IL76490A - Preparation of 4-hydroxycoumarin derivatives - Google Patents
Preparation of 4-hydroxycoumarin derivativesInfo
- Publication number
- IL76490A IL76490A IL76490A IL7649085A IL76490A IL 76490 A IL76490 A IL 76490A IL 76490 A IL76490 A IL 76490A IL 7649085 A IL7649085 A IL 7649085A IL 76490 A IL76490 A IL 76490A
- Authority
- IL
- Israel
- Prior art keywords
- chem
- group
- range
- atom
- alkyl
- Prior art date
Links
- VXIXUWQIVKSKSA-UHFFFAOYSA-N 4-hydroxycoumarin Chemical class C1=CC=CC2=C1OC(=O)C=C2O VXIXUWQIVKSKSA-UHFFFAOYSA-N 0.000 title abstract 4
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical group COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 238000009835 boiling Methods 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 235000019253 formic acid Nutrition 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 2
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 1
- KEIFWROAQVVDBN-UHFFFAOYSA-N 1,2-dihydronaphthalene Chemical compound C1=CC=C2C=CCCC2=C1 KEIFWROAQVVDBN-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 230000002429 anti-coagulating effect Effects 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 150000008282 halocarbons Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 239000003128 rodenticide Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
- C07D311/56—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 without hydrogen atoms in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Electric Propulsion And Braking For Vehicles (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Vibration Dampers (AREA)
- Control Of Electric Motors In General (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Saccharide Compounds (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848424317A GB8424317D0 (en) | 1984-09-26 | 1984-09-26 | 4-hydroxycourmarin derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL76490A0 IL76490A0 (en) | 1986-01-31 |
| IL76490A true IL76490A (en) | 1989-07-31 |
Family
ID=10567286
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL76490A IL76490A (en) | 1984-09-26 | 1985-09-24 | Preparation of 4-hydroxycoumarin derivatives |
Country Status (28)
| Country | Link |
|---|---|
| EP (1) | EP0177080B1 (ja) |
| JP (2) | JPH0794449B2 (ja) |
| KR (1) | KR930009794B1 (ja) |
| AT (1) | ATE38669T1 (ja) |
| AU (1) | AU583533B2 (ja) |
| BR (1) | BR8504673A (ja) |
| CA (1) | CA1263396A (ja) |
| DE (1) | DE3566258D1 (ja) |
| DK (1) | DK162993C (ja) |
| EG (1) | EG17061A (ja) |
| ES (1) | ES8604920A1 (ja) |
| FI (1) | FI86718C (ja) |
| GB (1) | GB8424317D0 (ja) |
| GR (1) | GR852319B (ja) |
| HU (1) | HU196982B (ja) |
| IE (1) | IE58616B1 (ja) |
| IL (1) | IL76490A (ja) |
| IN (1) | IN166513B (ja) |
| MA (1) | MA20532A1 (ja) |
| NO (1) | NO169772C (ja) |
| NZ (1) | NZ213591A (ja) |
| OA (1) | OA08104A (ja) |
| PH (1) | PH22719A (ja) |
| PT (1) | PT81183B (ja) |
| SU (1) | SU1358785A3 (ja) |
| ZA (1) | ZA857326B (ja) |
| ZM (1) | ZM6985A1 (ja) |
| ZW (1) | ZW16985A1 (ja) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8424317D0 (en) * | 1984-09-26 | 1984-10-31 | Shell Int Research | 4-hydroxycourmarin derivatives |
| GB9324517D0 (en) * | 1993-11-30 | 1994-01-19 | Octel Chem Ltd | Process for the preparation of substituted 4-hydroxycoumarins |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1458670A (en) * | 1973-05-23 | 1976-12-15 | Ward Blenkinsop & Co Ltd | Anti coagulant 3-tetrahydronaphthyl-4-hydroxy-coumarin deri vatives |
| EP0098629B1 (en) * | 1982-06-14 | 1987-08-26 | Shell Internationale Researchmaatschappij B.V. | Anti-coagulants of the 4-hydroxycoumarin type, the preparation thereof, and rodenticidal compositions (baits) comprising such anti-coagulants |
| GB8424317D0 (en) * | 1984-09-26 | 1984-10-31 | Shell Int Research | 4-hydroxycourmarin derivatives |
-
1984
- 1984-09-26 GB GB848424317A patent/GB8424317D0/en active Pending
-
1985
- 1985-09-06 CA CA000490120A patent/CA1263396A/en not_active Expired
- 1985-09-10 AT AT85201436T patent/ATE38669T1/de not_active IP Right Cessation
- 1985-09-10 DE DE8585201436T patent/DE3566258D1/de not_active Expired
- 1985-09-10 EP EP85201436A patent/EP0177080B1/en not_active Expired
- 1985-09-20 PH PH32818A patent/PH22719A/en unknown
- 1985-09-20 ZM ZM69/85A patent/ZM6985A1/xx unknown
- 1985-09-23 GR GR852319A patent/GR852319B/el unknown
- 1985-09-24 HU HU853592A patent/HU196982B/hu unknown
- 1985-09-24 JP JP60209026A patent/JPH0794449B2/ja not_active Expired - Lifetime
- 1985-09-24 EG EG606/85A patent/EG17061A/xx active
- 1985-09-24 NZ NZ213591A patent/NZ213591A/en unknown
- 1985-09-24 IN IN776/DEL/85A patent/IN166513B/en unknown
- 1985-09-24 IL IL76490A patent/IL76490A/xx not_active IP Right Cessation
- 1985-09-24 ZA ZA857326A patent/ZA857326B/xx unknown
- 1985-09-24 IE IE235485A patent/IE58616B1/en not_active IP Right Cessation
- 1985-09-24 SU SU853956452A patent/SU1358785A3/ru active
- 1985-09-24 BR BR8504673A patent/BR8504673A/pt not_active IP Right Cessation
- 1985-09-24 MA MA20758A patent/MA20532A1/fr unknown
- 1985-09-24 PT PT81183A patent/PT81183B/pt not_active IP Right Cessation
- 1985-09-24 DK DK433385A patent/DK162993C/da not_active IP Right Cessation
- 1985-09-24 KR KR1019850006999A patent/KR930009794B1/ko not_active Expired - Lifetime
- 1985-09-24 ES ES547237A patent/ES8604920A1/es not_active Expired
- 1985-09-24 ZW ZW169/85A patent/ZW16985A1/xx unknown
- 1985-09-24 FI FI853662A patent/FI86718C/fi not_active IP Right Cessation
- 1985-09-24 OA OA58684A patent/OA08104A/xx unknown
- 1985-09-24 NO NO853748A patent/NO169772C/no not_active IP Right Cessation
- 1985-09-24 AU AU47822/85A patent/AU583533B2/en not_active Expired
-
1994
- 1994-07-06 JP JP6176207A patent/JP2602783B2/ja not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| EXP | Patent expired |