IL82579A0 - Immunoglobulin conjugates - Google Patents
Immunoglobulin conjugatesInfo
- Publication number
- IL82579A0 IL82579A0 IL82579A IL8257987A IL82579A0 IL 82579 A0 IL82579 A0 IL 82579A0 IL 82579 A IL82579 A IL 82579A IL 8257987 A IL8257987 A IL 8257987A IL 82579 A0 IL82579 A0 IL 82579A0
- Authority
- IL
- Israel
- Prior art keywords
- immunoglobulin conjugates
- conjugates
- immunoglobulin
- Prior art date
Links
- 108060003951 Immunoglobulin Proteins 0.000 title 1
- 102000018358 immunoglobulin Human genes 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6805—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a vinca alkaloid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/20—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/18—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86718386A | 1986-05-27 | 1986-05-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL82579A0 true IL82579A0 (en) | 1987-11-30 |
Family
ID=25349292
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL82579A IL82579A0 (en) | 1986-05-27 | 1987-05-19 | Immunoglobulin conjugates |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0247792A3 (de) |
| JP (1) | JPS62287000A (de) |
| KR (1) | KR900006908B1 (de) |
| CN (1) | CN87104430A (de) |
| AU (1) | AU600727B2 (de) |
| CA (1) | CA1288896C (de) |
| DK (1) | DK260687A (de) |
| HU (1) | HUT44033A (de) |
| IL (1) | IL82579A0 (de) |
| NZ (1) | NZ220441A (de) |
| PT (1) | PT84932B (de) |
| SU (1) | SU1561825A3 (de) |
| ZA (1) | ZA873600B (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8728856D0 (en) * | 1987-12-10 | 1988-01-27 | Bradwell A R | Tumour-locating agents & method of locating tumours |
| IL89043A0 (en) * | 1988-01-27 | 1989-08-15 | Lilly Co Eli | Antibody conjugates |
| US5006652A (en) * | 1988-08-08 | 1991-04-09 | Eli Lilly And Company | Intermediates for antibody-vinca drug conjugates |
| US5010176A (en) * | 1988-11-10 | 1991-04-23 | Eli Lilly And Company | Antibody-drug conjugates |
| AU5252090A (en) * | 1989-04-04 | 1990-10-11 | Eli Lilly And Company | Improvements in and relating to pharmaceutical formulations |
| AU648313B2 (en) * | 1990-04-25 | 1994-04-21 | Pharmacia & Upjohn Company | Novel CC-1065 analogs |
| JP2000506494A (ja) * | 1995-10-18 | 2000-05-30 | メルク エンド カンパニー インコーポレーテッド | 良性前立腺過形成の治療に有用な複合体 |
| EP1389209B1 (de) | 2001-04-24 | 2009-04-08 | Purdue Research Foundation | Folat-mimetika und deren folatrezeptorbindende konjugate |
| US7910594B2 (en) | 2002-05-15 | 2011-03-22 | Endocyte, Inc. | Vitamin-mitomycin conjugates |
| AR042942A1 (es) | 2003-01-27 | 2005-07-06 | Endocyte Inc | Conjugados de administracion de drogas de union de receptores de vitaminas |
| EP1789391B1 (de) | 2004-07-23 | 2017-06-28 | Endocyte, Inc. | Zweiwertige linker und konjugate davon |
| CN101175757B (zh) | 2005-03-16 | 2012-11-14 | 恩多塞特公司 | 蝶酸及其缀合物的合成和纯化 |
| WO2007022493A2 (en) | 2005-08-19 | 2007-02-22 | Endocyte, Inc. | Ligand conjugates of vinca alkaloids, analogs, and derivatives |
| CN103893778A (zh) | 2005-08-19 | 2014-07-02 | 恩多塞特公司 | 多药物配体缀合物 |
| WO2008101231A2 (en) | 2007-02-16 | 2008-08-21 | Endocyte, Inc. | Methods and compositions for treating and diagnosing kidney disease |
| JP5829793B2 (ja) | 2007-03-14 | 2015-12-09 | エンドサイト・インコーポレイテッドＥｎｄｏｃｙｔｅ， Ｉｎｃ． | 結合性リガンドが結合したツブリシンの薬剤送達結合体 |
| WO2009002993A1 (en) | 2007-06-25 | 2008-12-31 | Endocyte, Inc. | Conjugates containing hydrophilic spacer linkers |
| US9877965B2 (en) | 2007-06-25 | 2018-01-30 | Endocyte, Inc. | Vitamin receptor drug delivery conjugates for treating inflammation |
| WO2013126797A1 (en) | 2012-02-24 | 2013-08-29 | Purdue Research Foundation | Cholecystokinin b receptor targeting for imaging and therapy |
| US20140080175A1 (en) | 2012-03-29 | 2014-03-20 | Endocyte, Inc. | Processes for preparing tubulysin derivatives and conjugates thereof |
| EP2908818A4 (de) | 2012-10-16 | 2016-07-13 | Endocyte Inc | Wirkstofffreisetzungskonjugate mit unnatürlichen aminosäuren und verfahren zur verwendung |
| CN108948128B (zh) * | 2018-07-02 | 2021-10-01 | 中国科学技术大学 | 一种基于缺电子苯甲醛的无催化剂腙连接多肽或蛋白质化学修饰方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI820020A7 (fi) * | 1981-01-12 | 1982-07-13 | Lilly Industries Ltd | Immunoglobuliinikonjugaatteja. |
| EP0121388B1 (de) * | 1983-03-30 | 1990-06-13 | Lilly Industries Limited | Immunoglobulinkonjugate |
| US4675400A (en) * | 1985-06-17 | 1987-06-23 | Eli Lilly And Company | Bifunctional derivatives of 4-desacetyl indole-dihydroindole alkaloids |
| ATE89567T1 (de) * | 1985-11-12 | 1993-06-15 | Wallone Region | Konjugate von vinblastin und seine derivate, verfahren zur herstellung derselben und diese konjugate enthaltende pharmazeutische zusammensetzungen. |
-
1987
- 1987-05-19 IL IL82579A patent/IL82579A0/xx unknown
- 1987-05-19 ZA ZA873600A patent/ZA873600B/xx unknown
- 1987-05-20 CA CA000537474A patent/CA1288896C/en not_active Expired - Lifetime
- 1987-05-21 EP EP87304516A patent/EP0247792A3/de not_active Withdrawn
- 1987-05-22 SU SU874202656A patent/SU1561825A3/ru active
- 1987-05-22 PT PT84932A patent/PT84932B/pt not_active IP Right Cessation
- 1987-05-22 DK DK260687A patent/DK260687A/da not_active Application Discontinuation
- 1987-05-25 AU AU73349/87A patent/AU600727B2/en not_active Ceased
- 1987-05-25 KR KR1019870005156A patent/KR900006908B1/ko not_active Expired
- 1987-05-26 CN CN198787104430A patent/CN87104430A/zh active Pending
- 1987-05-26 JP JP62129573A patent/JPS62287000A/ja active Pending
- 1987-05-26 NZ NZ220441A patent/NZ220441A/xx unknown
- 1987-05-26 HU HU872417A patent/HUT44033A/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN87104430A (zh) | 1988-05-11 |
| DK260687D0 (da) | 1987-05-22 |
| JPS62287000A (ja) | 1987-12-12 |
| KR870011132A (ko) | 1987-12-21 |
| EP0247792A2 (de) | 1987-12-02 |
| AU600727B2 (en) | 1990-08-23 |
| DK260687A (da) | 1987-11-28 |
| PT84932A (en) | 1987-06-01 |
| SU1561825A3 (ru) | 1990-04-30 |
| AU7334987A (en) | 1987-12-03 |
| PT84932B (pt) | 1990-02-08 |
| HUT44033A (en) | 1988-01-28 |
| ZA873600B (en) | 1988-12-28 |
| CA1288896C (en) | 1991-09-10 |
| NZ220441A (en) | 1989-09-27 |
| KR900006908B1 (ko) | 1990-09-24 |
| EP0247792A3 (de) | 1989-07-12 |
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