IL85205A0 - Plasmid capable of high level expression in e. coli of soluble mature hil-1beta and derivatives with altered biological activity - Google Patents

Plasmid capable of high level expression in e. coli of soluble mature hil-1beta and derivatives with altered biological activity

Info

Publication number
IL85205A0
IL85205A0 IL85205A IL8520588A IL85205A0 IL 85205 A0 IL85205 A0 IL 85205A0 IL 85205 A IL85205 A IL 85205A IL 8520588 A IL8520588 A IL 8520588A IL 85205 A0 IL85205 A0 IL 85205A0
Authority
IL
Israel
Prior art keywords
1beta
coli
derivatives
high level
biological activity
Prior art date
Application number
IL85205A
Other languages
English (en)
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of IL85205A0 publication Critical patent/IL85205A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/72—Expression systems using regulatory sequences derived from the lac-operon

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
IL85205A 1987-01-27 1988-01-26 Plasmid capable of high level expression in e. coli of soluble mature hil-1beta and derivatives with altered biological activity IL85205A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US687087A 1987-01-27 1987-01-27
US07/132,185 US5047505A (en) 1987-01-27 1987-12-18 High level expression in E. coli of soluble mature HIL-1beta and derivatives with altered biological activity

Publications (1)

Publication Number Publication Date
IL85205A0 true IL85205A0 (en) 1988-07-31

Family

ID=26676180

Family Applications (1)

Application Number Title Priority Date Filing Date
IL85205A IL85205A0 (en) 1987-01-27 1988-01-26 Plasmid capable of high level expression in e. coli of soluble mature hil-1beta and derivatives with altered biological activity

Country Status (8)

Country Link
US (1) US5047505A (da)
EP (1) EP0276778A3 (da)
KR (1) KR900004428B1 (da)
AU (1) AU597142B2 (da)
CA (1) CA1305080C (da)
DK (1) DK35588A (da)
IL (1) IL85205A0 (da)
NZ (1) NZ223280A (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3587605T2 (de) * 1984-12-25 1994-03-17 Dainippon Pharmaceutical Co Interleukin-1 und dessen Derivat.
US5008374A (en) * 1986-03-14 1991-04-16 Otsuka Pharmaceutical Co., Ltd. IL-1α derivatives and drugs
US5290917A (en) * 1988-02-03 1994-03-01 Dainippon Pharmaceutical Co., Ltd. Modified polypeptides of IL-1α
US5120534A (en) * 1988-07-29 1992-06-09 Otsuka Pharmaceutical Co., Ltd. IL-1α derivatives and medicament for treating thrombocytopenia
WO1990010068A1 (en) * 1989-02-27 1990-09-07 New England Medical Center Hospitals, Inc. Il-1 biological activity inhibitors
WO1992013885A1 (en) * 1991-02-05 1992-08-20 University Of Maryland MODIFIED INTERLEUKIN-1$g(b)
ES2105972B1 (es) * 1995-08-03 1998-06-01 Cantabria Ind Farmaceutica Sa Un procedimiento para la obtencion de modificadores de las respuestas biologicas con actividad recuperadora de la funcion hematopoyetica a partir, igual e indistintamente, de dos cepas bacterianas fijadoras de n2 azotobacter chroococcum y azotobacter vinelandii.
US6626939B1 (en) * 1997-12-18 2003-09-30 Boston Scientific Scimed, Inc. Stent-graft with bioabsorbable structural support
EP2339351A1 (en) * 2003-09-08 2011-06-29 The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services Non-peptide agonists and antagonists of adrenomedullin and gastrin releasing peptide

