IL75641A - 1-methyl-4,5-dihydro-orotyl-histidyl-prolinamide,its preparation and pharmaceutical compositions comprising it - Google Patents

1-methyl-4,5-dihydro-orotyl-histidyl-prolinamide,its preparation and pharmaceutical compositions comprising it

Info

Publication number
IL75641A
IL75641A IL75641A IL7564185A IL75641A IL 75641 A IL75641 A IL 75641A IL 75641 A IL75641 A IL 75641A IL 7564185 A IL7564185 A IL 7564185A IL 75641 A IL75641 A IL 75641A
Authority
IL
Israel
Prior art keywords
orotyl
prolinamide
histidyl
dihydro
methyl
Prior art date
Application number
IL75641A
Other languages
English (en)
Other versions
IL75641A0 (en
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB08417541A external-priority patent/GB2161486A/en
Priority claimed from GB858509929A external-priority patent/GB8509929D0/en
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of IL75641A0 publication Critical patent/IL75641A0/xx
Publication of IL75641A publication Critical patent/IL75641A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IL75641A 1984-07-10 1985-06-26 1-methyl-4,5-dihydro-orotyl-histidyl-prolinamide,its preparation and pharmaceutical compositions comprising it IL75641A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB08417541A GB2161486A (en) 1984-07-10 1984-07-10 Novel 1-methyl-4,5-dihydroorotic acid derivative and processes for preparing the same
GB858509929A GB8509929D0 (en) 1985-04-18 1985-04-18 Pharmaceutical composition

Publications (2)

Publication Number Publication Date
IL75641A0 IL75641A0 (en) 1985-10-31
IL75641A true IL75641A (en) 1990-11-05

Family

ID=26287968

Family Applications (1)

Application Number Title Priority Date Filing Date
IL75641A IL75641A (en) 1984-07-10 1985-06-26 1-methyl-4,5-dihydro-orotyl-histidyl-prolinamide,its preparation and pharmaceutical compositions comprising it

Country Status (14)

Country Link
US (1) US4665056A (da)
EP (1) EP0168042B1 (da)
KR (1) KR890002085B1 (da)
AU (1) AU580311B2 (da)
CA (1) CA1248698A (da)
DE (1) DE3577443D1 (da)
DK (1) DK171354B1 (da)
ES (3) ES8705463A1 (da)
FI (1) FI83525C (da)
HK (1) HK86292A (da)
HU (1) HU199876B (da)
IL (1) IL75641A (da)
MY (1) MY101747A (da)
SG (1) SG59992G (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69025272T2 (de) * 1989-11-17 1996-06-27 Takeda Chemical Industries Ltd Therapeutisches Mittel für Erkrankungen des Zentralnervensystems
EP0862429A4 (en) * 1995-10-24 2003-05-28 Gruenenthal Gmbh METHOD FOR ADJUSTING THE CIRCADIAN RHYTHM OF A MAMMAL
WO2002017954A1 (fr) * 2000-08-31 2002-03-07 Shionogi & Co., Ltd. Medicaments contre la maladie de parkinson
KR101137503B1 (ko) * 2009-07-14 2012-04-20 웰이앤씨 주식회사 고분자 고체 지지체를 이용한 히스티딜-프롤린아미드 유도체의 제조 방법
US9265458B2 (en) 2012-12-04 2016-02-23 Sync-Think, Inc. Application of smooth pursuit cognitive testing paradigms to clinical drug development
US9380976B2 (en) 2013-03-11 2016-07-05 Sync-Think, Inc. Optical neuroinformatics
KR101589910B1 (ko) 2013-12-31 2016-02-01 한밭대학교 산학협력단 결정형 α 탈티레린의 제조방법 및 결정형의 변환방법
GB201907591D0 (en) * 2019-05-29 2019-07-10 Eolas Res Limited Composition and use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3757003A (en) * 1969-12-18 1973-09-04 K Folkers Process for preparing l pyroglutamyl l histidyl l prolinamide
US3753969A (en) * 1969-12-22 1973-08-21 K Folkers Method for synthesizing pyroglutamylhistidyl-prolinamide
NL183764C (nl) * 1974-10-16 1989-01-16 Gruenenthal Gmbh Werkwijze voor de bereiding van een geneesmiddel met psychotrope of neurotrope werking en werkwijze voor de bereiding van een histidylprolineamide-derivaat.
JPS5944308B2 (ja) * 1976-03-23 1984-10-29 武田薬品工業株式会社 ペプタイド
HU180926B (en) * 1979-06-28 1983-05-30 Richter Gedeon Vegyeszet Process for preparing trh analogues,tripeptide amides infectives on the central nerve sysrhem
US4260601A (en) * 1979-10-23 1981-04-07 Nyegaard & Co. A/S Chemical compounds
GB2171101A (en) * 1985-02-20 1986-08-20 Tanabe Seiyaku Co Peptide and processes for preparation of the same

Also Published As

Publication number Publication date
AU4442185A (en) 1986-01-16
EP0168042B1 (en) 1990-05-02
FI852533L (fi) 1986-01-11
ES552699A0 (es) 1987-10-16
ES557144A0 (es) 1987-08-16
HK86292A (en) 1992-11-13
DE3577443D1 (de) 1990-06-07
CA1248698A (en) 1989-01-10
HU199876B (en) 1990-03-28
ES8705463A1 (es) 1987-05-01
IL75641A0 (en) 1985-10-31
MY101747A (en) 1992-01-17
ES545053A0 (es) 1987-05-01
DK313785D0 (da) 1985-07-09
ES8707738A1 (es) 1987-08-16
FI83525B (fi) 1991-04-15
FI852533A0 (fi) 1985-06-27
DK313785A (da) 1986-01-11
KR860001102A (ko) 1986-02-22
FI83525C (fi) 1991-07-25
EP0168042A2 (en) 1986-01-15
AU580311B2 (en) 1989-01-12
HUT38369A (en) 1986-05-28
US4665056A (en) 1987-05-12
SG59992G (en) 1992-09-04
KR890002085B1 (ko) 1989-06-16
ES8800208A1 (es) 1987-10-16
EP0168042A3 (en) 1987-09-30
DK171354B1 (da) 1996-09-16

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Legal Events

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KB Patent renewed
KB Patent renewed
EXP Patent expired