IL69632A - 2-benzyl-3-phenoxypropylamines,their preparation and pharmaceutical compositions comprising them - Google Patents

2-benzyl-3-phenoxypropylamines,their preparation and pharmaceutical compositions comprising them

Info

Publication number
IL69632A
IL69632A IL69632A IL6963283A IL69632A IL 69632 A IL69632 A IL 69632A IL 69632 A IL69632 A IL 69632A IL 6963283 A IL6963283 A IL 6963283A IL 69632 A IL69632 A IL 69632A
Authority
IL
Israel
Prior art keywords
compound
formula
lower alkyl
group
salt
Prior art date
Application number
IL69632A
Other languages
English (en)
Other versions
IL69632A0 (en
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL69632A0 publication Critical patent/IL69632A0/xx
Publication of IL69632A publication Critical patent/IL69632A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04Formation of amino groups in compounds containing carboxyl groups
    • C07C227/06Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
    • C07C227/08Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/16Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL69632A 1982-09-07 1983-09-02 2-benzyl-3-phenoxypropylamines,their preparation and pharmaceutical compositions comprising them IL69632A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41500082A 1982-09-07 1982-09-07

Publications (2)

Publication Number Publication Date
IL69632A0 IL69632A0 (en) 1983-12-30
IL69632A true IL69632A (en) 1987-08-31

Family

ID=23643932

Family Applications (1)

Application Number Title Priority Date Filing Date
IL69632A IL69632A (en) 1982-09-07 1983-09-02 2-benzyl-3-phenoxypropylamines,their preparation and pharmaceutical compositions comprising them

Country Status (18)

Country Link
EP (1) EP0102929B1 (fi)
JP (1) JPS5973546A (fi)
AT (1) ATE28069T1 (fi)
AU (1) AU566564B2 (fi)
CA (1) CA1242728A (fi)
DD (1) DD213208A5 (fi)
DE (1) DE3372283D1 (fi)
DK (1) DK405183A (fi)
ES (4) ES8506582A1 (fi)
FI (1) FI83632C (fi)
GR (1) GR78936B (fi)
HU (1) HU194157B (fi)
IE (1) IE55906B1 (fi)
IL (1) IL69632A (fi)
NO (1) NO157975C (fi)
NZ (1) NZ205509A (fi)
PT (1) PT77291B (fi)
ZA (1) ZA836597B (fi)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1417174A2 (en) * 2001-08-08 2004-05-12 Neurosearch A/S Substituted amine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1237352A (en) * 1969-01-03 1971-06-30 Ct Europ De Rech S Mauvernay Substituted propylamines
GB1343527A (en) * 1971-07-30 1974-01-10 Cerm Cent Europ Rech Mauvernay Amino-propanol derivatives
FR2460919A1 (fr) * 1979-07-11 1981-01-30 Prod Synthese Ste Indle Amino-ethers oxydes, leur procede de preparation et leur application en therapeutique

Also Published As

Publication number Publication date
NO157975B (no) 1988-03-14
ES541260A0 (es) 1988-03-16
DD213208A5 (de) 1984-09-05
AU566564B2 (en) 1987-10-22
ES8802010A1 (es) 1988-03-16
ATE28069T1 (de) 1987-07-15
HU194157B (en) 1988-01-28
FI83632B (fi) 1991-04-30
IE832093L (en) 1984-03-07
DK405183A (da) 1984-03-08
ES525400A0 (es) 1985-08-01
JPS5973546A (ja) 1984-04-25
IL69632A0 (en) 1983-12-30
NZ205509A (en) 1987-07-31
EP0102929A3 (en) 1984-09-12
DE3372283D1 (en) 1987-08-06
ES8606244A1 (es) 1986-04-01
FI83632C (fi) 1991-08-12
AU1874683A (en) 1984-03-15
FI833150A0 (fi) 1983-09-05
DK405183D0 (da) 1983-09-06
ES541259A0 (es) 1986-12-16
ES8506582A1 (es) 1985-08-01
CA1242728A (en) 1988-10-04
IE55906B1 (en) 1991-02-14
EP0102929B1 (de) 1987-07-01
ZA836597B (en) 1984-04-25
PT77291A (en) 1983-10-01
EP0102929A2 (de) 1984-03-14
ES8702335A1 (es) 1986-12-16
GR78936B (fi) 1984-10-02
FI833150A (fi) 1984-03-08
NO157975C (no) 1988-06-28
ES541258A0 (es) 1986-04-01
PT77291B (en) 1986-07-14
NO833178L (no) 1984-03-08

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