IL62101A - 2-(3-(4-(3-chloro-4-fluorophenyl)-1-piperazinyl)propyl)-1,2,4-triazolo(4,3-a)pyridin-3(2h)-one,its salts,their preparation and pharmaceutical compositions containing them - Google Patents

2-(3-(4-(3-chloro-4-fluorophenyl)-1-piperazinyl)propyl)-1,2,4-triazolo(4,3-a)pyridin-3(2h)-one,its salts,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL62101A
IL62101A IL62101A IL6210181A IL62101A IL 62101 A IL62101 A IL 62101A IL 62101 A IL62101 A IL 62101A IL 6210181 A IL6210181 A IL 6210181A IL 62101 A IL62101 A IL 62101A
Authority
IL
Israel
Prior art keywords
triazolo
piperazinyl
pyridin
fluorophenyl
chloro
Prior art date
Application number
IL62101A
Other languages
English (en)
Other versions
IL62101A0 (en
Original Assignee
Acraf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acraf filed Critical Acraf
Publication of IL62101A0 publication Critical patent/IL62101A0/xx
Publication of IL62101A publication Critical patent/IL62101A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL62101A 1980-04-09 1981-02-10 2-(3-(4-(3-chloro-4-fluorophenyl)-1-piperazinyl)propyl)-1,2,4-triazolo(4,3-a)pyridin-3(2h)-one,its salts,their preparation and pharmaceutical compositions containing them IL62101A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21246/80A IT1147349B (it) 1980-04-09 1980-04-09 2-parentesi quadra aperta 3-parentesi quadra aperta 4-(3-cloro-4-fluorofenil)-1-piperfrazinil parentesi quadra propil parentesi quadra chiusa-1,2,4-triazolo parentesi quadra aperta 4,3 parentesi quadra chiusa piridin-3(2h)-one

Publications (2)

Publication Number Publication Date
IL62101A0 IL62101A0 (en) 1981-03-31
IL62101A true IL62101A (en) 1984-01-31

Family

ID=11178966

Family Applications (1)

Application Number Title Priority Date Filing Date
IL62101A IL62101A (en) 1980-04-09 1981-02-10 2-(3-(4-(3-chloro-4-fluorophenyl)-1-piperazinyl)propyl)-1,2,4-triazolo(4,3-a)pyridin-3(2h)-one,its salts,their preparation and pharmaceutical compositions containing them

Country Status (21)

Country Link
US (1) US4402956A (el)
JP (1) JPS56158784A (el)
KR (1) KR840002292B1 (el)
AR (1) AR225076A1 (el)
AT (1) AT377262B (el)
AU (1) AU529605B2 (el)
BE (1) BE887547A (el)
CA (1) CA1176253A (el)
CH (1) CH652397A5 (el)
DE (1) DE3112984A1 (el)
ES (1) ES501188A0 (el)
FI (1) FI69306C (el)
FR (1) FR2480285A1 (el)
GB (1) GB2073747B (el)
GR (1) GR73620B (el)
IL (1) IL62101A (el)
IT (1) IT1147349B (el)
NL (1) NL8100998A (el)
PT (1) PT72813B (el)
SE (1) SE442201B (el)
YU (1) YU83181A (el)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001504121A (ja) * 1996-11-12 2001-03-27 セプラコール，インク． ２ｒ，４ｓ，ｒ，ｓ―および２ｓ，４ｒ，ｒ，ｓ―ヒドロキシイトラコナゾール―およびヒドロキシサパーコナゾール誘導体
JP2001504465A (ja) 1996-11-12 2001-04-03 セプラコール，インク． ２ｒ，４ｓ，ｓ，ｓ―および２ｓ，４ｒ，ｓ，ｓ―ヒドロキシイトラコナゾール
US6147077A (en) * 1999-04-29 2000-11-14 Sepracor Inc. 2R,4S-hydroxyitraconazole isomers
US8686158B2 (en) * 2008-06-05 2014-04-01 President And Fellows Of Harvard College High-valent palladium fluoride complexes and uses thereof
WO2010059943A2 (en) 2008-11-20 2010-05-27 President And Fellows Of Harvard College Fluorination of organic compounds
JP2012514655A (ja) * 2009-01-09 2012-06-28 プレジデント アンド フェローズ オブ ハーバード カレッジ フッ素含有化合物およびその使用法
CN103596931B (zh) 2011-04-12 2016-10-12 哈佛大学校长及研究员协会 有机化合物的氟化
WO2014052622A1 (en) 2012-09-26 2014-04-03 President And Fellows Of Harvard College Nickel fluorinating complexes and uses thereof
US10759764B2 (en) 2013-10-18 2020-09-01 President And Fellows Of Harvard College Fluorination of organic compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1066857B (it) * 1965-12-15 1985-03-12 Acraf Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione
FR8135M (el) * 1968-12-31 1970-08-10
US4267179A (en) * 1978-06-23 1981-05-12 Janssen Pharmaceutica, N.V. Heterocyclic derivatives of (4-phenylpiperazin-1-yl-aryloxymethyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles
UST100505I4 (en) 1980-03-17 1981-04-07 Triazolo[4,3-a]pyridin-3(2H)-ones

