IL67040A - N-nitroso-n-(beta-chloro ethyl)-carbamoyl peptides,their preparation and pharmaceutical compositions comprising them - Google Patents

N-nitroso-n-(beta-chloro ethyl)-carbamoyl peptides,their preparation and pharmaceutical compositions comprising them

Info

Publication number
IL67040A
IL67040A IL67040A IL6704082A IL67040A IL 67040 A IL67040 A IL 67040A IL 67040 A IL67040 A IL 67040A IL 6704082 A IL6704082 A IL 6704082A IL 67040 A IL67040 A IL 67040A
Authority
IL
Israel
Prior art keywords
preparation
nitroso
carbamoyl
peptides
beta
Prior art date
Application number
IL67040A
Other languages
English (en)
Other versions
IL67040A0 (en
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of IL67040A0 publication Critical patent/IL67040A0/xx
Publication of IL67040A publication Critical patent/IL67040A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0815Tripeptides with the first amino acid being basic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/595Gastrins; Cholecystokinins [CCK]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68Melanocyte-stimulating hormone [MSH]
    • C07K14/685Alpha-melanotropin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/695Corticotropin [ACTH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL67040A 1981-10-22 1982-10-21 N-nitroso-n-(beta-chloro ethyl)-carbamoyl peptides,their preparation and pharmaceutical compositions comprising them IL67040A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU813073A HU187461B (en) 1981-10-22 1981-10-22 Process for producing n-nitrozo-n-bracket-beta-chloroethyl-bracket closed-carbamoyl-peptides of citostatic activity

Publications (2)

Publication Number Publication Date
IL67040A0 IL67040A0 (en) 1983-02-23
IL67040A true IL67040A (en) 1985-11-29

Family

ID=10962415

Family Applications (1)

Application Number Title Priority Date Filing Date
IL67040A IL67040A (en) 1981-10-22 1982-10-21 N-nitroso-n-(beta-chloro ethyl)-carbamoyl peptides,their preparation and pharmaceutical compositions comprising them

Country Status (11)

Country Link
US (1) US4950651A (xx)
EP (1) EP0078167B1 (xx)
JP (1) JPS5888349A (xx)
AT (1) ATE32342T1 (xx)
DE (1) DE3278075D1 (xx)
DK (1) DK468482A (xx)
FI (1) FI77672C (xx)
GR (1) GR76768B (xx)
HU (1) HU187461B (xx)
IL (1) IL67040A (xx)
SU (3) SU1424739A3 (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6057367A (en) 1996-08-30 2000-05-02 Duke University Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically proliferating cells or to upregulate nitrosative stress defenses
GB0918579D0 (en) * 2009-10-22 2009-12-09 Imp Innovations Ltd Gadd45beta targeting agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3814746A (en) * 1970-08-05 1974-06-04 Inst Sieroterapico Milanese Se Mannich base of tetracycline and polypeptides

Also Published As

Publication number Publication date
EP0078167B1 (en) 1988-02-03
US4950651A (en) 1990-08-21
SU1586520A3 (ru) 1990-08-15
FI77672C (fi) 1989-04-10
FI823591L (fi) 1983-04-23
JPS5888349A (ja) 1983-05-26
DK468482A (da) 1983-04-23
HU187461B (en) 1986-01-28
FI77672B (fi) 1988-12-30
DE3278075D1 (de) 1988-03-10
EP0078167A1 (en) 1983-05-04
FI823591A0 (fi) 1982-10-20
ATE32342T1 (de) 1988-02-15
GR76768B (xx) 1984-09-03
SU1424739A3 (ru) 1988-09-15
SU1414851A1 (ru) 1988-08-07
IL67040A0 (en) 1983-02-23

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