IL81394A - 4-aryl-pyrrolidin-2-one derivatives,process for their preparation and pharmaceutical compositions containing them - Google Patents

4-aryl-pyrrolidin-2-one derivatives,process for their preparation and pharmaceutical compositions containing them

Info

Publication number
IL81394A
IL81394A IL81394A IL8139487A IL81394A IL 81394 A IL81394 A IL 81394A IL 81394 A IL81394 A IL 81394A IL 8139487 A IL8139487 A IL 8139487A IL 81394 A IL81394 A IL 81394A
Authority
IL
Israel
Prior art keywords
radical
formula
image
phenyl
represents hydrogen
Prior art date
Application number
IL81394A
Other languages
English (en)
Other versions
IL81394A0 (en
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL81394A0 publication Critical patent/IL81394A0/xx
Publication of IL81394A publication Critical patent/IL81394A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL81394A 1986-01-30 1987-01-27 4-aryl-pyrrolidin-2-one derivatives,process for their preparation and pharmaceutical compositions containing them IL81394A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH34686 1986-01-30

Publications (2)

Publication Number Publication Date
IL81394A0 IL81394A0 (en) 1987-08-31
IL81394A true IL81394A (en) 1991-08-16

Family

ID=4184917

Family Applications (1)

Application Number Title Priority Date Filing Date
IL81394A IL81394A (en) 1986-01-30 1987-01-27 4-aryl-pyrrolidin-2-one derivatives,process for their preparation and pharmaceutical compositions containing them

Country Status (21)

Country Link
US (1) US4945092A (xx)
EP (1) EP0236263B1 (xx)
JP (1) JPS62185068A (xx)
KR (1) KR870007159A (xx)
AT (1) ATE84033T1 (xx)
AU (1) AU599951B2 (xx)
CA (1) CA1312081C (xx)
DD (1) DD260066A5 (xx)
DE (1) DE3783247D1 (xx)
DK (1) DK47187A (xx)
ES (1) ES2053578T3 (xx)
FI (1) FI870329A (xx)
GR (1) GR3007411T3 (xx)
HU (1) HU202862B (xx)
IE (1) IE61100B1 (xx)
IL (1) IL81394A (xx)
NO (1) NO870374L (xx)
NZ (1) NZ219101A (xx)
PH (1) PH23078A (xx)
PT (1) PT84204B (xx)
ZA (1) ZA87650B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
EP1354882A1 (en) * 2000-12-27 2003-10-22 Kyowa Hakko Kogyo Co., Ltd. Dipeptidyl peptidase iv inhibitor
EP4101561A1 (de) 2021-06-08 2022-12-14 Meusburger Georg GmbH & Co. KG Zentriereinrichtung für ein formwerkzeug mit gleichzeitig tragenden wälzkörpereinheiten

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1039113A (en) * 1964-08-06 1966-08-17 Ucb Sa New n-substituted lactams
US4144246A (en) * 1976-11-15 1979-03-13 Parke, Davis & Company Pyrrolidineacetic acid esters
BE864269A (fr) * 1977-03-03 1978-06-16 Parke Davis & Co Nouveaux n-(aminoalkyl substitue)-2-oxo-1-pyrrolidine-acetamides et procedes pour les produire
DE2757680A1 (de) * 1977-12-23 1979-06-28 Troponwerke Gmbh & Co Kg Neue 2-oxo-1-pyrrolidinessigsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
EP0089900B1 (en) * 1982-03-24 1985-12-27 Prodes S.A. New n-((2-oxo-1-pyrrolidinyl)acetyl)piperazines, the methods of producing such new compounds and their salts as well as pharmaceutical preparations for therapeutic use containing these compounds or salts

Also Published As

Publication number Publication date
DE3783247D1 (de) 1993-02-11
FI870329A0 (fi) 1987-01-26
NO870374D0 (no) 1987-01-29
FI870329A (fi) 1987-07-31
IE870230L (en) 1987-07-30
PH23078A (en) 1989-04-10
NO870374L (no) 1987-07-31
EP0236263A3 (en) 1989-04-19
PT84204A (en) 1987-02-01
IE61100B1 (en) 1994-10-05
DK47187A (da) 1987-07-31
DK47187D0 (da) 1987-01-29
JPH0558631B2 (xx) 1993-08-27
ZA87650B (en) 1987-09-30
HUT43058A (en) 1987-09-28
AU599951B2 (en) 1990-08-02
EP0236263B1 (de) 1992-12-30
ES2053578T3 (es) 1994-08-01
CA1312081C (en) 1992-12-29
IL81394A0 (en) 1987-08-31
ATE84033T1 (de) 1993-01-15
EP0236263A2 (de) 1987-09-09
DD260066A5 (de) 1988-09-14
US4945092A (en) 1990-07-31
GR3007411T3 (xx) 1993-07-30
KR870007159A (ko) 1987-08-17
NZ219101A (en) 1990-03-27
JPS62185068A (ja) 1987-08-13
HU202862B (en) 1991-04-29
PT84204B (pt) 1989-09-14
AU6809787A (en) 1987-08-06

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Legal Events

Date Code Title Description
RH Patent void