IL90652A - 8,9-annelated-b-carboline and -3,4-dihydro-b- carboline derivatives, their preparation and pharmaceutical compositions containing them - Google Patents

8,9-annelated-b-carboline and -3,4-dihydro-b- carboline derivatives, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL90652A
IL90652A IL90652A IL9065289A IL90652A IL 90652 A IL90652 A IL 90652A IL 90652 A IL90652 A IL 90652A IL 9065289 A IL9065289 A IL 9065289A IL 90652 A IL90652 A IL 90652A
Authority
IL
Israel
Prior art keywords
carboline
annelated
dihydro
preparation
pharmaceutical compositions
Prior art date
Application number
IL90652A
Other languages
English (en)
Other versions
IL90652A0 (en
Original Assignee
Duphar Int Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar Int Res filed Critical Duphar Int Res
Publication of IL90652A0 publication Critical patent/IL90652A0/xx
Publication of IL90652A publication Critical patent/IL90652A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/16—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL90652A 1988-06-20 1989-06-19 8,9-annelated-b-carboline and -3,4-dihydro-b- carboline derivatives, their preparation and pharmaceutical compositions containing them IL90652A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8801565 1988-06-20
NL8900136 1989-01-20

Publications (2)

Publication Number Publication Date
IL90652A0 IL90652A0 (en) 1990-01-18
IL90652A true IL90652A (en) 1993-08-18

Family

ID=26646394

Family Applications (1)

Application Number Title Priority Date Filing Date
IL90652A IL90652A (en) 1988-06-20 1989-06-19 8,9-annelated-b-carboline and -3,4-dihydro-b- carboline derivatives, their preparation and pharmaceutical compositions containing them

Country Status (8)

Country Link
US (1) US5332746A (de)
EP (1) EP0347980A1 (de)
JP (1) JPH0245485A (de)
AU (1) AU628059B2 (de)
CA (1) CA1338190C (de)
DK (1) DK169731B1 (de)
IL (1) IL90652A (de)
NZ (1) NZ229587A (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0357122A3 (de) * 1988-08-29 1991-10-23 Duphar International Research B.V Verwendung von Beta-Carbolinen und deren bio-isosterischen Benzofuran- und Benzothiophenanalogen zur Herstellung eines Arzneimittels mit cytostatischer Wirkung
US5663178A (en) * 1995-02-06 1997-09-02 Eli Lilly And Company Tetrahydro-beta carbolines
DE60014079T2 (de) * 1999-06-15 2006-03-02 Bristol-Myers Squibb Pharma Co., Wilmington Substituierte heterocyclisch kondensierte Gammacarboline
US8563567B2 (en) 2009-12-30 2013-10-22 Arqule, Inc. Substituted heterocyclic compounds
US9907786B2 (en) 2014-10-21 2018-03-06 Ions Pharmaceutical S.À R.L. Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof
US10092550B2 (en) 2014-10-21 2018-10-09 Ions Pharmaceutical S.À R.L. Therapeutic compositions containing curcumin, harmine, and isovanillin components, and methods of use thereof
US10947253B2 (en) 2019-08-05 2021-03-16 Ankh Life Sciences Limited Fused polycyclic dimers
US12129265B2 (en) 2020-07-21 2024-10-29 Ankh Life Sciences Limited Therapeutic agents and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES273769A1 (es) * 1961-01-18 1962-06-01 Geigy Ag J R Procedimiento para la preparaciën de nuevos derivados de amidas de acido beta-carbolin-carboxilico
DD129791A5 (de) * 1976-04-13 1978-02-08 Synthelabo Verfahren zur herstellung von naphtyridinderivaten
US4200638A (en) * 1977-09-30 1980-04-29 Omnium Chimique Societe Anonyme Indole derivatives and therapeutically acting drugs
NL189463C (nl) * 1978-12-28 1993-04-16 Omnichem Sa Indolonaftyridinederivaten, werkwijze voor het bereiden daarvan en geneesmiddel voor de behandeling van cardiocirculatore en cerebrovasculaire aandoeningen.
LU84664A1 (fr) * 1983-02-25 1984-11-08 Onmichem S A Alkyl-4-indolonaphtyridines et leur application therapeutique
EP0300541B1 (de) * 1987-07-20 1996-03-27 Duphar International Research B.V 8,9-Anellierte 1,2,3,4-Tetrahydro-beta-carbolin-Derivate
ZA889251B (en) * 1987-12-14 1989-08-30 Duphar Int Res 8,9-annelated-beta-carbolines and 8,9-annelated-3,4-dihydro-beta-carbolines
EP0357122A3 (de) * 1988-08-29 1991-10-23 Duphar International Research B.V Verwendung von Beta-Carbolinen und deren bio-isosterischen Benzofuran- und Benzothiophenanalogen zur Herstellung eines Arzneimittels mit cytostatischer Wirkung

Also Published As

Publication number Publication date
IL90652A0 (en) 1990-01-18
NZ229587A (en) 1991-05-28
DK294989A (da) 1989-12-21
DK169731B1 (da) 1995-01-30
AU628059B2 (en) 1992-09-10
DK294989D0 (da) 1989-06-15
CA1338190C (en) 1996-03-26
EP0347980A1 (de) 1989-12-27
AU3650189A (en) 1989-12-21
JPH0245485A (ja) 1990-02-15
US5332746A (en) 1994-07-26

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Legal Events

Date Code Title Description
RH Patent void