IL61714A - Analgesic compositions comprising alpha-methyl-4-(2-thienylcarbonyl)benzeneacetic acid in combination with codeine or butorphanol - Google Patents
Analgesic compositions comprising alpha-methyl-4-(2-thienylcarbonyl)benzeneacetic acid in combination with codeine or butorphanolInfo
- Publication number
- IL61714A IL61714A IL61714A IL6171480A IL61714A IL 61714 A IL61714 A IL 61714A IL 61714 A IL61714 A IL 61714A IL 6171480 A IL6171480 A IL 6171480A IL 61714 A IL61714 A IL 61714A
- Authority
- IL
- Israel
- Prior art keywords
- thienylcarbonyl
- alpha
- methyl
- combination
- butorphanol
- Prior art date
Links
- 230000000202 analgesic effect Effects 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 3
- MDKGKXOCJGEUJW-UHFFFAOYSA-N suprofen Chemical compound C1=CC(C(C(O)=O)C)=CC=C1C(=O)C1=CC=CS1 MDKGKXOCJGEUJW-UHFFFAOYSA-N 0.000 title abstract 2
- OROGSEYTTFOCAN-DNJOTXNNSA-N codeine Chemical compound C([C@H]1[C@H](N(CC[C@@]112)C)C3)=C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC OROGSEYTTFOCAN-DNJOTXNNSA-N 0.000 title 2
- IFKLAQQSCNILHL-QHAWAJNXSA-N butorphanol Chemical compound N1([C@@H]2CC3=CC=C(C=C3[C@@]3([C@]2(CCCC3)O)CC1)O)CC1CCC1 IFKLAQQSCNILHL-QHAWAJNXSA-N 0.000 title 1
- 229960001113 butorphanol Drugs 0.000 title 1
- 229960004126 codeine Drugs 0.000 title 1
- OROGSEYTTFOCAN-UHFFFAOYSA-N hydrocodone Natural products C1C(N(CCC234)C)C2C=CC(O)C3OC2=C4C1=CC=C2OC OROGSEYTTFOCAN-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/104,495 US4315936A (en) | 1979-12-17 | 1979-12-17 | Analgesic composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL61714A true IL61714A (en) | 1985-07-31 |
Family
ID=22300801
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL61714A IL61714A (en) | 1979-12-17 | 1980-12-15 | Analgesic compositions comprising alpha-methyl-4-(2-thienylcarbonyl)benzeneacetic acid in combination with codeine or butorphanol |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US4315936A (enExample) |
| EP (1) | EP0031234B1 (enExample) |
| JP (1) | JPS5697225A (enExample) |
| AT (1) | ATE6470T1 (enExample) |
| AU (1) | AU539193B2 (enExample) |
| CA (1) | CA1161758A (enExample) |
| DE (1) | DE3066887D1 (enExample) |
| HK (1) | HK80584A (enExample) |
| IE (1) | IE50948B1 (enExample) |
| IL (1) | IL61714A (enExample) |
| NZ (1) | NZ195693A (enExample) |
| PH (1) | PH16822A (enExample) |
| SG (1) | SG50984G (enExample) |
| ZA (1) | ZA807851B (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4777174A (en) * | 1982-07-22 | 1988-10-11 | Analgesic Associates | Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same |
| US4656177A (en) * | 1982-07-22 | 1987-04-07 | Analgesic Associates | Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same |
| NL191432C (nl) * | 1982-07-22 | 1995-07-04 | Vicks Richardson | Farmaceutisch preparaat omvattende naproxen en een andere werkzame verbinding. |
| US4599342A (en) * | 1984-01-16 | 1986-07-08 | The Procter & Gamble Company | Pharmaceutical products providing enhanced analgesia |
| US4681897A (en) * | 1984-01-16 | 1987-07-21 | The Procter & Gamble Company | Pharmaceutical products providing enhanced analgesia |
| US4755532A (en) * | 1984-02-08 | 1988-07-05 | Richardson-Vicks, Inc. | Analgesic and anti-inflammatory compositions comprising diphenhydramine and methods of using same |
| US4906625A (en) * | 1984-02-08 | 1990-03-06 | Richardson-Vicks, Inc. | Analgesic and anti-inflammatory compositions comprising diphenhydramine and metyhods of using same |
| US4683243A (en) * | 1984-02-08 | 1987-07-28 | Richardson-Vicks, Inc. | Analgesic and anti-inflammatory compositions comprising diphenhydramine and methods of using same |
