IL70866A - Charge modified microporous membrane for immobilization of macromolecules,method for its use and solid phase assay system using it - Google Patents

Charge modified microporous membrane for immobilization of macromolecules,method for its use and solid phase assay system using it

Info

Publication number
IL70866A
IL70866A IL70866A IL7086684A IL70866A IL 70866 A IL70866 A IL 70866A IL 70866 A IL70866 A IL 70866A IL 7086684 A IL7086684 A IL 7086684A IL 70866 A IL70866 A IL 70866A
Authority
IL
Israel
Prior art keywords
macromolecules
immobilization
solid phase
microporous membrane
assay system
Prior art date
Application number
IL70866A
Other languages
English (en)
Other versions
IL70866A0 (en
Original Assignee
Univ Yale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23844591&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL70866(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Yale filed Critical Univ Yale
Publication of IL70866A0 publication Critical patent/IL70866A0/xx
Publication of IL70866A publication Critical patent/IL70866A/xx

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0081—After-treatment of organic or inorganic membranes
    • B01D67/0093—Chemical modification
    • B01D67/00931—Chemical modification by introduction of specific groups after membrane formation, e.g. by grafting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D57/00—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C
    • B01D57/02—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C by electrophoresis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/06—Organic material
    • B01D71/56—Polyamides, e.g. polyester-amides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/3212—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/328—Polymers on the carrier being further modified
    • B01J20/3282—Crosslinked polymers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2323/00—Details relating to membrane preparation
    • B01D2323/30—Cross-linking

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Inorganic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Manufacturing & Machinery (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Transplantation (AREA)
  • Electrochemistry (AREA)
  • Environmental & Geological Engineering (AREA)
  • Peptides Or Proteins (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
IL70866A 1983-02-07 1984-02-03 Charge modified microporous membrane for immobilization of macromolecules,method for its use and solid phase assay system using it IL70866A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/464,609 US4512896A (en) 1983-02-07 1983-02-07 Transfer of macromolecules from a chromatographic substrate to an immobilizing matrix

Publications (2)

Publication Number Publication Date
IL70866A0 IL70866A0 (en) 1984-05-31
IL70866A true IL70866A (en) 1987-09-16

Family

ID=23844591

Family Applications (1)

Application Number Title Priority Date Filing Date
IL70866A IL70866A (en) 1983-02-07 1984-02-03 Charge modified microporous membrane for immobilization of macromolecules,method for its use and solid phase assay system using it

Country Status (9)

