IL57690A - Process for the production of n-cyano-n'-methyl-n"-(2-((5-methyl-4-imidazolyl)methylthio)ethyl)guanidine - Google Patents

Process for the production of n-cyano-n'-methyl-n"-(2-((5-methyl-4-imidazolyl)methylthio)ethyl)guanidine

Info

Publication number
IL57690A
IL57690A IL57690A IL5769076A IL57690A IL 57690 A IL57690 A IL 57690A IL 57690 A IL57690 A IL 57690A IL 5769076 A IL5769076 A IL 5769076A IL 57690 A IL57690 A IL 57690A
Authority
IL
Israel
Prior art keywords
methyl
give
production
guanidine
methylthio
Prior art date
Application number
IL57690A
Original Assignee
Smithkline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/690,476 external-priority patent/US4063023A/en
Application filed by Smithkline Corp filed Critical Smithkline Corp
Priority claimed from IL50147A external-priority patent/IL50147A/en
Publication of IL57690A publication Critical patent/IL57690A/en

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Claims (1)

1. CLAIMS A process for the production of guanidine which comprises reducing a ic acid ester of the formula wherein R is methyl and is lower using an alkali metal or calcium in liquid ammonia with an additional proton to give the intermediate of Formula wherein R is as defined which is reacted with cysteamine under reflux in acetic acid to give and reacting the latter with thiourea to give the desired A modification of the process of claim wherein the intermediate imidazol is added to a solution of carbonate to give which is dissolved in a suitable to which there is added to give the desired Process for the production of to whenever obtained by a process according to any of claims 1 to insufficientOCRQuality
IL57690A 1975-08-20 1976-07-27 Process for the production of n-cyano-n'-methyl-n"-(2-((5-methyl-4-imidazolyl)methylthio)ethyl)guanidine IL57690A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US60627075A 1975-08-20 1975-08-20
US05/690,476 US4063023A (en) 1975-08-20 1976-05-27 Process for preparing 4-(hydroxymethyl)imidazole compounds
IL50147A IL50147A (en) 1975-08-20 1976-07-27 Reduction process for the preparation of 4-(hydroxymethyl)imidazole derivatives

Publications (1)

Publication Number Publication Date
IL57690A true IL57690A (en) 1980-11-30

Family

ID=27270713

Family Applications (1)

Application Number Title Priority Date Filing Date
IL57690A IL57690A (en) 1975-08-20 1976-07-27 Process for the production of n-cyano-n'-methyl-n"-(2-((5-methyl-4-imidazolyl)methylthio)ethyl)guanidine

Country Status (1)

Country Link
IL (1) IL57690A (en)

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