IL82215A - Peptide-resin and protected peptide compounds and their preparation - Google Patents

Peptide-resin and protected peptide compounds and their preparation

Info

Publication number
IL82215A
IL82215A IL82215A IL8221582A IL82215A IL 82215 A IL82215 A IL 82215A IL 82215 A IL82215 A IL 82215A IL 8221582 A IL8221582 A IL 8221582A IL 82215 A IL82215 A IL 82215A
Authority
IL
Israel
Prior art keywords
peptide
resin
preparation
protected
compounds
Prior art date
Application number
IL82215A
Other languages
English (en)
Original Assignee
Beckman Instruments Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/335,000 external-priority patent/US4410513A/en
Priority claimed from US06/334,488 external-priority patent/US4410512A/en
Priority claimed from US06/335,011 external-priority patent/US4411890A/en
Application filed by Beckman Instruments Inc filed Critical Beckman Instruments Inc
Publication of IL82215A publication Critical patent/IL82215A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/60Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Obesity (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IL82215A 1981-12-28 1982-12-28 Peptide-resin and protected peptide compounds and their preparation IL82215A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/335,000 US4410513A (en) 1981-12-28 1981-12-28 Synthetic peptides having pituitary growth hormone releasing activity
US06/334,488 US4410512A (en) 1981-12-28 1981-12-28 Combinations having synergistic pituitary growth hormone releasing activity
US06/335,011 US4411890A (en) 1981-04-14 1981-12-28 Synthetic peptides having pituitary growth hormone releasing activity
IL67577A IL67577A (en) 1981-12-28 1982-12-28 Penta-and hexapeptides having growth hormone releasing activity,their preparation and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
IL82215A true IL82215A (en) 1988-07-31

Family

ID=27406978

Family Applications (2)

Application Number Title Priority Date Filing Date
IL67577A IL67577A (en) 1981-12-28 1982-12-28 Penta-and hexapeptides having growth hormone releasing activity,their preparation and pharmaceutical compositions containing them
IL82215A IL82215A (en) 1981-12-28 1982-12-28 Peptide-resin and protected peptide compounds and their preparation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL67577A IL67577A (en) 1981-12-28 1982-12-28 Penta-and hexapeptides having growth hormone releasing activity,their preparation and pharmaceutical compositions containing them

Country Status (14)

