IL69721A0 - Imidazo(1,2-a)quinolines - Google Patents
Imidazo(1,2-a)quinolinesInfo
- Publication number
- IL69721A0 IL69721A0 IL69721A IL6972183A IL69721A0 IL 69721 A0 IL69721 A0 IL 69721A0 IL 69721 A IL69721 A IL 69721A IL 6972183 A IL6972183 A IL 6972183A IL 69721 A0 IL69721 A0 IL 69721A0
- Authority
- IL
- Israel
- Prior art keywords
- group
- alkyl group
- image
- formula
- alkoxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Anesthesiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Luminescent Compositions (AREA)
Abstract
Imidazo[1,2-a]quinolines of formula I <IMAGE> [wherein R1 represents a hydrogen, chlorine or bromine atom; R2 represents a benzoyl group or a group of formula <IMAGE> or <IMAGE> where R6 and R7 represent alkyl groups, R8 represents a hydrogen atom or an alkyl group and Ph represents a phenyl group; R3 represents a hydrogen atom or an alkyl group; R4 represents an alkoxy, hydroxy, acyloxy or alkyl group; and R5 represents an alkyl group; provided that R1 and R3 do not both represent hydrogen atoms when R2 represents a benzoyl group and R4 represents an alkoxy group] and salts thereof have value in the treatment of anxiety and distress. Intermediates of formula V <IMAGE> (wherein R1, R3 and R5 are as defined above and R4 represents an alkoxy, acyloxy or alkyl group) and salts thereof may be used in their preparation.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8228069 | 1982-10-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL69721A0 true IL69721A0 (en) | 1983-12-30 |
| IL69721A IL69721A (en) | 1987-03-31 |
Family
ID=10533302
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL69721A IL69721A (en) | 1982-10-01 | 1983-09-14 | (7-ethyl-5-methoxy-4-methyl-imidazo(1,2-a)quinolin-2-yl)phenylmethanone,its preparation and pharmaceutical compositions containing it |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0107988B1 (en) |
| JP (1) | JPS5978188A (en) |
| AT (1) | ATE28646T1 (en) |
| AU (1) | AU564997B2 (en) |
| CA (1) | CA1206475A (en) |
| DE (1) | DE3372771D1 (en) |
| DK (1) | DK454783A (en) |
| ES (1) | ES8704944A1 (en) |
| FI (1) | FI76335C (en) |
| GB (1) | GB2127824B (en) |
| GR (1) | GR79396B (en) |
| HU (1) | HU189750B (en) |
| IE (1) | IE56052B1 (en) |
| IL (1) | IL69721A (en) |
| PT (1) | PT77436B (en) |
| ZA (1) | ZA836701B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP0700395A2 (en) * | 2007-06-07 | 2009-03-02 | Sanofi Aventis | Substituted [1,2,4] triazolo [1,5-a] quinolines, process for their preparation, pharmaceutical compositions thereof, and intermediates |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1596652A (en) * | 1977-01-20 | 1981-08-26 | Roussel Lab Ltd | Imidazo (1,2-a) quinoline-2-carboxylic acid and derivatives |
| GR76063B (en) * | 1981-04-03 | 1984-08-03 | Roussel Uclaf |
-
1983
- 1983-09-09 ZA ZA836701A patent/ZA836701B/en unknown
- 1983-09-14 IL IL69721A patent/IL69721A/en unknown
- 1983-09-26 JP JP58176548A patent/JPS5978188A/en active Pending
- 1983-09-29 GR GR72585A patent/GR79396B/el unknown
- 1983-09-29 DE DE8383401914T patent/DE3372771D1/en not_active Expired
- 1983-09-29 AT AT83401914T patent/ATE28646T1/en not_active IP Right Cessation
- 1983-09-29 HU HU833389A patent/HU189750B/en not_active IP Right Cessation
- 1983-09-29 EP EP83401914A patent/EP0107988B1/en not_active Expired
- 1983-09-30 IE IE2321/83A patent/IE56052B1/en unknown
- 1983-09-30 PT PT77436A patent/PT77436B/en not_active IP Right Cessation
- 1983-09-30 GB GB08326230A patent/GB2127824B/en not_active Expired
- 1983-09-30 ES ES526143A patent/ES8704944A1/en not_active Expired
- 1983-09-30 FI FI833553A patent/FI76335C/en not_active IP Right Cessation
- 1983-09-30 AU AU19823/83A patent/AU564997B2/en not_active Ceased
- 1983-09-30 CA CA000438135A patent/CA1206475A/en not_active Expired
- 1983-10-03 DK DK454783A patent/DK454783A/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| FI76335B (en) | 1988-06-30 |
| GB2127824B (en) | 1986-02-12 |
| IE56052B1 (en) | 1991-03-27 |
| CA1206475A (en) | 1986-06-24 |
| ZA836701B (en) | 1984-10-31 |
| ATE28646T1 (en) | 1987-08-15 |
| PT77436B (en) | 1986-04-17 |
| PT77436A (en) | 1983-10-01 |
| EP0107988A2 (en) | 1984-05-09 |
| DK454783D0 (en) | 1983-10-03 |
| EP0107988B1 (en) | 1987-07-29 |
| GR79396B (en) | 1984-10-22 |
| IE832321L (en) | 1984-04-01 |
| GB8326230D0 (en) | 1983-11-02 |
| JPS5978188A (en) | 1984-05-04 |
| DE3372771D1 (en) | 1987-09-03 |
| AU564997B2 (en) | 1987-09-03 |
| AU1982383A (en) | 1984-04-05 |
| FI76335C (en) | 1988-10-10 |
| ES526143A0 (en) | 1987-04-16 |
| HU189750B (en) | 1986-07-28 |
| ES8704944A1 (en) | 1987-04-16 |
| EP0107988A3 (en) | 1985-05-22 |
| GB2127824A (en) | 1984-04-18 |
| DK454783A (en) | 1984-04-02 |
| FI833553A (en) | 1984-04-02 |
| IL69721A (en) | 1987-03-31 |
| FI833553A0 (en) | 1983-09-30 |
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