IL63428A - 2-pyridyl thiazoline-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

2-pyridyl thiazoline-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL63428A
IL63428A IL63428A IL6342881A IL63428A IL 63428 A IL63428 A IL 63428A IL 63428 A IL63428 A IL 63428A IL 6342881 A IL6342881 A IL 6342881A IL 63428 A IL63428 A IL 63428A
Authority
IL
Israel
Prior art keywords
thiazoline
pyridyl
preparation
carboxylic acid
pharmaceutical compositions
Prior art date
Application number
IL63428A
Other languages
English (en)
Other versions
IL63428A0 (en
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of IL63428A0 publication Critical patent/IL63428A0/xx
Publication of IL63428A publication Critical patent/IL63428A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/081Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/16Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
    • C12P17/167Heterorings having sulfur atoms as ring heteroatoms, e.g. vitamin B1, thiamine nucleus and open chain analogs
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465Streptomyces
    • C12R2001/48Streptomyces antibioticus ; Actinomyces antibioticus
IL63428A 1980-07-28 1981-07-27 2-pyridyl thiazoline-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them IL63428A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH575580 1980-07-28
CH592580 1980-08-05

Publications (2)

Publication Number Publication Date
IL63428A0 IL63428A0 (en) 1981-10-30
IL63428A true IL63428A (en) 1984-12-31

Family

ID=25698328

Family Applications (1)

Application Number Title Priority Date Filing Date
IL63428A IL63428A (en) 1980-07-28 1981-07-27 2-pyridyl thiazoline-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them

Country Status (13)

Country Link
US (1) US4406905A (el)
EP (1) EP0045281B1 (el)
AU (1) AU548331B2 (el)
CA (1) CA1172188A (el)
DE (1) DE3170401D1 (el)
DK (1) DK160304C (el)
ES (4) ES504316A0 (el)
GB (1) GB2085873B (el)
GR (1) GR74313B (el)
IE (1) IE51430B1 (el)
IL (1) IL63428A (el)
NZ (1) NZ197840A (el)
PT (1) PT73439B (el)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU200177B (en) * 1985-06-18 1990-04-28 Biogal Gyogyszergyar Process for producing thiazolidinecarboxylic acids and pharmaceutical compositions comprising such compounds
JPS63225373A (ja) * 1986-07-24 1988-09-20 Sumitomo Pharmaceut Co Ltd 新規チアゾリジン−4−オン誘導体およびその酸付加塩
CN1030415A (zh) * 1987-02-20 1989-01-18 山之内制药株式会社 饱和的杂环碳酰胺衍生物和它的制备方法
US4992455A (en) * 1987-05-22 1991-02-12 Sumitomo Pharmaceuticals Company, Limited Thiazolidin-4-one derivatives useful for treating diseases caused by platelet activating factor
EP0325559B1 (de) * 1988-01-20 1993-12-15 Ciba-Geigy Ag Verfahren zur Herstellung von Komplexverbindungen
US5021435A (en) * 1988-01-22 1991-06-04 Sumitomo Pharmaceuticals Company, Limited Certain pyridyl-thiazolidin-4-one having anti-ulcer activity
WO1994011367A1 (en) * 1992-11-16 1994-05-26 University Of Florida Research Foundation Inc. 2-(pyrid-2'-yl)-2-thiazoline-4(s)-carboxylic acid derivatives
US5840739A (en) * 1992-11-16 1998-11-24 University Of Florida Research Foundation, Inc. Thiazoline acid derivatives
ES2172591T3 (es) * 1994-08-05 2002-10-01 Shionogi & Co Nuevo antibiotico y procedimiento de produccion de este ultimo.
US6083966A (en) 1998-08-31 2000-07-04 University Of Florida Thiazoline acid derivatives
NZ526880A (en) * 1998-09-21 2005-05-27 Univ Florida Antimalarial agents
AT500490A1 (de) * 2001-10-16 2006-01-15 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von substituierten thiazolinen und deren zwischenprodukte
ATE415387T1 (de) * 2002-05-15 2008-12-15 Genzyme Corp Verfahren zur herstellung von benzonitrilen und benzimidosäure-derivaten
WO2004031163A1 (ja) * 2002-10-01 2004-04-15 Kaneka Corporation 光学活性α−置換システインまたはその塩の製造方法並びにその合成中間体及びその製造方法
AU2003270473A1 (en) * 2003-09-09 2005-04-27 University Of Florida Desferrithiocin derivatives and their use as iron chelators
ES2732625T3 (es) 2005-04-04 2019-11-25 Univ Florida Análogos de poliéter de desferritiocina
US8324397B2 (en) 2007-03-15 2012-12-04 University Of Florida Research Foundation, Inc. Desferrithiocin polyether analogues
CN113398126A (zh) 2011-12-16 2021-09-17 佛罗里达大学研究基金会 4′-去铁硫素类似物的用途
USD736089S1 (en) 2012-06-14 2015-08-11 S.C. Johnson & Son, Inc. Bottle
USD736637S1 (en) 2012-06-14 2015-08-18 S.C. Johnson & Son, Inc. Bottle
USD722879S1 (en) 2012-06-14 2015-02-24 S.C. Johnson & Son, Inc. Bottle
US10010535B2 (en) 2013-11-22 2018-07-03 University Of Florida Research Foundation, Incorporated Desferrithiocin analogs and uses thereof
JP6688278B2 (ja) 2014-07-08 2020-04-28 ダウ アグロサイエンシィズ エルエルシー 4−アルコキシ−3−ヒドロキシピコリン酸の製造方法
MX2016017124A (es) 2014-07-08 2017-05-10 Dow Agrosciences Llc Proceso para la preparacion de acidos 3-hidroxipicolinicos.
CN107708693A (zh) 2015-04-27 2018-02-16 佛罗里达大学研究基金会 代谢程序化的金属螯合剂及其用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3592905A (en) * 1969-10-30 1971-07-13 Merck & Co Inc Therapeutic methods
CA962269A (en) * 1971-05-05 1975-02-04 Robert E. Grahame (Jr.) Thiazoles, and their use as insecticides
US3852293A (en) * 1972-06-21 1974-12-03 Uniroyal Inc 4-phenyl-2-(3-pyridyl)-thiazole carboxamides
US3842172A (en) * 1972-10-06 1974-10-15 Uniroyal Inc Pharmaceutical compositions containing a 4-substituted-2-(3-pyridyl)thiazole and methods of using same
FR2356423A1 (fr) * 1976-07-01 1978-01-27 Oeriu Simion Derives de l'acide thiazolidinecarboxylique, leur preparation et leur application comme medicaments

