IL87992A0 - R-n-(1-azabicyclo(2.2.2)oct-3-yl)benzamide and thiobenzamide derivatives,pharmaceutical compositions containing the same and processes for the preparation thereof - Google Patents

R-n-(1-azabicyclo(2.2.2)oct-3-yl)benzamide and thiobenzamide derivatives,pharmaceutical compositions containing the same and processes for the preparation thereof

Info

Publication number
IL87992A0
IL87992A0 IL87992A IL8799288A IL87992A0 IL 87992 A0 IL87992 A0 IL 87992A0 IL 87992 A IL87992 A IL 87992A IL 8799288 A IL8799288 A IL 8799288A IL 87992 A0 IL87992 A0 IL 87992A0
Authority
IL
Israel
Prior art keywords
thiobenzamide
azabicyclo
benzamide
oct
derivatives
Prior art date
Application number
IL87992A
Other languages
English (en)
Original Assignee
Delalande Sa
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande Sa, Robins Co Inc A H filed Critical Delalande Sa
Publication of IL87992A0 publication Critical patent/IL87992A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL87992A 1987-10-16 1988-10-10 R-n-(1-azabicyclo(2.2.2)oct-3-yl)benzamide and thiobenzamide derivatives,pharmaceutical compositions containing the same and processes for the preparation thereof IL87992A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP87402321A EP0311724A1 (fr) 1987-10-16 1987-10-16 R-N-(1-azabicyclo[2.2.2]oct-3-yl) benzamides et thiobenzamides anxiolytiques

Publications (1)

Publication Number Publication Date
IL87992A0 true IL87992A0 (en) 1989-06-30

Family

ID=8198265

Family Applications (1)

Application Number Title Priority Date Filing Date
IL87992A IL87992A0 (en) 1987-10-16 1988-10-10 R-n-(1-azabicyclo(2.2.2)oct-3-yl)benzamide and thiobenzamide derivatives,pharmaceutical compositions containing the same and processes for the preparation thereof

Country Status (11)

Country Link
EP (1) EP0311724A1 (fr)
JP (1) JPH01199969A (fr)
KR (1) KR890006640A (fr)
AU (1) AU618027B2 (fr)
CA (1) CA1322552C (fr)
DK (1) DK576188A (fr)
IL (1) IL87992A0 (fr)
NZ (1) NZ226581A (fr)
PH (1) PH25858A (fr)
PT (1) PT88759B (fr)
ZA (1) ZA887601B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820715A (en) * 1984-06-28 1989-04-11 Bristol-Myers Company Anti-emetic quinuclidinyl benzamides
WO1991007402A1 (fr) * 1989-11-17 1991-05-30 Pfizer Inc. Amides et esters azabicyliques antagonistes du recepteur de 5-ht¿3?
US5446050A (en) * 1989-11-17 1995-08-29 Pfizer Inc. Azabicyclo amides and esters as 5-HT3 receptor antagonists
US5192770A (en) * 1990-12-07 1993-03-09 Syntex (U.S.A.) Inc. Serotonergic alpha-oxoacetamides
ZA92278B (en) * 1991-02-01 1992-10-28 Akzo Nv 3-quinuclidine derivatives
GB0310867D0 (en) 2003-05-12 2003-06-18 Novartis Ag Organic compounds
CA2840480A1 (fr) 2011-06-30 2013-01-03 Toray Industries, Inc. Agent antiprurigineux

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4093734A (en) * 1975-11-03 1978-06-06 Boehringer Ingelheim Gmbh Amino-benzoic acid amides
FR2531083B1 (fr) * 1982-06-29 1986-11-28 Sandoz Sa Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
FR2529548A1 (fr) * 1982-07-02 1984-01-06 Delalande Sa Nouveaux derives de l'amino-3 quinuclidine, leur procede et leur application en therapeutique
JPS5967284A (ja) * 1982-07-13 1984-04-16 サンド・アクチエンゲルシヤフト インドリルカルボン酸ピペリジルエステル誘導体
US4593034A (en) * 1984-04-06 1986-06-03 A. H. Robins Company, Inc. 2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamides and thiobenzamides
US4605652A (en) * 1985-02-04 1986-08-12 A. H. Robins Company, Inc. Method of enhancing memory or correcting memory deficiency with arylamido (and arylthioamido)-azabicycloalkanes
US4870181A (en) * 1985-02-04 1989-09-26 A. H. Robins Company, Incorporated Process for the preparation of 2-alkoxy-N-(1-azabicyclo[2.2.2])octan-3-yl)aminobenzamides
US4722834A (en) * 1986-03-05 1988-02-02 A. H. Robins Company, Incorporated Method of using 2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamide-N-oxides to control emesis caused by anticancer drugs
DE3780276T2 (de) * 1986-12-16 1993-02-25 Robins Co Inc A H Angstloesende n-(1-azabicyclo(2.2.2)oct-3-yl)benzamide und -thiobenzamide.
FR2610323B1 (fr) * 1987-02-04 1989-06-23 Delalande Sa Enantiomeres de configuration absolue s de derives amide de l'amino-3 quinuclidine, leur procede de preparation et leur application en therapeutique

Also Published As

Publication number Publication date
KR890006640A (ko) 1989-06-15
PH25858A (en) 1991-12-02
DK576188D0 (da) 1988-10-14
PT88759B (pt) 1992-12-31
CA1322552C (fr) 1993-09-28
AU2374988A (en) 1989-04-20
NZ226581A (en) 1991-04-26
DK576188A (da) 1989-04-17
ZA887601B (en) 1989-07-26
JPH01199969A (ja) 1989-08-11
AU618027B2 (en) 1991-12-12
EP0311724A1 (fr) 1989-04-19

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