DK454783D0 - PROCEDURE FOR PREPARING IMIDAZO (1,2-A) QUINOLINES AND THEIR SALTS - Google Patents

PROCEDURE FOR PREPARING IMIDAZO (1,2-A) QUINOLINES AND THEIR SALTS

Info

Publication number
DK454783D0
DK454783D0 DK4547/83A DK454783A DK454783D0 DK 454783 D0 DK454783 D0 DK 454783D0 DK 4547/83 A DK4547/83 A DK 4547/83A DK 454783 A DK454783 A DK 454783A DK 454783 D0 DK454783 D0 DK 454783D0
Authority
DK
Denmark
Prior art keywords
group
salts
alkyl group
image
quinolines
Prior art date
Application number
DK4547/83A
Other languages
Danish (da)
Other versions
DK454783A (en
Inventor
Wilfred Roger Tully
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of DK454783D0 publication Critical patent/DK454783D0/en
Publication of DK454783A publication Critical patent/DK454783A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Luminescent Compositions (AREA)

Abstract

Imidazo[1,2-a]quinolines of formula I <IMAGE> [wherein R1 represents a hydrogen, chlorine or bromine atom; R2 represents a benzoyl group or a group of formula <IMAGE> or <IMAGE> where R6 and R7 represent alkyl groups, R8 represents a hydrogen atom or an alkyl group and Ph represents a phenyl group; R3 represents a hydrogen atom or an alkyl group; R4 represents an alkoxy, hydroxy, acyloxy or alkyl group; and R5 represents an alkyl group; provided that R1 and R3 do not both represent hydrogen atoms when R2 represents a benzoyl group and R4 represents an alkoxy group] and salts thereof have value in the treatment of anxiety and distress. Intermediates of formula V <IMAGE> (wherein R1, R3 and R5 are as defined above and R4 represents an alkoxy, acyloxy or alkyl group) and salts thereof may be used in their preparation.
DK454783A 1982-10-01 1983-10-03 METHOD OF PREPARING IMIDAZO (1,2-A) QUINOLINES AND THEIR SALTS DK454783A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8228069 1982-10-01

Publications (2)

Publication Number Publication Date
DK454783D0 true DK454783D0 (en) 1983-10-03
DK454783A DK454783A (en) 1984-04-02

Family

ID=10533302

Family Applications (1)

Application Number Title Priority Date Filing Date
DK454783A DK454783A (en) 1982-10-01 1983-10-03 METHOD OF PREPARING IMIDAZO (1,2-A) QUINOLINES AND THEIR SALTS

Country Status (16)

Country Link
EP (1) EP0107988B1 (en)
JP (1) JPS5978188A (en)
AT (1) ATE28646T1 (en)
AU (1) AU564997B2 (en)
CA (1) CA1206475A (en)
DE (1) DE3372771D1 (en)
DK (1) DK454783A (en)
ES (1) ES8704944A1 (en)
FI (1) FI76335C (en)
GB (1) GB2127824B (en)
GR (1) GR79396B (en)
HU (1) HU189750B (en)
IE (1) IE56052B1 (en)
IL (1) IL69721A (en)
PT (1) PT77436B (en)
ZA (1) ZA836701B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0700395A2 (en) * 2007-06-07 2009-03-02 Sanofi Aventis Substituted [1,2,4] triazolo [1,5-a] quinolines, process for their preparation, pharmaceutical compositions thereof, and intermediates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1596652A (en) * 1977-01-20 1981-08-26 Roussel Lab Ltd Imidazo (1,2-a) quinoline-2-carboxylic acid and derivatives
GR76063B (en) * 1981-04-03 1984-08-03 Roussel Uclaf

Also Published As

Publication number Publication date
IL69721A0 (en) 1983-12-30
GB2127824B (en) 1986-02-12
EP0107988A2 (en) 1984-05-09
IE56052B1 (en) 1991-03-27
FI76335C (en) 1988-10-10
IL69721A (en) 1987-03-31
GB8326230D0 (en) 1983-11-02
EP0107988A3 (en) 1985-05-22
JPS5978188A (en) 1984-05-04
HU189750B (en) 1986-07-28
GB2127824A (en) 1984-04-18
FI833553A0 (en) 1983-09-30
GR79396B (en) 1984-10-22
ES526143A0 (en) 1987-04-16
FI833553A (en) 1984-04-02
ZA836701B (en) 1984-10-31
PT77436A (en) 1983-10-01
DE3372771D1 (en) 1987-09-03
EP0107988B1 (en) 1987-07-29
CA1206475A (en) 1986-06-24
AU564997B2 (en) 1987-09-03
ES8704944A1 (en) 1987-04-16
FI76335B (en) 1988-06-30
IE832321L (en) 1984-04-01
AU1982383A (en) 1984-04-05
PT77436B (en) 1986-04-17
DK454783A (en) 1984-04-02
ATE28646T1 (en) 1987-08-15

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment