IL55817A - 11-(1-piperazinyl)-pyrazino(2,3-b)(1,5)-benzoxazepines and-benzothiazepines,their production and pharmaceutical compositions containing them - Google Patents

11-(1-piperazinyl)-pyrazino(2,3-b)(1,5)-benzoxazepines and-benzothiazepines,their production and pharmaceutical compositions containing them

Info

Publication number
IL55817A
IL55817A IL7855817A IL5581778A IL55817A IL 55817 A IL55817 A IL 55817A IL 7855817 A IL7855817 A IL 7855817A IL 5581778 A IL5581778 A IL 5581778A IL 55817 A IL55817 A IL 55817A
Authority
IL
Israel
Prior art keywords
benzoxazepines
benzothiazepines
pyrazino
piperazinyl
production
Prior art date
Application number
IL7855817A
Other languages
English (en)
Other versions
IL55817A0 (en
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IL55817A0 publication Critical patent/IL55817A0/xx
Publication of IL55817A publication Critical patent/IL55817A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL7855817A 1977-10-31 1978-10-30 11-(1-piperazinyl)-pyrazino(2,3-b)(1,5)-benzoxazepines and-benzothiazepines,their production and pharmaceutical compositions containing them IL55817A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1321977 1977-10-31
CH628178 1978-06-08

Publications (2)

Publication Number Publication Date
IL55817A0 IL55817A0 (en) 1978-12-17
IL55817A true IL55817A (en) 1982-02-28

Family

ID=25699303

Family Applications (1)

Application Number Title Priority Date Filing Date
IL7855817A IL55817A (en) 1977-10-31 1978-10-30 11-(1-piperazinyl)-pyrazino(2,3-b)(1,5)-benzoxazepines and-benzothiazepines,their production and pharmaceutical compositions containing them

Country Status (14)

Country Link
EP (1) EP0003016B1 (xx)
JP (1) JPS5481300A (xx)
AT (1) AT372964B (xx)
AU (1) AU525262B2 (xx)
CA (1) CA1100131A (xx)
DE (1) DE2861482D1 (xx)
DK (1) DK470978A (xx)
ES (1) ES474677A1 (xx)
FI (1) FI63582C (xx)
IL (1) IL55817A (xx)
IT (1) IT7851496A0 (xx)
NZ (1) NZ188772A (xx)
PH (1) PH14056A (xx)
PT (1) PT68722A (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4404137A (en) * 1979-10-16 1983-09-13 Lilly Industries Limited Pyrazolo [3,4-b][1,5]benzodiazepine compounds
JPS57118589A (en) * 1980-06-12 1982-07-23 Ciba Geigy Ag Imidazobenzothiazepine, manufacture, pharmaceutical medicine containing same and use as medicine
DE3032994A1 (de) * 1980-09-02 1982-04-22 Dr. Karl Thomae Gmbh, 7950 Biberach Neue pyrazino-azepine, deren herstellung und diese sie enthaltende arzneimittel
US4431589A (en) * 1980-12-11 1984-02-14 Lilly House Benzodiazepine compounds and their use as pharmaceuticals
US4444688A (en) * 1981-05-11 1984-04-24 Ciba-Geigy Corporation Imidazobenzothiadiazepines
US4460508A (en) * 1981-12-07 1984-07-17 Ciba-Geigy Corporation 5-Diazacycloalkylimidazo[1,2-c][1,3]benzodiazepines
US4460587A (en) * 1981-12-07 1984-07-17 Ciba-Geigy Corporation 5-Diazacycloalkyl imidazo[1,2-c][1,3]benzodiazepines
US4459232A (en) * 1981-12-07 1984-07-10 Ciba-Geigy Corporation Imidazo[1,2-c][1,3]benzodiazepines
BE1004596A4 (fr) * 1990-09-26 1992-12-22 Therabel Res S A N V Derives de methylpiperazinoazepine, leur preparation et leur utilisation.
US5393752A (en) * 1992-05-26 1995-02-28 Therabel Research S.A./N.V. Methylpiperazinoazepine compounds, preparation and use thereof
US5602121A (en) * 1994-12-12 1997-02-11 Allelix Biopharmaceuticals, Inc. Alkyl-substituted compounds having dopamine receptor affinity
US5602120A (en) * 1994-12-12 1997-02-11 Allelix Biopharmaceuticals, Inc. Benzyl-substituted compounds having dopamine receptor affinity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1470367A1 (de) * 1964-04-21 1969-11-13 Thomae Gmbh Dr K Verfahren zur Herstellung von in 5-Stellung substituierten 5,6-Dihydro-6-oxopyrido[2,3-b][1,4]benzoxazepinen
GB1156781A (en) * 1965-04-07 1969-07-02 Lab U P S A New Heterocyclic Compounds
GB1292410A (en) * 1970-05-13 1972-10-11 Yoshitomi Pharmaceutical Thienobenzothiazepine derivatives

Also Published As

Publication number Publication date
PT68722A (fr) 1978-11-01
ATA775578A (de) 1983-04-15
IT7851496A0 (it) 1978-10-13
FI63582C (fi) 1983-07-11
ES474677A1 (es) 1979-10-16
PH14056A (en) 1980-12-29
AU525262B2 (en) 1982-10-28
DE2861482D1 (en) 1982-02-18
JPS5481300A (en) 1979-06-28
CA1100131A (en) 1981-04-28
IL55817A0 (en) 1978-12-17
EP0003016A1 (en) 1979-07-25
FI783223A (fi) 1979-05-01
EP0003016B1 (en) 1981-12-30
AU4118678A (en) 1980-05-08
AT372964B (de) 1983-12-12
NZ188772A (en) 1981-02-11
DK470978A (da) 1979-05-01
FI63582B (fi) 1983-03-31

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