IL89827A0 - Phosphoramidite reagent for chemical synthesis of modified dna - Google Patents
Phosphoramidite reagent for chemical synthesis of modified dnaInfo
- Publication number
- IL89827A0 IL89827A0 IL89827A IL8982789A IL89827A0 IL 89827 A0 IL89827 A0 IL 89827A0 IL 89827 A IL89827 A IL 89827A IL 8982789 A IL8982789 A IL 8982789A IL 89827 A0 IL89827 A0 IL 89827A0
- Authority
- IL
- Israel
- Prior art keywords
- chemical synthesis
- modified dna
- phosphoramidite reagent
- phosphoramidite
- reagent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/12—Triazine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/178,153 US5324831A (en) | 1988-04-06 | 1988-04-06 | Phosphoramidite reagent for chemical synthesis of modified DNA |
Publications (1)
Publication Number | Publication Date |
---|---|
IL89827A0 true IL89827A0 (en) | 1989-12-15 |
Family
ID=22651417
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL89827A IL89827A0 (en) | 1988-04-06 | 1989-04-03 | Phosphoramidite reagent for chemical synthesis of modified dna |
Country Status (6)
Country | Link |
---|---|
US (1) | US5324831A (ja) |
JP (1) | JPH0692435B2 (ja) |
AU (1) | AU625295B2 (ja) |
CA (1) | CA1330960C (ja) |
IL (1) | IL89827A0 (ja) |
WO (1) | WO1989009779A1 (ja) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5585481A (en) * | 1987-09-21 | 1996-12-17 | Gen-Probe Incorporated | Linking reagents for nucleotide probes |
US6031091A (en) * | 1987-09-21 | 2000-02-29 | Gen-Probe Incorporated | Non-nucleotide linking reagents for nucleotide probes |
ATE154246T1 (de) * | 1990-07-27 | 1997-06-15 | Isis Pharmaceuticals Inc | Nuklease resistente, pyrimidin modifizierte oligonukleotide, die die gen-expression detektieren und modulieren |
US5574146A (en) * | 1994-08-30 | 1996-11-12 | Beckman Instruments, Inc. | Oligonucleotide synthesis with substituted aryl carboxylic acids as activators |
US6562798B1 (en) | 1998-06-05 | 2003-05-13 | Dynavax Technologies Corp. | Immunostimulatory oligonucleotides with modified bases and methods of use thereof |
US6184347B1 (en) | 1998-11-19 | 2001-02-06 | Agilent Technologies Inc. | Minimization of blooming in high-density arrays by using reactive wash reagents |
CA2370478A1 (en) | 1999-03-24 | 2000-09-28 | Serge L. Beaucage | N-acylphosphoramidites and their use in oligonucleotide synthesis |
US20030072689A1 (en) * | 2001-08-15 | 2003-04-17 | Third Wave Technologies, Inc. | Polymer synthesizer |
US7435390B2 (en) * | 2001-01-26 | 2008-10-14 | Third Wave Technologies, Inc. | Nucleic acid synthesizers |
US6932943B1 (en) | 2001-01-26 | 2005-08-23 | Third Wave Technologies | Nucleic acid synthesizers |
US20080261220A1 (en) * | 2000-11-30 | 2008-10-23 | Third Wave Technologies, Inc. | Nucleic Acid Detection Assays |
AU2002353001A1 (en) * | 2001-12-03 | 2003-06-17 | The Government Of The United States Of America, Represented By The Secretary Of The Department Of He | Thermolabile hydroxyl protecting groups and methods of use |
US20070207973A1 (en) * | 2002-09-24 | 2007-09-06 | Koronis Pharmaceuticals, Incorporated | 1,3,5-Triazines for Treatment of Viral Diseases |
WO2004028454A2 (en) * | 2002-09-24 | 2004-04-08 | Koronis Pharmaceuticals, Incorporated | 1, 3, 5-triazines for treatment of viral diseases |
WO2006065751A2 (en) * | 2004-12-13 | 2006-06-22 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Cpg oligonucleotide prodrugs, compositions thereof and associated therapeutic methods |
US7700567B2 (en) | 2005-09-29 | 2010-04-20 | Supergen, Inc. | Oligonucleotide analogues incorporating 5-aza-cytosine therein |
US7829735B2 (en) * | 2007-10-26 | 2010-11-09 | Northwestern University | Universal phosphoramidite for preparation of modified biomolecules and surfaces |
MY163296A (en) | 2011-08-30 | 2017-09-15 | Astex Pharmaceuticals Inc | Drug formulations |
MX2018000016A (es) | 2015-07-02 | 2019-01-31 | Otsuka Pharma Co Ltd | Composiciones farmaceuticas liofilizadas. |
EP3661522A2 (en) | 2017-08-03 | 2020-06-10 | Otsuka Pharmaceutical Co., Ltd. | Drug compound and purification methods thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3817982A (en) * | 1971-12-29 | 1974-06-18 | Syntex Inc | 2{40 ,3{40 -unsaturated nucleosides and method of making |
US4058602A (en) * | 1976-08-09 | 1977-11-15 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Synthesis, structure, and antitumor activity of 5,6-dihydro-5-azacytidine |
US4458066A (en) * | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
US4668777A (en) * | 1981-03-27 | 1987-05-26 | University Patents, Inc. | Phosphoramidite nucleoside compounds |
US4849513A (en) * | 1983-12-20 | 1989-07-18 | California Institute Of Technology | Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups |
US4843066A (en) * | 1986-11-27 | 1989-06-27 | Nippon Zoki Pharmaceutical Co., Ltd. | Novel adenosine derivatives and pharmaceutical composition containing them as an active ingredient |
-
1988
- 1988-04-06 US US07/178,153 patent/US5324831A/en not_active Expired - Lifetime
-
1989
- 1989-04-03 IL IL89827A patent/IL89827A0/xx unknown
- 1989-04-05 CA CA000595701A patent/CA1330960C/en not_active Expired - Fee Related
- 1989-04-06 WO PCT/US1989/001395 patent/WO1989009779A1/en unknown
- 1989-04-06 AU AU33681/89A patent/AU625295B2/en not_active Ceased
- 1989-04-06 JP JP1504376A patent/JPH0692435B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU3368189A (en) | 1989-11-03 |
US5324831A (en) | 1994-06-28 |
WO1989009779A1 (en) | 1989-10-19 |
JPH03502577A (ja) | 1991-06-13 |
AU625295B2 (en) | 1992-07-09 |
CA1330960C (en) | 1994-07-26 |
JPH0692435B2 (ja) | 1994-11-16 |
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