IL86438A - Cyclic anticoagulant peptides - Google Patents

Cyclic anticoagulant peptides

Info

Publication number
IL86438A
IL86438A IL86438A IL8643888A IL86438A IL 86438 A IL86438 A IL 86438A IL 86438 A IL86438 A IL 86438A IL 8643888 A IL8643888 A IL 8643888A IL 86438 A IL86438 A IL 86438A
Authority
IL
Israel
Prior art keywords
cyclic
anticoagulant peptides
anticoagulant
peptides
chem
Prior art date
Application number
IL86438A
Other languages
English (en)
Other versions
IL86438A0 (en
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of IL86438A0 publication Critical patent/IL86438A0/xx
Publication of IL86438A publication Critical patent/IL86438A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/815Protease inhibitors from leeches, e.g. hirudin, eglin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
IL86438A 1987-05-21 1988-05-19 Cyclic anticoagulant peptides IL86438A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5316987A 1987-05-21 1987-05-21

Publications (2)

Publication Number Publication Date
IL86438A0 IL86438A0 (en) 1988-11-15
IL86438A true IL86438A (en) 1992-11-15

Family

ID=21982364

Family Applications (1)

Application Number Title Priority Date Filing Date
IL86438A IL86438A (en) 1987-05-21 1988-05-19 Cyclic anticoagulant peptides

Country Status (17)

Country Link
EP (1) EP0291982B1 (de)
JP (1) JP2858249B2 (de)
KR (1) KR970010926B1 (de)
CN (1) CN88103015A (de)
AT (1) ATE91490T1 (de)
AU (1) AU613627B2 (de)
CA (1) CA1340646C (de)
DE (1) DE3882279T2 (de)
DK (1) DK278488A (de)
ES (1) ES2058176T3 (de)
FI (1) FI89063C (de)
HU (1) HU198513B (de)
IL (1) IL86438A (de)
NO (1) NO882238L (de)
NZ (1) NZ224678A (de)
PT (1) PT87536B (de)
ZA (1) ZA883443B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192745A (en) * 1987-05-21 1993-03-09 Merrell Dow Pharmaceuticals Inc. Cyclic anticoagulant peptides
US5236898A (en) * 1987-05-21 1993-08-17 Merrell Dow Pharmaceuticals Inc. Cyclic anticoagulant peptides
NZ228995A (en) * 1988-05-10 1992-03-26 Merrell Dow Pharma Hirudin peptide derivatives and pharmaceutical compositions
US5196404B1 (en) * 1989-08-18 1996-09-10 Biogen Inc Inhibitors of thrombin
US5240913A (en) * 1989-08-18 1993-08-31 Biogen, Inc. Inhibitors of thrombin
ZA907743B (en) * 1989-10-03 1991-07-31 Merrell Dow Pharma Radiolabeled anticoagulant peptides
US5192747A (en) * 1989-10-03 1993-03-09 Merrell Dow Pharmaceuticals Inc. Anticoagulant peptides
AU641215B2 (en) * 1990-02-13 1993-09-16 Merrell Dow Pharmaceuticals Inc. Stabilized sulfonate, sulfate, phosphonate and phosphate derivatives of hirudin
US6060451A (en) * 1990-06-15 2000-05-09 The National Research Council Of Canada Thrombin inhibitors based on the amino acid sequence of hirudin
FR2667071A1 (fr) * 1990-09-26 1992-03-27 Adir Nouveaux derives de peptides et de pseudopeptides therapeutiquement actifs dans la cascade de coagulation sanguine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5242810A (en) * 1990-12-07 1993-09-07 Biogen, Inc. Bifunctional inhibitors of thrombin and platelet activation
US5477464A (en) * 1991-11-26 1995-12-19 Abb Flakt Ab Method for controlling the current pulse supply to an electrostatic precipitator
GB9303275D0 (en) * 1993-02-18 1993-04-07 Ciba Geigy Ag Pharmaceutical compositions
CN1113389A (zh) * 1993-08-04 1995-12-13 西巴-盖尔基股份公司 高分子量的脱硫水蛭素
US6057314A (en) * 1995-12-21 2000-05-02 Biochem Pharma Inc. Low molecular weight bicyclic thrombin inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3445532A1 (de) * 1984-12-13 1986-06-19 Plantorgan Werk Heinrich G.E. Christensen, KG, 2903 Bad Zwischenahn Hirudin-pa, desulfatohirudine-pa, verfahren zur herstellung und pharmazeutische mittel, die diese wirkstoffe enthalten

Also Published As

Publication number Publication date
IL86438A0 (en) 1988-11-15
ES2058176T3 (es) 1994-11-01
KR880013976A (ko) 1988-12-22
PT87536A (pt) 1989-05-31
ATE91490T1 (de) 1993-07-15
CA1340646C (en) 1999-07-13
EP0291982A2 (de) 1988-11-23
AU1634288A (en) 1988-11-24
FI882358A0 (fi) 1988-05-19
DE3882279T2 (de) 1993-10-28
EP0291982A3 (en) 1990-07-11
DE3882279D1 (de) 1993-08-19
JP2858249B2 (ja) 1999-02-17
FI89063B (fi) 1993-04-30
FI89063C (fi) 1993-08-10
EP0291982B1 (de) 1993-07-14
DK278488D0 (da) 1988-05-20
DK278488A (da) 1988-11-22
HU198513B (en) 1989-10-30
KR970010926B1 (ko) 1997-07-02
JPS63303996A (ja) 1988-12-12
NZ224678A (en) 1990-08-28
NO882238L (no) 1988-11-22
HUT46933A (en) 1988-12-28
CN88103015A (zh) 1988-12-21
AU613627B2 (en) 1991-08-08
NO882238D0 (no) 1988-05-20
PT87536B (pt) 1992-09-30
FI882358A (fi) 1988-11-22
ZA883443B (en) 1988-11-16

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Legal Events

Date Code Title Description
HC Change of name of proprietor(s)

Owner name: AVENTIS INC.

Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC.