DK260687A - Immunoglobulin-konjugater og fremgangsmaade til fremstilling deraf - Google Patents
Immunoglobulin-konjugater og fremgangsmaade til fremstilling derafInfo
- Publication number
- DK260687A DK260687A DK260687A DK260687A DK260687A DK 260687 A DK260687 A DK 260687A DK 260687 A DK260687 A DK 260687A DK 260687 A DK260687 A DK 260687A DK 260687 A DK260687 A DK 260687A
- Authority
- DK
- Denmark
- Prior art keywords
- procedures
- preparing
- immunoglobulin conjugates
- conjugates
- immunoglobulin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/20—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6805—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a vinca alkaloid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/18—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86718386A | 1986-05-27 | 1986-05-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK260687D0 DK260687D0 (da) | 1987-05-22 |
| DK260687A true DK260687A (da) | 1987-11-28 |
Family
ID=25349292
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK260687A DK260687A (da) | 1986-05-27 | 1987-05-22 | Immunoglobulin-konjugater og fremgangsmaade til fremstilling deraf |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0247792A3 (da) |
| JP (1) | JPS62287000A (da) |
| KR (1) | KR900006908B1 (da) |
| CN (1) | CN87104430A (da) |
| AU (1) | AU600727B2 (da) |
| CA (1) | CA1288896C (da) |
| DK (1) | DK260687A (da) |
| HU (1) | HUT44033A (da) |
| IL (1) | IL82579A0 (da) |
| NZ (1) | NZ220441A (da) |
| PT (1) | PT84932B (da) |
| SU (1) | SU1561825A3 (da) |
| ZA (1) | ZA873600B (da) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8728856D0 (en) * | 1987-12-10 | 1988-01-27 | Bradwell A R | Tumour-locating agents & method of locating tumours |
| PT89504A (pt) * | 1988-01-27 | 1989-10-04 | Lilly Co Eli | Processo para a preparacao de conjugados de anticorpos com hidrazidas de vinca |
| US5006652A (en) * | 1988-08-08 | 1991-04-09 | Eli Lilly And Company | Intermediates for antibody-vinca drug conjugates |
| US5010176A (en) * | 1988-11-10 | 1991-04-23 | Eli Lilly And Company | Antibody-drug conjugates |
| CA2013600A1 (en) * | 1989-04-04 | 1990-10-04 | Michael J. Pikal | Pharmaceutical formulations |
| EP0527189A1 (en) * | 1990-04-25 | 1993-02-17 | PHARMACIA & UPJOHN COMPANY | Novel cc-1065 analogs |
| EP0855910A4 (en) * | 1995-10-18 | 2000-07-05 | Merck & Co Inc | CONJUGATES USEFUL FOR TREATING BENIN PROSTATIC ADENOMA |
| EP1389209B1 (en) | 2001-04-24 | 2009-04-08 | Purdue Research Foundation | Folate mimetics and folate-receptor binding conjugates thereof |
| US7910594B2 (en) | 2002-05-15 | 2011-03-22 | Endocyte, Inc. | Vitamin-mitomycin conjugates |
| CA2512867C (en) | 2003-01-27 | 2014-08-26 | Endocyte, Inc. | Vitamin receptor binding drug delivery conjugates |
| WO2006012527A1 (en) | 2004-07-23 | 2006-02-02 | Endocyte, Inc. | Bivalent linkers and conjugates thereof |
| CN101175757B (zh) | 2005-03-16 | 2012-11-14 | 恩多塞特公司 | 蝶酸及其缀合物的合成和纯化 |
| US20080280937A1 (en) | 2005-08-19 | 2008-11-13 | Christopher Paul Leamon | Ligand Conjugates of Vinca Alkaloids, Analogs, and Derivatives |
| CA2617660C (en) | 2005-08-19 | 2014-03-25 | Endocyte, Inc. | Multi-drug ligand conjugates |
| WO2008101231A2 (en) | 2007-02-16 | 2008-08-21 | Endocyte, Inc. | Methods and compositions for treating and diagnosing kidney disease |
| EP2139523B1 (en) | 2007-03-14 | 2014-10-22 | Endocyte, Inc. | Conjugates of folate and tubulysin for targeted drug delivery |
| AU2008268432B2 (en) | 2007-06-25 | 2015-01-15 | Endocyte, Inc. | Conjugates containing hydrophilic spacer linkers |
| US9877965B2 (en) | 2007-06-25 | 2018-01-30 | Endocyte, Inc. | Vitamin receptor drug delivery conjugates for treating inflammation |
| US10080805B2 (en) | 2012-02-24 | 2018-09-25 | Purdue Research Foundation | Cholecystokinin B receptor targeting for imaging and therapy |
| US20140080175A1 (en) | 2012-03-29 | 2014-03-20 | Endocyte, Inc. | Processes for preparing tubulysin derivatives and conjugates thereof |
| IN2015DN04147A (da) | 2012-10-16 | 2015-10-16 | Endocyte Inc | |
| CN108948128B (zh) * | 2018-07-02 | 2021-10-01 | 中国科学技术大学 | 一种基于缺电子苯甲醛的无催化剂腙连接多肽或蛋白质化学修饰方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI820020L (fi) * | 1981-01-12 | 1982-07-13 | Lilly Industries Ltd | Immunoglobulinkonjugater |
| GB2137210B (en) * | 1983-03-30 | 1986-11-19 | Lilly Industries Ltd | Immunoglobulin conjugates |
| US4675400A (en) * | 1985-06-17 | 1987-06-23 | Eli Lilly And Company | Bifunctional derivatives of 4-desacetyl indole-dihydroindole alkaloids |
| ATE89567T1 (de) * | 1985-11-12 | 1993-06-15 | Wallone Region | Konjugate von vinblastin und seine derivate, verfahren zur herstellung derselben und diese konjugate enthaltende pharmazeutische zusammensetzungen. |
-
1987
- 1987-05-19 IL IL82579A patent/IL82579A0/xx unknown
- 1987-05-19 ZA ZA873600A patent/ZA873600B/xx unknown
- 1987-05-20 CA CA000537474A patent/CA1288896C/en not_active Expired - Lifetime
- 1987-05-21 EP EP87304516A patent/EP0247792A3/en not_active Withdrawn
- 1987-05-22 SU SU874202656A patent/SU1561825A3/ru active
- 1987-05-22 DK DK260687A patent/DK260687A/da not_active Application Discontinuation
- 1987-05-22 PT PT84932A patent/PT84932B/pt not_active IP Right Cessation
- 1987-05-25 KR KR1019870005156A patent/KR900006908B1/ko not_active IP Right Cessation
- 1987-05-25 AU AU73349/87A patent/AU600727B2/en not_active Ceased
- 1987-05-26 CN CN198787104430A patent/CN87104430A/zh active Pending
- 1987-05-26 JP JP62129573A patent/JPS62287000A/ja active Pending
- 1987-05-26 NZ NZ220441A patent/NZ220441A/xx unknown
- 1987-05-26 HU HU872417A patent/HUT44033A/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0247792A3 (en) | 1989-07-12 |
| EP0247792A2 (en) | 1987-12-02 |
| KR870011132A (ko) | 1987-12-21 |
| PT84932A (en) | 1987-06-01 |
| ZA873600B (en) | 1988-12-28 |
| CA1288896C (en) | 1991-09-10 |
| JPS62287000A (ja) | 1987-12-12 |
| AU7334987A (en) | 1987-12-03 |
| IL82579A0 (en) | 1987-11-30 |
| HUT44033A (en) | 1988-01-28 |
| SU1561825A3 (ru) | 1990-04-30 |
| AU600727B2 (en) | 1990-08-23 |
| CN87104430A (zh) | 1988-05-11 |
| PT84932B (pt) | 1990-02-08 |
| KR900006908B1 (ko) | 1990-09-24 |
| DK260687D0 (da) | 1987-05-22 |
| NZ220441A (en) | 1989-09-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |