IL61580A - Quinoline derivatives,the preparation of 1-(8-quinolyl)-2-pyrrolidinone and pharmaceutical compositions containing it - Google Patents

Quinoline derivatives,the preparation of 1-(8-quinolyl)-2-pyrrolidinone and pharmaceutical compositions containing it

Info

Publication number
IL61580A
IL61580A IL61580A IL6158080A IL61580A IL 61580 A IL61580 A IL 61580A IL 61580 A IL61580 A IL 61580A IL 6158080 A IL6158080 A IL 6158080A IL 61580 A IL61580 A IL 61580A
Authority
IL
Israel
Prior art keywords
pyrrolidinone
quinolyl
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL61580A
Other languages
English (en)
Other versions
IL61580A0 (en
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IL61580A0 publication Critical patent/IL61580A0/xx
Publication of IL61580A publication Critical patent/IL61580A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • C07D215/40Nitrogen atoms attached in position 8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL61580A 1979-11-30 1980-11-28 Quinoline derivatives,the preparation of 1-(8-quinolyl)-2-pyrrolidinone and pharmaceutical compositions containing it IL61580A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7941409 1979-11-30

Publications (2)

Publication Number Publication Date
IL61580A0 IL61580A0 (en) 1980-12-31
IL61580A true IL61580A (en) 1984-06-29

Family

ID=10509524

Family Applications (1)

Application Number Title Priority Date Filing Date
IL61580A IL61580A (en) 1979-11-30 1980-11-28 Quinoline derivatives,the preparation of 1-(8-quinolyl)-2-pyrrolidinone and pharmaceutical compositions containing it

Country Status (18)

Country Link
US (1) US4366158A (enExample)
EP (1) EP0030023A3 (enExample)
JP (1) JPS5699475A (enExample)
KR (1) KR830004293A (enExample)
AR (1) AR228442A1 (enExample)
AT (1) AT375363B (enExample)
AU (1) AU6495080A (enExample)
CA (1) CA1156235A (enExample)
DK (1) DK506480A (enExample)
ES (1) ES8203882A1 (enExample)
FI (1) FI803704L (enExample)
GB (1) GB2063868B (enExample)
GR (1) GR71918B (enExample)
HU (1) HU185224B (enExample)
IL (1) IL61580A (enExample)
IT (1) IT1221040B (enExample)
NZ (1) NZ195688A (enExample)
ZA (1) ZA807467B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1558582T3 (pl) 2003-07-22 2006-05-31 Arena Pharm Inc Diarylowe i aryloheteroarylowe pochodne mocznika jako modulatory receptora serotoninowego 5-HT2A użyteczne w profilaktyce i w leczeniu zaburzeń związanych z tym receptorem
GB0507198D0 (en) * 2005-04-08 2005-05-18 Sb Pharmco Inc Process for preparing bicyclic compounds
GB0519758D0 (en) * 2005-09-28 2005-11-09 Glaxo Group Ltd Novel process
US9084742B2 (en) 2007-12-12 2015-07-21 Axovant Sciences Ltd. Combinations comprising 3-phenylsulfonyl-8-piperazinyl-1yl-Quinoline
WO2009123714A2 (en) 2008-04-02 2009-10-08 Arena Pharmaceuticals, Inc. Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
WO2010062321A1 (en) 2008-10-28 2010-06-03 Arena Pharmaceuticals, Inc. Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2h-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)-urea and crystalline forms related thereto
MX388281B (es) 2015-06-12 2025-03-11 Axovant Sciences Gmbh Derivados de diaril y arilheteroaril urea como moduladores del receptor 5ht2a de serotonina útiles para la profilaxis y el tratamiento de un trastorno conductual del sueño rem.
CA2992518A1 (en) 2015-07-15 2017-01-19 Axovant Sciences Gmbh Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis and treatment of hallucinations associated with a neurodegenerative disease

Also Published As

Publication number Publication date
AT375363B (de) 1984-07-25
IT1221040B (it) 1990-06-21
IT8050277A0 (it) 1980-11-28
DK506480A (da) 1981-05-31
ES497242A0 (es) 1982-04-01
ES8203882A1 (es) 1982-04-01
GR71918B (enExample) 1983-08-17
AR228442A1 (es) 1983-03-15
FI803704A7 (fi) 1981-05-31
IL61580A0 (en) 1980-12-31
HU185224B (en) 1984-12-28
EP0030023A3 (en) 1981-09-02
KR830004293A (ko) 1983-07-09
ATA582780A (de) 1983-12-15
JPS5699475A (en) 1981-08-10
NZ195688A (en) 1984-09-28
EP0030023A2 (en) 1981-06-10
GB2063868A (en) 1981-06-10
FI803704L (fi) 1981-05-31
US4366158A (en) 1982-12-28
CA1156235A (en) 1983-11-01
GB2063868B (en) 1984-02-29
AU6495080A (en) 1981-06-04
ZA807467B (en) 1982-07-28

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