IL55801A0 - Novel proline derivatives and homologues thereof,their production and pharmaceutical compositions containing them - Google Patents
Novel proline derivatives and homologues thereof,their production and pharmaceutical compositions containing themInfo
- Publication number
- IL55801A0 IL55801A0 IL7855801A IL5580178A IL55801A0 IL 55801 A0 IL55801 A0 IL 55801A0 IL 7855801 A IL7855801 A IL 7855801A IL 5580178 A IL5580178 A IL 5580178A IL 55801 A0 IL55801 A0 IL 55801A0
- Authority
- IL
- Israel
- Prior art keywords
- homologues
- production
- pharmaceutical compositions
- compositions containing
- proline derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1315377 | 1977-10-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL55801A0 true IL55801A0 (en) | 1978-12-17 |
Family
ID=4389793
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL7855801A IL55801A0 (en) | 1977-10-28 | 1978-10-26 | Novel proline derivatives and homologues thereof,their production and pharmaceutical compositions containing them |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4261895A (da) |
| JP (1) | JPS5481266A (da) |
| AU (1) | AU4113878A (da) |
| BE (1) | BE871574A (da) |
| DE (1) | DE2845499A1 (da) |
| DK (1) | DK467378A (da) |
| ES (1) | ES474562A1 (da) |
| FI (1) | FI783189A (da) |
| FR (1) | FR2407204A1 (da) |
| GB (1) | GB2006781A (da) |
| IL (1) | IL55801A0 (da) |
| IT (1) | IT7851510A0 (da) |
| NL (1) | NL7810595A (da) |
| PT (1) | PT68707A (da) |
| SE (1) | SE7810893L (da) |
| ZA (1) | ZA786081B (da) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4690937A (en) * | 1979-08-14 | 1987-09-01 | University Of Miami | Anti-hypertensive agents |
| ZA794723B (en) * | 1978-09-11 | 1980-08-27 | Univ Miami | Anti-hypertensive agents |
| JPS5829950B2 (ja) * | 1978-10-05 | 1983-06-25 | ウェルファイド株式会社 | 環状イミノカルボン酸誘導体およびその塩類 |
| US4483861A (en) * | 1978-10-31 | 1984-11-20 | Santen Pharmaceutical Co., Ltd. | Antihypertensive sulfur-containing compounds |
| CA1132985A (en) * | 1978-12-22 | 1982-10-05 | John Krapcho | Ketal and thioketal derivatives of mercaptoacyl prolines |
| US4288368A (en) * | 1979-07-30 | 1981-09-08 | E. R. Squibb & Sons, Inc. | Dithioacylproline derivatives |
| US4291040A (en) * | 1979-10-22 | 1981-09-22 | E. R. Squibb & Sons, Inc. | Mercaptoacyl derivatives of 4-disubstituted prolines and 4-substituted dehydroprolines |
| FR2487829A2 (fr) * | 1979-12-07 | 1982-02-05 | Science Union & Cie | Nouveaux imino acides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme |
| US4565819A (en) * | 1979-12-07 | 1986-01-21 | Adir | Substituted imino diacids, their preparation and pharmaceutical compositions which contain them |
| JPS5683483A (en) * | 1979-12-13 | 1981-07-08 | Santen Pharmaceut Co Ltd | Thiazolidine compound |
| US4350704A (en) | 1980-10-06 | 1982-09-21 | Warner-Lambert Company | Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids |
| US4344949A (en) | 1980-10-03 | 1982-08-17 | Warner-Lambert Company | Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids |
| US4532342A (en) * | 1981-02-20 | 1985-07-30 | Warner-Lambert Company | N-substituted amino acids as intermediates in the preparation of acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids |
| EP0060668B1 (en) * | 1981-03-12 | 1985-10-09 | Beecham Group Plc | N-carboxyalkyl dipeptide derivatives and pharmaceutical compositions thereof |
| US4552889A (en) * | 1983-06-09 | 1985-11-12 | Eli Lilly And Company | 3-Mercaptomethyl-2-oxo-1-pyrrolidine acetic acids and use for hypertension |
| JPH06740B2 (ja) * | 1984-08-16 | 1994-01-05 | 三菱レイヨン株式会社 | 光学活性カルボン酸アミドの製造法 |
| IT1226796B (it) * | 1988-07-15 | 1991-02-19 | Simes | Composizione farmaceutica utile per il trattamento di malattie cardiovascolari. |
| IL91581A (en) * | 1988-09-13 | 1993-07-08 | Sepracor Inc | Methods for preparing optically active captopril and its analogues |
| US5166361A (en) * | 1988-09-13 | 1992-11-24 | Sepracor, Inc. | Methods for preparing captopril and its analogues |
| IT1241415B (it) * | 1990-03-05 | 1994-01-14 | Yason Srl | Derivato dell'acido s-(2-tenoil)-tiolattico ad attivita' farmacologica |
| US20020042377A1 (en) * | 1995-06-07 | 2002-04-11 | Steiner Joseph P. | Rotamase enzyme activity inhibitors |
| US7056935B2 (en) | 1995-06-07 | 2006-06-06 | Gpi Nil Holdings, Inc. | Rotamase enzyme activity inhibitors |
| US20070086958A1 (en) * | 2005-10-14 | 2007-04-19 | Medafor, Incorporated | Formation of medically useful gels comprising microporous particles and methods of use |
| US20070087061A1 (en) * | 2005-10-14 | 2007-04-19 | Medafor, Incorporated | Method and composition for creating and/or activating a platelet-rich gel by contact with a porous particulate material, for use in wound care, tissue adhesion, or as a matrix for delivery of therapeutic components |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4046889A (en) * | 1976-02-13 | 1977-09-06 | E. R. Squibb & Sons, Inc. | Azetidine-2-carboxylic acid derivatives |
| US4108886A (en) * | 1977-03-11 | 1978-08-22 | E. R. Squibb & Sons, Inc. | Thiopropanoylamino acid derivatives |
| US4217458A (en) * | 1978-12-08 | 1980-08-12 | E. R. Squibb & Sons, Inc. | Acylmercaptoacyl derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids |
-
1978
- 1978-10-16 IT IT7851510A patent/IT7851510A0/it unknown
- 1978-10-19 DE DE19782845499 patent/DE2845499A1/de not_active Withdrawn
- 1978-10-19 SE SE7810893A patent/SE7810893L/xx unknown
- 1978-10-19 FR FR7829752A patent/FR2407204A1/fr not_active Withdrawn
- 1978-10-19 DK DK467378A patent/DK467378A/da unknown
- 1978-10-19 FI FI783189A patent/FI783189A/fi unknown
- 1978-10-23 US US05/953,565 patent/US4261895A/en not_active Expired - Lifetime
- 1978-10-24 GB GB7841769A patent/GB2006781A/en not_active Withdrawn
- 1978-10-24 NL NL7810595A patent/NL7810595A/xx not_active Application Discontinuation
- 1978-10-26 IL IL7855801A patent/IL55801A0/xx unknown
- 1978-10-26 PT PT68707A patent/PT68707A/pt unknown
- 1978-10-26 BE BE191376A patent/BE871574A/xx unknown
- 1978-10-26 ES ES474562A patent/ES474562A1/es not_active Expired
- 1978-10-27 ZA ZA786081A patent/ZA786081B/xx unknown
- 1978-10-27 JP JP13173978A patent/JPS5481266A/ja active Pending
- 1978-10-27 AU AU41138/78A patent/AU4113878A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2407204A1 (fr) | 1979-05-25 |
| IT7851510A0 (it) | 1978-10-16 |
| DK467378A (da) | 1979-04-29 |
| GB2006781A (en) | 1979-05-10 |
| SE7810893L (sv) | 1979-04-29 |
| DE2845499A1 (de) | 1979-05-03 |
| PT68707A (fr) | 1978-11-01 |
| BE871574A (fr) | 1979-04-26 |
| JPS5481266A (en) | 1979-06-28 |
| FI783189A (fi) | 1979-04-29 |
| ES474562A1 (es) | 1979-10-16 |
| US4261895A (en) | 1981-04-14 |
| AU4113878A (en) | 1980-05-01 |
| ZA786081B (en) | 1980-06-25 |
| NL7810595A (nl) | 1979-05-02 |
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