IL71988A - 8beta-(1-pyrazolyl)methylergoline derivatives and acid addition salts thereof,their preparation and pharmaceutical compositions containing them - Google Patents

8beta-(1-pyrazolyl)methylergoline derivatives and acid addition salts thereof,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL71988A
IL71988A IL8471988A IL7198884A IL71988A IL 71988 A IL71988 A IL 71988A IL 8471988 A IL8471988 A IL 8471988A IL 7198884 A IL7198884 A IL 7198884A IL 71988 A IL71988 A IL 71988A
Authority
IL
Israel
Prior art keywords
8beta
methylergoline
pyrazolyl
derivatives
preparation
Prior art date
Application number
IL8471988A
Other languages
English (en)
Other versions
IL71988A0 (en
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of IL71988A0 publication Critical patent/IL71988A0/xx
Publication of IL71988A publication Critical patent/IL71988A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL8471988A 1983-06-03 1984-06-01 8beta-(1-pyrazolyl)methylergoline derivatives and acid addition salts thereof,their preparation and pharmaceutical compositions containing them IL71988A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU832001A HU190105B (en) 1983-06-03 1983-06-03 Process for production of pirazolyl-methyl-ergolin- derivatives and their acid additional salts

Publications (2)

Publication Number Publication Date
IL71988A0 IL71988A0 (en) 1984-10-31
IL71988A true IL71988A (en) 1987-01-30

Family

ID=10957235

Family Applications (1)

Application Number Title Priority Date Filing Date
IL8471988A IL71988A (en) 1983-06-03 1984-06-01 8beta-(1-pyrazolyl)methylergoline derivatives and acid addition salts thereof,their preparation and pharmaceutical compositions containing them

Country Status (15)

Country Link
US (1) US4632928A (da)
EP (1) EP0128479B1 (da)
JP (1) JPS6084286A (da)
AR (1) AR240323A1 (da)
AT (1) ATE55129T1 (da)
AU (1) AU569518B2 (da)
CA (1) CA1252086A (da)
DE (1) DE3482854D1 (da)
DK (1) DK162050C (da)
ES (1) ES8800940A1 (da)
FI (1) FI80272C (da)
GR (1) GR82419B (da)
HU (1) HU190105B (da)
IL (1) IL71988A (da)
ZA (1) ZA844162B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2173189B (en) * 1985-02-21 1988-04-27 Maruko Pharmaceutical Co Ergoline derivatives and salts thereof and pharmaceutical compositions thereof
GB8702364D0 (en) * 1987-02-03 1987-03-11 Erba Farmitalia Ergolinyl heterocycles
GB9603226D0 (en) * 1996-02-15 1996-04-17 Pharmacia Spa Heterocyclyl-ergoline derivatives
US6369089B1 (en) 2000-09-14 2002-04-09 Allergan Sales, Inc. Interheteroaryl 7-oxabicyclic [2.2.1]heptane oxazoles as prostaglandin F2α antagonists
US6407250B1 (en) 2000-09-14 2002-06-18 Allergan Sales, Inc. Interphenylene 7-oxabicyclic [2.2.1] heptane oxazoles as prostaglandin F2a antagonists
US6511999B2 (en) 2000-09-14 2003-01-28 Allergan, Inc. Interheteroaryl 7-oxabicyclic [2.2.1]heptane oxazoles as prostaglandin F2α antagonists
US7045634B2 (en) * 2003-09-05 2006-05-16 Allergan, Inc. Prostamide receptor antagonists
CA2757480A1 (en) * 2009-04-02 2010-10-07 Allergan, Inc. Prostaglandin e receptor antagonists

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1695752C3 (de) * 1966-07-29 1974-06-06 Societa Farmaceutici Italia, Mailand (Italien) 1 ,ö-Dimethyl-ebeta-N-carbobenzoxyaminomethyl-2,3-dihydro-1 Oalpha-ergolin und ein Verfahren zu seiner Herstellung
US4134987A (en) * 1976-01-14 1979-01-16 Huppatz John L Compounds and compositions
HU178396B (en) * 1978-03-20 1982-04-28 Vianova Kunstharz Ag Process for producing new 8-beta-hydrazion-methyl-ergoline-and -ergolene derivatives
GB2056437A (en) * 1979-08-07 1981-03-18 Erba Farmitalia Secoergoline derivatives
GB2120242A (en) * 1982-04-30 1983-11-30 Erba Farmitalia Ergoline derivatives

Also Published As

Publication number Publication date
FI842233A0 (fi) 1984-06-04
DK273884A (da) 1984-12-04
AU569518B2 (en) 1988-02-04
GR82419B (da) 1984-12-13
ES8800940A1 (es) 1987-12-01
ZA844162B (en) 1984-12-24
JPS6084286A (ja) 1985-05-13
DK162050B (da) 1991-09-09
EP0128479B1 (en) 1990-08-01
DK273884D0 (da) 1984-06-01
EP0128479A3 (en) 1985-10-30
EP0128479A2 (en) 1984-12-19
CA1252086A (en) 1989-04-04
FI842233A (fi) 1984-12-04
AR240323A1 (es) 1990-03-30
DK162050C (da) 1992-02-10
US4632928A (en) 1986-12-30
FI80272C (fi) 1990-05-10
AU2903284A (en) 1984-12-06
HU190105B (en) 1986-08-28
ES533086A0 (es) 1987-12-01
HUT34748A (en) 1985-04-28
DE3482854D1 (de) 1990-09-06
IL71988A0 (en) 1984-10-31
ATE55129T1 (de) 1990-08-15
JPH0342274B2 (da) 1991-06-26
FI80272B (fi) 1990-01-31

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