Country Link
US (1) US4512896A (de)
EP (1) EP0138841B1 (de)
JP (1) JPS60501126A (de)
AU (1) AU577276B2 (de)
CA (1) CA1207737A (de)
DE (2) DE3486313T2 (de)
FR (1) FR2540629B1 (de)
IL (1) IL70866A (de)
WO (1) WO1984003055A1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4601828A (en) * 1983-02-07 1986-07-22 Yale University Transfer of macromolecules from a chromatographic substrate to an immobilizing matrix
USRE34457E (en) * 1983-12-28 1993-11-30 Daicel Chemical Industries, Inc. Separating agent
USRE38435E1 (en) * 1983-12-28 2004-02-24 Daicel Chemical Industries, Ltd. Separating agent
JPS60142930A (ja) * 1983-12-28 1985-07-29 Daicel Chem Ind Ltd 分離剤
FR2586689B1 (fr) * 1985-09-02 1990-06-08 Plant Genetic Systems Nv Moyens et procedes de transfert de proteines sur une surface receptrice supportee
EP0214909A1 (de) * 1985-09-02 1987-03-18 Plant Genetic Systems N.V. Mittel und Verfahren zur Übertragung von Proteinen und/oder Nukleinsäuren auf eine unterstützte Rezeptoroberfläche
US4806546A (en) * 1985-09-30 1989-02-21 Miles Inc. Immobilization of nucleic acids on derivatized nylon supports
US5665216A (en) * 1986-10-21 1997-09-09 Northeastern University Capillary column for high performance electrophoretic separation and detection of SDS proteins and system and using the same
US4997537A (en) * 1986-10-21 1991-03-05 Northeastern University High performance microcapillary gel electrophoresis
DE3736087C2 (de) * 1987-10-24 1997-03-06 Serva Feinbiochem Gmbh & Co Gewebe zur Herstellung von Elektrophoresegelen
US5114585A (en) * 1988-03-01 1992-05-19 Gelman Sciences, Inc. Charged porous filter
EP0436547B1 (de) * 1988-05-10 1994-11-30 E.I. Du Pont De Nemours And Company Verfahren zum schnellen nachweis von nukleinsäuren
US5374524A (en) * 1988-05-10 1994-12-20 E. I. Du Pont De Nemours And Company Solution sandwich hybridization, capture and detection of amplified nucleic acids
US5004543A (en) * 1988-06-21 1991-04-02 Millipore Corporation Charge-modified hydrophobic membrane materials and method for making the same
US5075220A (en) * 1988-10-07 1991-12-24 Eastman Kodak Company Determination of a chlamydial or gonococcal antigen using a positively-charged ionically binding support
US5004806A (en) * 1988-10-17 1991-04-02 Molecular Devices Corporation Nitrocellulose filtration to remove proteins from polynucleotides
US5683916A (en) * 1988-10-31 1997-11-04 Hemasure Inc. Membrane affinity apparatus and purification methods related thereto
US4957620A (en) * 1988-11-15 1990-09-18 Hoechst Celanese Corporation Liquid chromatography using microporous hollow fibers
US4981591A (en) * 1989-04-07 1991-01-01 Cuno, Incorporated Cationic charge modified filter media
GB8921818D0 (en) * 1989-09-27 1989-11-08 Astromed Ltd Treatment of carbohydrates
US5151189A (en) * 1990-09-17 1992-09-29 Gelman Sciences, Inc. Cationic charge modified microporous membrane
US5269931A (en) * 1990-09-17 1993-12-14 Gelman Sciences Inc. Cationic charge modified microporous membranes
US5543054A (en) * 1993-11-24 1996-08-06 Millipore Corporation Method and apparatus for covalent immobilization of charge- conjugated carbohydrate molecules
US5728301A (en) * 1994-09-29 1998-03-17 Truett; William L. Apparatus and method for thin layer chromatography
US5714359A (en) * 1995-10-12 1998-02-03 The University Of Akron Apparatus and method for electrostatic endothelial cell seeding in a vascular prosthesis
US6010573A (en) * 1998-07-01 2000-01-04 Virginia Commonwealth University Apparatus and method for endothelial cell seeding/transfection of intravascular stents
JP2000180442A (ja) * 1998-12-15 2000-06-30 Fuji Photo Film Co Ltd 血液濾過器
US6780327B1 (en) 1999-02-25 2004-08-24 Pall Corporation Positively charged membrane
US6680208B1 (en) * 1999-11-19 2004-01-20 Becton, Dickinson And Company Rapid protein identification using antibody mixtures
JP2004532981A (ja) * 2001-04-10 2004-10-28 チルドレンズ メディカル センター コーポレーション タンパク質−タンパク質相互作用の解析および標識の方法
US20030038081A1 (en) * 2001-08-14 2003-02-27 I-Fan Wang High strength asymmetric cellulosic membrane
US20030036085A1 (en) * 2002-08-19 2003-02-20 Salinaro Richard F Membranes
EP2821135A1 (de) * 2004-02-05 2015-01-07 EMD Millipore Corporation Poröses Adsorptions- oder Chromatographiemedium
CA2576221A1 (en) * 2004-08-13 2006-02-16 Mcmaster University Composite material comprising a non-crosslinked gel polymer
CN100548455C (zh) 2004-09-30 2009-10-14 麦克马斯特大学 包括层状亲水性涂层的复合材料
GB0702504D0 (en) * 2007-02-09 2007-03-21 Ge Healthcare Bio Sciences Ab Cross-linked cellulose membranes
US9433922B2 (en) * 2007-08-14 2016-09-06 Emd Millipore Corporation Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same
US20090130738A1 (en) * 2007-11-19 2009-05-21 Mikhail Kozlov Media for membrane ion exchange chromatography
US8277649B2 (en) 2009-12-14 2012-10-02 General Electric Company Membranes and associated methods for purification of antibodies
JP7295943B2 (ja) * 2019-04-08 2023-06-21 旭化成メディカル株式会社 タンパク質含有溶液精製用ポリアミド媒体及びその製造方法
CN111675825B (zh) * 2020-06-09 2022-06-24 大连工业大学 一种附有胰蛋白酶的微孔膜的制备方法及其在蛋白水解中的应用

