IL74919A - Preparation of 3-cyano-4-aminoacetophenones - Google Patents
Preparation of 3-cyano-4-aminoacetophenonesInfo
- Publication number
- IL74919A IL74919A IL74919A IL7491985A IL74919A IL 74919 A IL74919 A IL 74919A IL 74919 A IL74919 A IL 74919A IL 7491985 A IL7491985 A IL 7491985A IL 74919 A IL74919 A IL 74919A
- Authority
- IL
- Israel
- Prior art keywords
- cyano
- general formula
- aminoacetophenones
- preparation
- reaction mixture
- Prior art date
Links
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 abstract 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- WQDUMFSSJAZKTM-UHFFFAOYSA-N Sodium methoxide Chemical compound [Na+].[O-]C WQDUMFSSJAZKTM-UHFFFAOYSA-N 0.000 abstract 2
- 239000011541 reaction mixture Substances 0.000 abstract 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052731 fluorine Chemical group 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1. Process for preparing 3-cyano-4-amino-acetophenones of general formula see diagramm : EP0158932,P4,F1 wherein R represents a hydrogen or fluorine atom, characterized in that a 3-cyano-4-acetamino-acetophenone of general formula see diagramm : EP0158932,P4,F2 wherein R is defined as hereinbefore, is saponified with potassium hydroxide, sodium hydroxide, potassium or sodium methoxide in the presence of methanol as solvent at temperatures up to the boiling point of the reaction mixture and the compound of general formula I is isolated from the reaction mixture.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3414628A DE3414628C1 (en) | 1984-04-18 | 1984-04-18 | Process for the preparation of 3-cyano-4-aminoacetophenones |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL74919A0 IL74919A0 (en) | 1985-08-30 |
| IL74919A true IL74919A (en) | 1988-10-31 |
Family
ID=6233895
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL74919A IL74919A (en) | 1984-04-18 | 1985-04-16 | Preparation of 3-cyano-4-aminoacetophenones |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0158932B1 (en) |
| JP (1) | JPH0625098B2 (en) |
| AT (1) | ATE26259T1 (en) |
| AU (1) | AU571079B2 (en) |
| DE (2) | DE3414628C1 (en) |
| ES (1) | ES542338A0 (en) |
| HK (1) | HK97090A (en) |
| HU (1) | HU193109B (en) |
| IL (1) | IL74919A (en) |
| NZ (1) | NZ211831A (en) |
| SG (1) | SG25490G (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2700469C (en) | 2007-10-11 | 2016-11-15 | Cube Investments Limited | Capacitive probes and sensors, and applications therefor, and multimode wireless devices |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2354961C2 (en) * | 1973-11-02 | 1983-02-10 | Dr. Karl Thomae Gmbh, 7950 Biberach | Process for the preparation of aminophenylethanolamines |
| DE2337951C2 (en) * | 1973-07-26 | 1984-07-26 | Hoechst Ag, 6230 Frankfurt | Process for the preparation of 4-amino-2,5-dialkoxybenzonitriles |
| CH584716A5 (en) * | 1973-12-15 | 1977-02-15 | Ciba Geigy Ag | |
| US4407819A (en) * | 1980-08-25 | 1983-10-04 | American Cyanamid Company | Phenylethanolamine derivatives and acid addition salts thereof for the depression of fat deposition in warm blooded animals |
-
1984
- 1984-04-18 DE DE3414628A patent/DE3414628C1/en not_active Expired
-
1985
- 1985-04-03 EP EP85104068A patent/EP0158932B1/en not_active Expired
- 1985-04-03 AT AT85104068T patent/ATE26259T1/en not_active IP Right Cessation
- 1985-04-03 DE DE8585104068T patent/DE3560108D1/en not_active Expired
- 1985-04-16 IL IL74919A patent/IL74919A/en not_active IP Right Cessation
- 1985-04-17 JP JP60080451A patent/JPH0625098B2/en not_active Expired - Lifetime
- 1985-04-17 AU AU41356/85A patent/AU571079B2/en not_active Ceased
- 1985-04-17 ES ES542338A patent/ES542338A0/en active Granted
- 1985-04-17 NZ NZ211831A patent/NZ211831A/en unknown
- 1985-04-17 HU HU851435A patent/HU193109B/en not_active IP Right Cessation
-
1990
- 1990-03-30 SG SG254/90A patent/SG25490G/en unknown
- 1990-11-22 HK HK970/90A patent/HK97090A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPS60233046A (en) | 1985-11-19 |
| HU193109B (en) | 1987-08-28 |
| IL74919A0 (en) | 1985-08-30 |
| SG25490G (en) | 1990-09-07 |
| EP0158932B1 (en) | 1987-04-01 |
| AU4135685A (en) | 1985-10-24 |
| EP0158932A1 (en) | 1985-10-23 |
| JPH0625098B2 (en) | 1994-04-06 |
| DE3414628C1 (en) | 1985-06-27 |
| DE3560108D1 (en) | 1987-05-07 |
| ES8603386A1 (en) | 1985-12-16 |
| HUT37592A (en) | 1986-01-23 |
| ATE26259T1 (en) | 1987-04-15 |
| ES542338A0 (en) | 1985-12-16 |
| AU571079B2 (en) | 1988-03-31 |
| HK97090A (en) | 1990-11-30 |
| NZ211831A (en) | 1988-03-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |