0310015A3 (en)
JP (1) JPH01121258A (en)
KR (1) KR890005146A (en)
AU (1) AU624579B2 (en)
DE (1) DE3732971A1 (en)
DK (1) DK543788A (en)
FI (1) FI884455A (en)
HU (1) HU203118B (en)
IL (1) IL87912A0 (en)
NO (1) NO884324L (en)
NZ (1) NZ226361A (en)
PT (1) PT88622B (en)
ZA (1) ZA887264B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL87614A0 (en) * 1987-09-16 1989-01-31 Abbott Lab Peptidylheterocycles
DE3804793A1 (en) * 1988-02-16 1989-08-24 Hoechst Ag RENIN-INHIBITING AMINOSAUTE DERIVATIVES
DE3814325A1 (en) * 1988-04-28 1989-11-09 Merck Patent Gmbh AMINOSAEUREDERIVATE
DE3841520A1 (en) * 1988-12-09 1990-06-13 Hoechst Ag ENZYME-INFRINGING DERIVATIVES OF DIPEPTIDES, METHOD FOR THE PRODUCTION THEREOF, METHODS CONTAINING THEM AND THEIR USE
DE3913290A1 (en) * 1989-04-22 1990-10-25 Hoechst Ag RENIN-INHIBITING DI- AND TRIPEPTIDES, METHOD FOR THE PRODUCTION THEREOF, THE MEANS CONTAINING THEM AND THEIR USE
TW225540B (en) * 1990-06-28 1994-06-21 Shionogi & Co
US5554641A (en) * 1995-03-20 1996-09-10 Horwell; David C. Nonpeptides as tachykinin antagonists
JP4696352B2 (en) * 2000-11-30 2011-06-08 トヨタ自動車株式会社 Vehicle power supply

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3538749A1 (en) * 1985-10-31 1987-05-07 Merck Patent Gmbh PEPTIDE
DE3601248A1 (en) * 1986-01-17 1987-07-23 Hoechst Ag SUBSTITUTED 4-AMINO-3-HYDROXYBUTTERIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, THESE AGENTS AND THEIR USE
ZA87563B (en) * 1986-02-03 1987-09-30 Squibb & Sons Inc N-heterocyclic alcohol renin inhibitors
DE3627877A1 (en) * 1986-07-30 1988-02-04 Hoechst Ag RENINE-INHIBITING DI- AND TRIPEPTIDES, METHOD FOR THE PRODUCTION THEREOF, THESE AGENTS AND THEIR USE
WO1988003022A1 (en) * 1986-10-31 1988-05-05 Pfizer Inc. Relatively low molecular weight polypeptides as renin inhibitors
NL8800100A (en) * 1987-01-21 1988-08-16 Sandoz Ag NEW PEPTIDE DERIVATIVES AND METHODS FOR PREPARING AND USING THESE DERIVATIVES.

Also Published As

Publication number Publication date
HU203118B (en) 1991-05-28
DK543788A (en) 1989-03-31
DE3732971A1 (en) 1989-04-20
NO884324D0 (en) 1988-09-29
ZA887264B (en) 1989-06-28
NO884324L (en) 1989-03-31
FI884455A (en) 1989-03-31
DK543788D0 (en) 1988-09-29
EP0310015A3 (en) 1992-05-20
JPH01121258A (en) 1989-05-12
EP0310015A2 (en) 1989-04-05
AU624579B2 (en) 1992-06-18
KR890005146A (en) 1989-05-13
FI884455A0 (en) 1988-09-28
PT88622A (en) 1989-07-31
HUT48278A (en) 1989-05-29
NZ226361A (en) 1991-12-23
PT88622B (en) 1993-07-30
AU2295988A (en) 1989-06-29

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