Family Cites Families (20)

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NL110447C (de) 1957-09-05
US2926154A (en) 1957-09-05 1960-02-23 Hercules Powder Co Ltd Cationic thermosetting polyamide-epichlorohydrin resins and process of making same
US3224986A (en) 1962-04-18 1965-12-21 Hercules Powder Co Ltd Cationic epichlorohydrin modified polyamide reacted with water-soluble polymers
DE1792083A1 (de) * 1968-07-19 1971-04-29 Merck Anlagen Gmbh Zweischichtenplatte und ihre Verwendung zur duennschichtchromatographischen Auftrennung von Aminosaeuren
US3769968A (en) 1971-11-22 1973-11-06 L Blount Speculum
JPS4887119A (de) 1972-02-24 1973-11-16
US3875044A (en) * 1972-06-09 1975-04-01 Marine Colloids Inc Hydratable gel sheets
US3878100A (en) * 1973-02-01 1975-04-15 Marine Colloids Inc Separation medium
US3876738A (en) 1973-07-18 1975-04-08 Amf Inc Process for producing microporous films and products
US3928517A (en) 1973-12-26 1975-12-23 Amf Inc Quench bath regeneration system for microporous film production
GB2036081B (en) * 1977-06-15 1982-08-25 Nat Res Dev Membrane electrophoresis
NZ190436A (en) 1978-05-15 1981-12-15 Pall Corp Preparation of skinless hydrophilic alcohol insoluble polyamide membranes membranes casting resin solutions
JPS54155892A (en) * 1978-05-29 1979-12-08 Ohashi Mochihiko Device for concentration electrophoresis
JPS56115727A (en) * 1980-02-19 1981-09-11 Kuraray Co Ltd Carrier for immobilizing physiologically active substance
US4357311A (en) * 1980-10-03 1982-11-02 Warner-Lambert Company Substrate for immunoassay and means of preparing same
JPS6332093B2 (de) * 1980-10-27 1988-06-28 Kyuno Inc
CH649718A5 (de) * 1981-03-25 1985-06-14 Aligena Ag Verfahren zur herstellung von semipermeablen membranen aus polymeren auf acrylnitrilbasis, die nach diesem verfahren hergestellten membranen und ihre verwendung.
US4473475A (en) 1981-05-29 1984-09-25 Amf Inc. Charge modified microporous membrane, process for charge modifying said membrane, and process for filtration of fluids
US4415428A (en) * 1982-01-27 1983-11-15 Fmc Corporation Support for electrophoresis and method of producing same
NL8203102A (nl) * 1982-08-04 1984-03-01 Katholieke Universiteit Facult Papier voor rna-blotting; werkwijze voor het maken daarvan; toepassingen van het papier.

Also Published As

Publication number Publication date
JPH0376868B2 (de) 1991-12-06
CA1207737A (en) 1986-07-15
DE3486313D1 (de) 1994-07-07
FR2540629B1 (fr) 1989-09-22
FR2540629A1 (fr) 1984-08-10
JPS60501126A (ja) 1985-07-18
DE3486313T2 (de) 1994-11-10
AU577276B2 (en) 1988-09-22
EP0138841B1 (de) 1993-10-20
US4512896A (en) 1985-04-23
WO1984003055A1 (en) 1984-08-16
DE3486231D1 (de) 1993-11-25
IL70866A0 (en) 1984-05-31
EP0138841A4 (de) 1987-12-01
EP0138841A1 (de) 1985-05-02
AU2497884A (en) 1984-08-30
DE3486231T2 (de) 1994-04-14

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Legal Events

Date Code Title Description
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees