IL92425A0 - Alpha-d-glucofuranose derivatives,pharmaceutical compositions containing the same and processes for the preparation thereof - Google Patents

Alpha-d-glucofuranose derivatives,pharmaceutical compositions containing the same and processes for the preparation thereof

Info

Publication number
IL92425A0
IL92425A0 IL92425A IL9242589A IL92425A0 IL 92425 A0 IL92425 A0 IL 92425A0 IL 92425 A IL92425 A IL 92425A IL 9242589 A IL9242589 A IL 9242589A IL 92425 A0 IL92425 A0 IL 92425A0
Authority
IL
Israel
Prior art keywords
alpha
processes
preparation
same
pharmaceutical compositions
Prior art date
Application number
IL92425A
Other languages
English (en)
Original Assignee
Greenwich Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Greenwich Pharma filed Critical Greenwich Pharma
Publication of IL92425A0 publication Critical patent/IL92425A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/08Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to sulfur, selenium or tellurium
    • C07H5/10Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to sulfur, selenium or tellurium to sulfur
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04Cyclic acetals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/12Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/14Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
IL92425A 1989-01-09 1989-11-23 Alpha-d-glucofuranose derivatives,pharmaceutical compositions containing the same and processes for the preparation thereof IL92425A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/294,838 US4996195A (en) 1989-01-09 1989-01-09 Derivatives of α,D-glucofuranose or α,D-allofuranose and intermediates for preparing these derivatives

Publications (1)

Publication Number Publication Date
IL92425A0 true IL92425A0 (en) 1990-07-26

Family

ID=23135159

Family Applications (1)

Application Number Title Priority Date Filing Date
IL92425A IL92425A0 (en) 1989-01-09 1989-11-23 Alpha-d-glucofuranose derivatives,pharmaceutical compositions containing the same and processes for the preparation thereof

Country Status (9)

Country Link
US (1) US4996195A (no)
EP (1) EP0379397A3 (no)
JP (1) JPH02262586A (no)
KR (1) KR900011784A (no)
AU (1) AU616335B2 (no)
CA (1) CA2007308A1 (no)
IL (1) IL92425A0 (no)
NO (1) NO173873C (no)
ZA (1) ZA899026B (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5298494A (en) * 1989-01-09 1994-03-29 Greenwich Pharmaceuticals Incorporated Monosaccharides having anti-proliferation and anti-inflammatory activity, compositions and uses thereof
US5010058A (en) * 1989-06-22 1991-04-23 501 Greenwich Pharmaceuticals Incorporated 3,5,6-substituted derivatives of 1,2-O-isopropylidene-α,D-glucofuranose and intermediates for preparing these derivatives
IL99454A0 (en) * 1990-09-12 1992-08-18 Greenwich Pharma Monosaccharide derivatives and pharmaceutical compositions containing the same
IL100833A0 (en) * 1991-02-20 1992-09-06 Greenwich Pharma Method for synthesis of ethereally substituted blocked monosaccharides
GB9125002D0 (en) * 1991-11-25 1992-01-22 Ici Plc Azole derivatives
US5360792A (en) * 1991-12-20 1994-11-01 Greenwich Pharmaceuticals Incorporated Anti-proliferative and anti-inflammatory compounds: 5- or 6-deoxy hexose monosaccharides having a saturated nitrogen-containing heterocycle at the 5- or 6-position bound through the nitrogen atom
FR2694753B1 (fr) * 1992-07-09 1994-12-23 Picardie Jules Verne Universit Procédés de synthèse spécifique de nouveaux aminothioéthers par substitution des sites hydroxylés sur des molécules mono ou polyhydroxylées, produits obtenus par ces procédés et leurs applications.
US5360794A (en) * 1992-08-03 1994-11-01 Medicarb Inc. Disubstituted and deoxy disubstituted derivatives of α-D-mannofuranosides and β-L-gulofuranosides having anti-inflammatory and anti-proliferative activity
US5367062A (en) * 1992-08-21 1994-11-22 Medicarb Inc. Disubstituted and deoxydisubstituted derivatives of α-d-lyxofuranosides having anti-inflammatory and anti-proliferative activity
US5432163A (en) * 1992-11-13 1995-07-11 Greenwich Pharmaceuticals Incorporated Anti-proliferative and anti-inflammatory compounds: derivatives of pentose monosaccharides
CA2164827A1 (en) * 1993-06-11 1994-12-22 David S. Thomson Immunomodulatory, anti-inflammatory, and anti-proliferative compounds: 5,6-dideoxy, 5-amino derivatives of idose and 6-deoxy, 6-amino derivatives of glucose
US6329344B1 (en) 1998-10-22 2001-12-11 Ranbaxy Laboratories Limited Derivatives of monosaccharides as cell adhesion inhibitors
IN190975B (no) * 1999-01-15 2003-09-06 Ranbaxy Lab Ltd
WO2002098892A1 (en) * 2001-06-07 2002-12-12 Santaris Pharma A/S Improved synthesis of allofuranose
WO2006024926A1 (en) * 2004-09-02 2006-03-09 Ranbaxy Laboratories Limited Monosaccharide derivatives
EP1902063A2 (en) * 2004-12-22 2008-03-26 Ranbaxy Laboratories Limited Derivatives of pentose monosaccharides as anti-inflammatory compounds
US20080114031A1 (en) * 2006-03-29 2008-05-15 Sattigeri Viswajanani J Monosaccharide derivatives
EP1864992A2 (en) * 2006-05-30 2007-12-12 Ranbaxy Laboratories, Ltd. Monosaccharide derivatives
US20080300196A1 (en) * 2006-10-03 2008-12-04 Ashwani Kumar Verma Monosaccharide derivatives