Country Link
EP (1) EP0083864B1 (ko)
JP (1) JPS58501861A (ko)
KR (2) KR890002760B1 (ko)
AU (1) AU549053B2 (ko)
BR (1) BR8208035A (ko)
CA (2) CA1242435A (ko)
DE (1) DE3276319D1 (ko)
DK (2) DK390883D0 (ko)
DO (1) DOP1982004152A (ko)
FI (1) FI77251C (ko)
IE (1) IE54515B1 (ko)
IL (2) IL67577A (ko)
PT (1) PT76041B (ko)
WO (1) WO1983002272A1 (ko)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4839344A (en) * 1987-06-12 1989-06-13 Eastman Kodak Company Polypeptide compounds having growth hormone releasing activity
AU618029B2 (en) * 1987-11-02 1991-12-12 Imperial Chemical Industries Plc Polypeptide compounds
EP0400051B1 (en) * 1988-01-28 1995-05-10 Polygen Holding Corporation Polypeptide compounds having growth hormone releasing activity
DE68919213T2 (de) * 1988-01-28 1995-05-11 Polygen Holding Corp Polypeptidverbindungen mit wachstumshormonfreisetzender aktivität.
AU633003B2 (en) * 1988-05-11 1993-01-21 Polygen Holding Corporation Polypeptide compounds having growth hormone releasing activity
GB8813356D0 (en) * 1988-06-06 1988-07-13 Ici Plc Polypeptide compounds
EP0448513A3 (en) * 1990-03-21 1991-12-27 Japat Ltd Process for production of peptidylglycine alpha-hydroxylating monooxygenase and use thereof
US5872100A (en) * 1990-05-11 1999-02-16 Deghenghi; Romano Peptides containing D-2-Alkyl-Tryptophan
IT1240643B (it) * 1990-05-11 1993-12-17 Mediolanum Farmaceutici Spa Peptidi biologicamente attivi contenenti in catena 2-alchiltriptofano
US5668254A (en) * 1990-05-11 1997-09-16 Romano Deghenghi D-2-alkyl-tryptophan and peptides containing same
US5492894A (en) * 1991-03-21 1996-02-20 The Procter & Gamble Company Compositions for treating wrinkles comprising a peptide
US5663146A (en) * 1991-08-22 1997-09-02 Administrators Of The Tulane Educational Fund Polypeptide analogues having growth hormone releasing activity
SK281963B6 (sk) * 1993-12-23 2001-09-11 Novo Nordisk A/S Zlúčeniny ovplyvňujúce uvoľňovanie rastového hormónu, farmaceutické prostriedky s ich obsahom a ich použitie
CA2201122A1 (en) * 1994-09-27 1996-04-04 Romano Deghenghi Polypeptide compounds containing d-2-alkyltryptophan capable of promoting the release of growth hormone
JP4116097B2 (ja) 1997-06-20 2008-07-09 ノボ ノルディスク アクティーゼルスカブ 成長ホルモン放出特性をもつ化合物
WO1999036431A1 (en) 1998-01-16 1999-07-22 Novo Nordisk A/S Compounds with growth hormone releasing properties
US6919315B1 (en) 1998-06-30 2005-07-19 Novo Nordisk A/S Compounds with growth hormone releasing properties
WO2000009537A2 (en) * 1998-08-14 2000-02-24 Administrators Of The Tulane Educational Fund Compounds having growth hormone releasing activity
US9119832B2 (en) 2014-02-05 2015-09-01 The Regents Of The University Of California Methods of treating mild brain injury
US20170121385A1 (en) 2015-10-28 2017-05-04 Oxeia Biopharmaceuticals, Inc. Methods of treating neurodegenerative conditions
CN106216464B (zh) * 2016-09-27 2017-12-12 天津职业技术师范大学 中空薄壁管件旋拧设备及其运行方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2871225A (en) * 1954-06-03 1959-01-27 Rohm & Haas Method for preparing polypeptides
US3093627A (en) * 1958-07-03 1963-06-11 Ciba Geigy Corp Polypeptides and process for their manufacture
US3664925A (en) * 1970-02-20 1972-05-23 Martin Sonenberg Clinically active bovine growth hormone fraction
DE2158123A1 (de) * 1970-12-02 1972-06-08 Ciba-Geigy Ag, Basel (Schweiz) Neue pharmazeutische Präparate
US3862925A (en) * 1973-07-05 1975-01-28 American Home Prod Preparation of somatotropin release inhibiting factor and intermediates therefor
JPS5726506B2 (ko) * 1974-03-08 1982-06-04
CH644352A5 (en) * 1976-01-26 1984-07-31 Wellcome Found Process for the preparation of peptides
EP0000559B1 (en) * 1977-07-22 1983-10-05 The Wellcome Foundation Limited Pentapeptide-n-alkylamides and their acid addition salts, methods for preparation of these compounds and pharmaceutical formulations containing them
US4228155A (en) * 1979-03-30 1980-10-14 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4228158A (en) * 1979-03-30 1980-10-14 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4228156A (en) * 1979-03-30 1980-10-14 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4223019A (en) * 1979-03-30 1980-09-16 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4224316A (en) * 1979-03-30 1980-09-23 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
CA1175810A (en) * 1979-03-30 1984-10-09 Frank A. Momany Synthetic peptides having pituitary growth hormone releasing activity
US4223020A (en) * 1979-03-30 1980-09-16 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4223021A (en) * 1979-03-30 1980-09-16 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4226857A (en) * 1979-03-30 1980-10-07 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4228157A (en) * 1979-03-30 1980-10-14 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4251439A (en) * 1979-12-17 1981-02-17 Eli Lilly And Company Pharmacologically active peptides

Also Published As

Publication number Publication date
JPS58501861A (ja) 1983-11-04
FI833057A0 (fi) 1983-08-26
DK390883A (da) 1983-08-26
FI77251C (fi) 1989-02-10
EP0083864A3 (en) 1983-09-14
CA1242435A (en) 1988-09-27
IE823072L (en) 1983-06-28
DE3276319D1 (en) 1987-06-19
EP0083864A2 (en) 1983-07-20
PT76041A (en) 1983-01-01
DK114192D0 (da) 1992-09-16
DK114192A (da) 1992-09-16
WO1983002272A1 (en) 1983-07-07
KR890002760B1 (ko) 1989-07-27
KR900002681B1 (ko) 1990-04-23
IE54515B1 (en) 1989-11-08
CA1317069C (en) 1993-04-27
IL67577A (en) 1988-07-31
FI833057A (fi) 1983-08-26
BR8208035A (pt) 1983-11-22
DOP1982004152A (es) 1988-09-01
FI77251B (fi) 1988-10-31
PT76041B (en) 1985-07-26
KR840002772A (ko) 1984-07-16
EP0083864B1 (en) 1987-05-13
DK390883D0 (da) 1983-08-26
AU549053B2 (en) 1986-01-09

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Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
EXP Patent expired