Also Published As

Publication number Publication date
US4402956A (en) 1983-09-06
GB2073747A (en) 1981-10-21
AU6904381A (en) 1981-10-15
CA1176253A (en) 1984-10-16
IT1147349B (it) 1986-11-19
SE442201B (sv) 1985-12-09
KR830005218A (ko) 1983-08-03
JPS56158784A (en) 1981-12-07
FR2480285A1 (fr) 1981-10-16
FI811000L (fi) 1981-10-10
YU83181A (en) 1983-12-31
DE3112984A1 (de) 1981-12-24
GB2073747B (en) 1983-09-07
CH652397A5 (it) 1985-11-15
GR73620B (el) 1984-03-26
BE887547A (fr) 1981-06-15
NL8100998A (nl) 1981-11-02
SE8102093L (sv) 1981-10-10
AU529605B2 (en) 1983-06-16
FI69306B (fi) 1985-09-30
ES8202817A1 (es) 1982-02-01
KR840002292B1 (ko) 1984-12-15
IL62101A0 (en) 1981-03-31
PT72813A (en) 1981-05-01
FR2480285B1 (el) 1984-02-24
ES501188A0 (es) 1982-02-01
ATA165081A (de) 1984-07-15
PT72813B (en) 1982-04-02
IT8021246A0 (it) 1980-04-09
AT377262B (de) 1985-02-25
AR225076A1 (es) 1982-02-15
FI69306C (fi) 1986-01-10

Similar Documents

Publication Publication Date Title
IL62494A0 (en) 3-(1-piperidinylalkyl)-4h-pyrido(1,2-a)pyrimidin-4-one derivatives,their preparation and pharmaceutical compositions containing them
IL70093A (en) Leukotriene antagonist and antiinflammatory pharmaceutical compositions containing 4-acyl-3-hydroxy phenoxyalkane derivatives,some such new derivatives and their preparation
IL63784A0 (en) Phenyl piperazine derivatives,their preparation and pharmaceutical compositions containing them
ZA815243B (en) Piperidyl derivatives of triazine copolymers,processes for their preparation and stabilised composition containing these derivatives
IL62101A (en) 2-(3-(4-(3-chloro-4-fluorophenyl)-1-piperazinyl)propyl)-1,2,4-triazolo(4,3-a)pyridin-3(2h)-one,its salts,their preparation and pharmaceutical compositions containing them
AU7452587A (en) Sustained release formulations containing 4-(1-methyl-4- piperidylidene)-4H-benzo(4,5)-cyclohepta(1,2-b)thiophen- 10(9H)-one
IL72601A (en) 1-h-imidazo(1',2':1,2)pyrrolo(3,4-b)pyridine-2,5-(3h,11bh)-dione derivatives,their preparation and herbicidal compositions containing them
IL58592A (en) 9-(3-(3,5-cis-dimethylpiperazino)propyl)carbazole and salts thereof,their preparation and pharmaceutical composition containing them
IL62229A0 (en) Heterocyclic derivatives,their preparation and pharmaceutical compositions containing them
PH15900A (en) Derivatives of 5-(pyridyl-2'-oxy)-2-nitrobenzoic acid and herbicidal compositions containing them
DE2963350D1 (en) Heterocyclic carboxamidine compounds, their preparation and pharmaceutical compositions containing them
IL60308A (en) 4-(substituted)thio-1-beta-d-ribofuranosylpyrazolo-(3,4-d)pyrimidine derivatives,their preparation and pharmaceutical compositions containing them
IL60557A0 (en) 1-benzoxepin-5(2h)-one derivatives,their preparation and phrmaceutical compositions containing them
IL65470A (en) 2-(4-phenyl-polyhhydro-piperidinyl-or pyrrolidinyl alkyl)-1,2,4-triazolo(4,3-a)pyridin-3(2h)-ones,their preparation and pharmaceutical compositions containing them
NZ190698A (en) 2-(1h-imidazol-l-yl) ethoxy derivatives of pyrazolo (3,4-b) pyridine-5-methanols
IL58229A (en) Substituted benzylidene-benzofuran-3-(2h)-one compounds,their preparation and pharmaceutical compositions containing them
IL58155A0 (en) 2h-(1)benzothiono(2,3-e)-1,2-thiazine-3-carbox-amide-1,1-dioxide derivatves their preparation and pharmaceutical compositions containing them
DE2860750D1 (en) Antithrombotic 2-(gamma-(1-piperidinyl)propyl)1,2-benzisothiazol 3-one, its pharmaceutically acceptable acid addition salts, their preparation and their compositions
IL56558A (en) 1alpha-alkyl-1-(3-(substituted amino)propyl)-1,2,3,4,6,7,12b beta-octahydro-indolo(2,3-a)quinolizines,their preparation and pharmaceutical compositions containing them
ZA803964B (en) 2-(perhydro-1,4-diazine)-pyrimido(5,4-d)pyrimidines,and salts thereof,their preparation,pharmaceutical compositions,and use thereof
IL63783A0 (en) Phenyl piperazine derivatives,their preparation and pharmaceutical compositions containing them
PT73123B (en) 4-(1-piperazinyl)-furo<3,2-c>pyridine derivatives processes for their preparation and pharmaceutical compositions containing same
IL65555A (en) 5-pyridyl-1h-pyrazolo(3,4-b)pyridin-3-amine derivatives,their preparation and pharmaceutical compositions containing them
IL64672A0 (en) Substituted tetrahydro-1,2,4-oxadiazin-5-one derivatives,their preparation and pharmaceutical compositions containing them
IL64673A0 (en) N4-substituted tetrahydro-1,2,4-oxadiazin-5-one derivatives,their preparation and pharmaceutical compositions containing them