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2461478A (en) * 1946-12-18 1949-02-08 Gen Aniline & Film Corp Gelatin subbing compositions having antistatic properties
US2875194A (en) * 1955-10-05 1959-02-24 American Cyanamid Co Derivatives of 5-amino-d-ribofuranose
US2960452A (en) * 1958-07-14 1960-11-15 Miles Lab Preparation of diacetone 2-keto-gulonic acid
US3586664A (en) * 1969-03-19 1971-06-22 Eisai Co Ltd Xylose derivatives and preparation thereof
US3832355A (en) * 1970-05-13 1974-08-27 Hoffmann La Roche Catalytic oxidation process
US4032650A (en) * 1972-09-15 1977-06-28 A.E.C. Societe De Chimie Organique Et Biologique Method of treating fatigue by administering a gulonic acid salt
US4016261A (en) * 1973-03-01 1977-04-05 Strategic Medical Research Corporation Therapeutic composition and method of therapeutically treating warm blooded animals therewith
USRE30379E (en) * 1973-03-01 1980-08-19 Strategic Medical Research Corp. Ethereal monosubstitutions of monosaccharide derivatives
US3939146A (en) * 1973-03-01 1976-02-17 Strategic Medical Research Corporation Novel ethereal monosubstitutions of monosaccharide derivatives
USRE32268E (en) * 1973-03-01 1986-10-21 Strategic Medical Research Corp. Therapeutic composition and method of therapeutically treating warm blooded animals therewith
US3965262A (en) * 1973-03-01 1976-06-22 Strategic Medical Research Corporation Method of enhancing learning and/or memory in warm blooded animals
US3939145A (en) * 1973-03-01 1976-02-17 Strategic Medical Research Corporation Novel ethereally monosubstituted monosaccharides
US4017608A (en) * 1973-12-14 1977-04-12 Strategic Medical Research Corporation Therapeutic composition and method of therapeutically treating warm blooded animals therewith
IN141230B (no) * 1973-12-14 1977-02-05 Strategic Medical Res Corp
US4056322A (en) * 1973-12-14 1977-11-01 Strategic Medical Research Corporation Preparation of ethers of monosaccharides
US4010275A (en) * 1975-03-18 1977-03-01 Ciba-Geigy Corporation Treatment of osteoarthritis
GB1589916A (en) * 1976-11-16 1981-05-20 Prodotti Antibiotici Spa Glucofuranose derivatives
USRE30354E (en) * 1978-02-17 1980-07-29 Strategic Medical Research Corp. Novel ethereally monosubstituted monosaccharides
DE2830469A1 (de) * 1978-07-11 1980-01-24 Bayer Ag Herstellung von l-desoxy-nojirimycin und n-substituierten derivaten
US4735934A (en) * 1981-02-17 1988-04-05 Greenwich Pharmaceuticals Incorporated Method of therapeutically treating a warm blooded animal afflicted with an autoimmune disease
US4738953A (en) * 1981-02-17 1988-04-19 Greenwich Pharmaceuticals Incorporated Method of therapeutically treating a warm blooded animal afflicted with an autoimmune disease and a synergistic composition therefor
US4554349A (en) * 1983-10-11 1985-11-19 Merck & Co., Inc. Aralkyl and aralkenyl glycosides as inhibitors of antigen-specific T-cell proliferation
JPS6222703A (ja) * 1985-07-22 1987-01-30 Ss Pharmaceut Co Ltd 植物生長調節剤

Also Published As

Publication number Publication date
NO895067L (no) 1990-07-10
EP0379397A2 (en) 1990-07-25
EP0379397A3 (en) 1992-11-04
US4996195A (en) 1991-02-26
NO173873C (no) 1994-02-16
AU4764890A (en) 1990-08-09
JPH02262586A (ja) 1990-10-25
NO895067D0 (no) 1989-12-15
AU616335B2 (en) 1991-10-24
KR900011784A (ko) 1990-08-02
ZA899026B (en) 1990-12-28
CA2007308A1 (en) 1990-07-09
NO173873B (no) 1993-11-08

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