IL68130A0 - Pyridine derivatives,processes for their preparation,pharmaceutical compositions containing them and their use as histamine h2-antagonists - Google Patents

Pyridine derivatives,processes for their preparation,pharmaceutical compositions containing them and their use as histamine h2-antagonists

Info

Publication number
IL68130A0
IL68130A0 IL68130A IL6813083A IL68130A0 IL 68130 A0 IL68130 A0 IL 68130A0 IL 68130 A IL68130 A IL 68130A IL 6813083 A IL6813083 A IL 6813083A IL 68130 A0 IL68130 A0 IL 68130A0
Authority
IL
Israel
Prior art keywords
histamine
antagonists
processes
preparation
pharmaceutical compositions
Prior art date
Application number
IL68130A
Other languages
English (en)
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of IL68130A0 publication Critical patent/IL68130A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/32—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/58—Amidines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
IL68130A 1982-03-17 1983-03-15 Pyridine derivatives,processes for their preparation,pharmaceutical compositions containing them and their use as histamine h2-antagonists IL68130A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8207835 1982-03-17
GB8209540 1982-03-31

Publications (1)

Publication Number Publication Date
IL68130A0 true IL68130A0 (en) 1983-06-15

Family

ID=26282275

Family Applications (1)

Application Number Title Priority Date Filing Date
IL68130A IL68130A0 (en) 1982-03-17 1983-03-15 Pyridine derivatives,processes for their preparation,pharmaceutical compositions containing them and their use as histamine h2-antagonists

Country Status (17)

Country Link
US (3) US4551466A (da)
EP (2) EP0089765A3 (da)
AU (2) AU1254283A (da)
CA (1) CA1192191A (da)
DD (1) DD206994A5 (da)
DE (1) DE3366369D1 (da)
DK (2) DK123083A (da)
ES (1) ES520709A0 (da)
FI (1) FI830891L (da)
GR (2) GR77155B (da)
IL (1) IL68130A0 (da)
JO (1) JO1244B1 (da)
NO (1) NO830932L (da)
PL (1) PL241052A1 (da)
PT (1) PT76395B (da)
RO (1) RO85384B (da)
ZW (1) ZW6883A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1275097A (en) * 1984-10-02 1990-10-09 Fujio Nohara Pyridyloxy derivatives
ATE496032T1 (de) 1999-02-24 2011-02-15 Hoffmann La Roche 4-phenylpyridinderivate und deren verwendung als nk-1 rezeptorantagonisten
US6436972B1 (en) 2000-04-10 2002-08-20 Dalhousie University Pyridones and their use as modulators of serine hydrolase enzymes
TWI280239B (en) 2003-07-15 2007-05-01 Hoffmann La Roche Process for preparation of pyridine derivatives
US7423147B2 (en) 2004-03-31 2008-09-09 Janssen Pharmaceutical, N.V. Pyridine compounds as histamine H3 modulators
DK1928427T3 (da) 2005-09-23 2010-03-08 Hoffmann La Roche Hidtil ukendt dosisformulering
CA2653940C (en) 2006-05-30 2015-07-14 Janssen Pharmaceutica N.V. Substituted pyridyl amide compounds as modulators of the histamine h3 receptor
CA2706328C (en) 2007-11-20 2016-04-19 Janssen Pharmaceutica N.V. Cycloalkyloxy- and heterocycloalkyloxypyridine compounds as modulators of the histamine h3 receptor
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1431589A (en) * 1973-07-13 1976-04-07 Smith Kline French Lab Ureas, thioureas and guanidines n,n-disubstituted by heterocyclo- alkylene and/or heterocycloalkylenethioalkylene groups
DE2835695A1 (de) * 1977-08-29 1979-03-15 Yamanouchi Pharma Co Ltd Neue heterocyclische verbindungen, verfahren zu ihrer herstellung und arzneimittel, die diese enthalten
JPS5444660A (en) * 1977-08-29 1979-04-09 Yamanouchi Pharmaceut Co Ltd Heterocyclic compound and its preparation
AR228941A1 (es) * 1978-04-26 1983-05-13 Glaxo Group Ltd Procedimiento para preparar nuevos derivados de 3,5-diamino-1,2,4-triazol que son activos contra receptores histaminicos
IL57415A (en) * 1978-05-30 1984-08-31 Smith Kline French Lab Nitropyrrole compounds,process for preparing them and pharmaceutical compositions containing them
US4250316A (en) * 1978-11-24 1981-02-10 Bristol-Myers Company Pyridyl guanidine anti-ulcer agents
GB2063874B (en) * 1979-10-22 1983-09-28 Glaxo Group Ltd Triazole derivatives processes for the preparation thereof and pharmaceutical compositions containing them
EP0029303B1 (en) * 1979-10-22 1985-01-30 Glaxo Group Limited 1,2,4-triazole derivatives, processes for their production and pharmaceutical compositions containing them
ZW21281A1 (en) * 1980-10-01 1981-11-18 Smith Kline French Lab Amine derivatives
US4490533A (en) * 1980-12-22 1984-12-25 Merck & Co., Inc. Aminoalkyl pyridine derivatives
US4411899A (en) * 1981-12-21 1983-10-25 Merck & Co., Inc. Substituted derivatives of amino alkane diols as gastric secretion inhibitors

Also Published As

Publication number Publication date
GR77155B (da) 1984-09-07
DK123183A (da) 1983-09-18
EP0089153B1 (en) 1986-09-24
DE3366369D1 (en) 1986-10-30
PT76395B (en) 1985-12-05
NO830932L (no) 1983-09-19
RO85384B (ro) 1984-11-30
ES8500935A1 (es) 1984-11-01
EP0089765A2 (en) 1983-09-28
AU1254283A (en) 1983-09-22
GR77162B (da) 1984-09-10
ZW6883A1 (en) 1983-06-08
US4551466A (en) 1985-11-05
RO85384A (ro) 1984-11-25
US4574126A (en) 1986-03-04
EP0089765A3 (en) 1984-05-23
US4758576A (en) 1988-07-19
PT76395A (en) 1983-04-01
DK123083A (da) 1983-09-18
DK123083D0 (da) 1983-03-17
JO1244B1 (en) 1985-04-20
DK123183D0 (da) 1983-03-17
CA1192191A (en) 1985-08-20
ES520709A0 (es) 1984-11-01
EP0089153A2 (en) 1983-09-21
FI830891L (fi) 1983-09-18
FI830891A0 (fi) 1983-03-17
DD206994A5 (de) 1984-02-15
AU1254183A (en) 1983-09-22
PL241052A1 (en) 1984-05-21
EP0089153A3 (en) 1984-07-11

Similar Documents

Publication Publication Date Title
IL62082A0 (en) -lactam derivatives,process for the preparation thereof and pharmaceutical compositions containing them
ZA834777B (en) Imidazole derivatives,processes for their preparation,and pharmaceutical compositions thereof
IL63428A (en) 2-pyridyl thiazoline-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
IL63913A0 (en) Pyrimidone derivatives,process for their preparation,pharmaceutical compositions containing them and their use
IL62602A (en) Pyridoxine derivatives,their preparation and pharmaceutical compositions containing them
DE3161260D1 (en) Imidazole derivatives, process for their preparation and pharmaceutical compositions thereof
ZA816826B (en) Pyridine derivatives, processes for their preparation, and pharmaceutical compositions thereof
DE3062310D1 (en) Pyrimidone derivatives, processes for their preparation and pharmaceutical compositions containing them
ZA836072B (en) Desoxyuridine derivatives,processes for their preparation and their use as pharmaceuticals
ZA853667B (en) New benzazephine derivatives,pharmaceutical compositions containing them and processes for their preparation
DE3161238D1 (en) 20-deoxyrosaramicin derivatives, process for their preparation and pharmaceutical compositions containing them
DE3376215D1 (en) Aminoglycoside derivatives, processes for their preparation and pharmaceutical compositions containing them
IL68130A0 (en) Pyridine derivatives,processes for their preparation,pharmaceutical compositions containing them and their use as histamine h2-antagonists
IL58676A (en) Histamine h2-antagonist pyrimid-4-one derivatives,their preparation and pharmaceutical compositions containing same
IL69735A (en) 1-phenyl-1-aminoalkyl-cyclobutane derivatives,process for their preparation and pharmaceutical compositions containing them
DE3262919D1 (en) Imidazoline derivatives, process for the preparation thereof, pharmaceutical compositions containing them and their use
DE3165733D1 (en) Pyrimidone derivatives, processes for their preparation and pharmaceutical compositions containing them
IL69392A0 (en) Nicotinamide derivatives,their preparation and pharmaceutical compositions containing them
DE3172914D1 (en) 5-amino-tetrazole derivatives, processes for their preparation and pharmaceutical compositions containing them
IL69324A0 (en) Fluoralkylated carbapenem derivatives,their preparation and pharmaceutical compositions containing them
IL69845A (en) Tetrahydropyran-3 or 4-yl-3-amino-propoxyphenyl derivatives,their preparation and pharmaceutical compositions containing them
IL64123A (en) Biphenylyloxypropoxypyrimidine derivatives,process for their preparation and pharmaceutical compositions containing them
IL62747A (en) 2-guanidinothiazole derivatives,process for the preparation thereof and pharmaceutical compositions comprising the same
IL68253A0 (en) Furan derivatives,processes for the preparation thereof,and pharmaceutical compositions containing the same
DE3176402D1 (en) Benzazol derivatives, processes for their preparation, their pharmaceutical composition and their application