Also Published As

Publication number Publication date
EP0045281A1 (de) 1982-02-03
IE811697L (en) 1982-01-28
GB2085873A (en) 1982-05-06
US4406905A (en) 1983-09-27
ES514588A0 (es) 1983-10-01
IL63428A0 (en) 1981-10-30
CA1172188A (en) 1984-08-07
AU7343981A (en) 1982-02-04
DE3170401D1 (en) 1985-06-13
ES8308877A1 (es) 1983-10-01
AU548331B2 (en) 1985-12-05
DK335781A (da) 1982-01-29
ES514586A0 (es) 1983-11-01
IE51430B1 (en) 1986-12-24
PT73439B (de) 1983-06-20
EP0045281B1 (de) 1985-05-08
GB2085873B (en) 1984-03-21
ES8400425A1 (es) 1983-11-01
ES8301476A1 (es) 1982-12-01
DK160304B (da) 1991-02-25
PT73439A (de) 1981-08-01
ES8308878A1 (es) 1983-10-01
NZ197840A (en) 1985-08-30
ES504316A0 (es) 1982-12-01
ES514587A0 (es) 1983-10-01
DK160304C (da) 1991-07-29
GR74313B (el) 1984-06-22

Similar Documents

Publication Publication Date Title
IL63428A (en) 2-pyridyl thiazoline-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
IL69347A (en) Methylene-diphosphonic acid derivatives,their preparation and pharmaceutical compositions containing them
IL69601A0 (en) Naphthyridine-,quinoline-and benzoxazine-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
IL62200A (en) Piperidine derivatives,their preparation and pharmaceutical compositions containing them
IL62602A (en) Pyridoxine derivatives,their preparation and pharmaceutical compositions containing them
IL62246A (en) 2(1h)-pyridinone derivatives,their preparation and pharmaceutical compositions containing them
IL61968A0 (en) 1-(cycolohexyl)-4-aryl-4-piperidinecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
ZA816826B (en) Pyridine derivatives, processes for their preparation, and pharmaceutical compositions thereof
DE3161238D1 (en) 20-deoxyrosaramicin derivatives, process for their preparation and pharmaceutical compositions containing them
IL62912A0 (en) Penam-3-carboxylic acid derivatives,their manufacture and pharmaceutical compositions containing them
DE3169095D1 (en) 3-aminopropoxyphenyl derivatives, their preparation and pharmaceutical compositions containing them
IL62229A0 (en) Heterocyclic derivatives,their preparation and pharmaceutical compositions containing them
IL64544A (en) Quinolone derivatives,their preparation and pharmaceutical compositions containing them
IL63245A (en) 3-aminopropoxyphenyl derivatives,their preparation and pharmaceutical compositions containing them
IL69392A0 (en) Nicotinamide derivatives,their preparation and pharmaceutical compositions containing them
IL64123A (en) Biphenylyloxypropoxypyrimidine derivatives,process for their preparation and pharmaceutical compositions containing them
IL62970A0 (en) Substituted phenoxy-aminopropanol derivatives,their preparation and pharmaceutical compositions containing them
IL63174A0 (en) Dibenzindole derivatives,their preparation and pharmaceutical compositions containing them
IL63369A (en) 13-oxa-prostaglandin derivatives,their preparation and pharmaceutical compositions containing them
IL62116A (en) Benzylidenimine derivatives,their preparation and pharmaceutical compositions containing them
IL63709A (en) Pyrazine derivatives,their preparation and pharmaceutical compositions containing them
IL70084A0 (en) Pyridine derivatives,their preparation and pharmaceutical compositions containing them
IL68520A (en) 5-oxo-2-pyrrolidinepropanoic acid and derivatives thereof,their preparation and pharmaceutical compositions containing them
IL65336A0 (en) Pyridine derivatives,their preparation and pharmaceutical compositions containing them
IL64328A0 (en) Naphthyridine derivatives,their preparation and pharmaceutical compositions containing them