| US4985459A (en) * | 1984-02-08 | 1991-01-15 | Richardson-Vicks, Inc. | Analgesic and anti-inflammatory compositions comprising diphenhydramine and methods of using same |
| US4522826A (en) * | 1984-02-08 | 1985-06-11 | Richardson-Vicks Inc. | Analgesic and anti-inflammatory compositions comprising diphenhydramine and methods of using same |
| US4588580B2 (en) * | 1984-07-23 | 1999-02-16 | Alaz Corp | Transdermal administration of fentanyl and device therefor |
| GB8608818D0 (en) * | 1986-04-11 | 1986-05-14 | Reckitt & Colmann Prod Ltd | Pharmaceutical compositions |
| GB8629567D0 (en) * | 1986-12-10 | 1987-01-21 | Boots Co Plc | Therapeutic agents |
| US6348216B1 (en) * | 1996-06-10 | 2002-02-19 | Knoll Pharmaceutical Company | Ibuprofen and narcotic analgesic compositions |
| US6361794B1 (en) | 1996-06-12 | 2002-03-26 | Basf Corporation | Method of making ibuprofen and narcotic analgesic composition |
| DE19652188C2 (de) * | 1996-12-16 | 2002-02-14 | Lohmann Therapie Syst Lts | Flache Arzneizubereitung zur Applikation und Freisetzung von Buprenorphin oder einer pharmakologisch vergleichbaren Substanz in der Mundhöhle und Verfahren zu ihrer Herstellung |
| US6514929B1 (en) | 1998-11-25 | 2003-02-04 | The Procter & Gamble Company | Process for forming an agglomerated particle |
| US20030092724A1 (en) * | 2001-09-18 | 2003-05-15 | Huaihung Kao | Combination sustained release-immediate release oral dosage forms with an opioid analgesic and a non-opioid analgesic |
| WO2003061594A2 (en) * | 2002-01-23 | 2003-07-31 | The Regents Of The University Of California | Methods and compositions for reducing the development of drug tolerance and/or physical dependence |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4243673A (en) * | 1978-12-20 | 1981-01-06 | Ortho Pharmaceutical Corporation | Analgesic compositions and methods of use |
-
1979
- 1979-12-17 US US06/104,495 patent/US4315936A/en not_active Expired - Lifetime
-
1980
- 1980-11-28 NZ NZ195693A patent/NZ195693A/en unknown
- 1980-12-04 CA CA000366155A patent/CA1161758A/en not_active Expired
- 1980-12-15 JP JP17591780A patent/JPS5697225A/ja active Granted
- 1980-12-15 IL IL61714A patent/IL61714A/xx unknown
- 1980-12-15 ZA ZA00807851A patent/ZA807851B/xx unknown
- 1980-12-16 EP EP80304536A patent/EP0031234B1/en not_active Expired
- 1980-12-16 AU AU65409/80A patent/AU539193B2/en not_active Ceased
- 1980-12-16 IE IE2653/80A patent/IE50948B1/en not_active IP Right Cessation
- 1980-12-16 AT AT80304536T patent/ATE6470T1/de not_active IP Right Cessation
- 1980-12-16 DE DE8080304536T patent/DE3066887D1/de not_active Expired
-
1981
- 1981-05-29 US US06/265,297 patent/US4379789A/en not_active Expired - Lifetime
- 1981-07-24 PH PH25965A patent/PH16822A/en unknown
-
1984
- 1984-07-18 SG SG509/84A patent/SG50984G/en unknown
- 1984-11-25 HK HK805/84A patent/HK80584A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US4379789A (en) | 1983-04-12 |
| EP0031234A1 (en) | 1981-07-01 |
| EP0031234B1 (en) | 1984-03-07 |
| JPS6342605B2 (enExample) | 1988-08-24 |
| US4315936A (en) | 1982-02-16 |
| CA1161758A (en) | 1984-02-07 |
| ATE6470T1 (de) | 1984-03-15 |
| IE50948B1 (en) | 1986-08-20 |
| PH16822A (en) | 1984-03-06 |
| IE802653L (en) | 1981-06-17 |
| DE3066887D1 (en) | 1984-04-12 |
| HK80584A (en) | 1984-11-25 |
| SG50984G (en) | 1985-03-29 |
| ZA807851B (en) | 1982-07-28 |
| JPS5697225A (en) | 1981-08-05 |
| NZ195693A (en) | 1984-07-06 |
| AU6540980A (en) | 1981-06-25 |
| AU539193B2 (en) | 1984-09-13 |
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