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468464A (en) * 1974-11-04 1984-08-28 The Board Of Trustees Of The Leland Stanford Junior University Biologically functional molecular chimeras
DE3588241T2 (de) * 1984-05-18 2002-12-05 Massachusetts Institute Of Technology, Cambridge Menschliche IL-1 cDNS-Sequenzen die für biologisch aktive menschliche IL-1-Proteine kodieren
CA1340978C (en) * 1984-06-19 2000-05-02 Douglas P. Cerretti Purification, cloning and characterization of the gene for interleukin 1
DK172052B1 (da) * 1984-12-21 1997-09-29 Otsuka Pharma Co Ltd Antitumor-aktivt stof, fremgangsmåde til dets fremstilling, lægemiddel indeholdende stoffet, gen kodende for stoffet, vektor indeholdende genet samt rekombinant mikroorganisme transformet med en sådan vektor
AU595864B2 (en) * 1986-03-14 1990-04-12 Otsuka Pharmaceutical Co., Ltd. Il-1 alpha derivatives and drugs
JP2591615B2 (ja) * 1986-03-14 1997-03-19 大塚製薬株式会社 インターロイキン−１β誘導体及び医薬

Also Published As

Publication number Publication date
DK35588D0 (da) 1988-01-26
AU1076388A (en) 1988-07-28
NZ223280A (en) 1989-11-28
US5047505A (en) 1991-09-10
KR900004428B1 (ko) 1990-06-25
DK35588A (da) 1988-07-28
AU597142B2 (en) 1990-05-24
EP0276778A3 (en) 1990-01-10
KR880009127A (ko) 1988-09-14
EP0276778A2 (en) 1988-08-03
CA1305080C (en) 1992-07-14

Similar Documents

Publication Publication Date Title
IL88182A0 (en) Derivatives of 1-desoxynojirimicyin and 1-desoxymannonojirimycin,their preparation and their use in medicaments
NZ223227A (en) Phosphinothricin-resistance gene active in plants and its use
IL86671A0 (en) Hyaluronic acid derivatives and their preparation
EP0292437A3 (en) Piperidylaminotriazine derivatives and their use as stabilizers
IL75979A0 (en) Propargyloxyacetonitrile derivatives,their preparation and their use in agriculture
IL91301A0 (en) Annelated tetrahydropyridine acetic acid derivatives,the preparation and use thereof
EG19184A (en) 4-Nitro-n- phenylpyrazole derivatives and their use as pesticide
IL87089A0 (en) N-aminobutyl-n-phenylarylamide derivatives,their preparation and their application in therapy
NZ226875A (en) E coli having 20% of the acetate forming ability of the wild type and its use in fermentation
IL85205A0 (en) Plasmid capable of high level expression in e. coli of soluble mature hil-1beta and derivatives with altered biological activity
IL86649A0 (en) 2-guanidino-thiazole derivatives,their preparation and use as intermediates
NZ223812A (en) Morpholine derivatives and their use in agriculture and medicine
EP0310126A3 (en) Derivatives of pyrocatechol-carboxylic acid, their preparation and use as active ingredients in medicines
IL88608A0 (en) 3-hydroxy-2-(4-methoxyphenyl)-5-(2-methylaminoethyl)-2-3,dihydro-5h-1,5-benzothiazepin-4-one derivatives,their preparation and their application in therapy
ZA88554B (en) High level expression in e.coli of soluble mature hil-1beta and derivatives with altered biological activity
ZA888701B (en) Expression of hiv proteins in e.coli and s. cerevisiae
GB2157684B (en) Triazolopyrimidines their preparation and use in medicine
AR243886A1 (es) Proceso para la preparacion de derivados de 2-carboxamido-tiofeno.
EG18799A (en) Phenylthioureas, phenylisothioureas and phenylcarbodumides their preparation and use in the control of pests
AU4124189A (en) Novel pyridyl aminoethanols with animal growth promotion activity and a high degree of safety
EP0317649A4 (en) Novel plasmid, microbial cells, process for preparing polypeptide with oncostatic activity, and secreted polypeptide with oncostatic activity
IL86187A0 (en) Pyrrolophenylalkanolamines and their derivatives,their preparation and their use as yield promoters in animals
GB2208863B (en) Production of 2-methyl-5-isopropyl-hexa-2,5-dien-1-al and of 2-methyl-5-isopropyl-hexa-2,4-dien-1-al in microorganisms
Willis Moral Imagination in Kaguru Modes of Thought
Bailey Effect of selection for body weight on growth rate, growth efficiency and carcass composition in mice