IL52072A - 4-(or5)-(3-(substituted amino)-2-hydroxypropoxy)-spiro cycloalkane indanone or naphthone derivatives,their preparation and pharmaceutical compositions coprising them - Google Patents
4-(or5)-(3-(substituted amino)-2-hydroxypropoxy)-spiro cycloalkane indanone or naphthone derivatives,their preparation and pharmaceutical compositions coprising themInfo
- Publication number
- IL52072A IL52072A IL52072A IL5207277A IL52072A IL 52072 A IL52072 A IL 52072A IL 52072 A IL52072 A IL 52072A IL 5207277 A IL5207277 A IL 5207277A IL 52072 A IL52072 A IL 52072A
- Authority
- IL
- Israel
- Prior art keywords
- coprising
- naphthone
- indanone
- hydroxypropoxy
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
- C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
- C07C217/38—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system containing rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/93—Spiro compounds
- C07C2603/94—Spiro compounds containing "free" spiro atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH606376A CH621330A5 (no) | 1976-05-14 | 1976-05-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL52072A0 IL52072A0 (en) | 1977-07-31 |
| IL52072A true IL52072A (en) | 1980-10-26 |
Family
ID=4303639
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL52072A IL52072A (en) | 1976-05-14 | 1977-05-12 | 4-(or5)-(3-(substituted amino)-2-hydroxypropoxy)-spiro cycloalkane indanone or naphthone derivatives,their preparation and pharmaceutical compositions coprising them |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US4322437A (no) |
| JP (1) | JPS52139051A (no) |
| AT (1) | AT362349B (no) |
| AU (1) | AU513066B2 (no) |
| BE (1) | BE854567A (no) |
| CA (1) | CA1095913A (no) |
| CH (1) | CH621330A5 (no) |
| CY (1) | CY1226A (no) |
| DE (1) | DE2719871A1 (no) |
| DK (1) | DK197677A (no) |
| ES (1) | ES458724A1 (no) |
| FI (1) | FI771427A (no) |
| FR (1) | FR2351091A1 (no) |
| GB (1) | GB1576034A (no) |
| HK (1) | HK35984A (no) |
| IE (1) | IE44950B1 (no) |
| IL (1) | IL52072A (no) |
| KE (1) | KE3405A (no) |
| NL (1) | NL7705128A (no) |
| NZ (1) | NZ184079A (no) |
| PH (1) | PH14176A (no) |
| PT (1) | PT66540B (no) |
| SE (1) | SE7705221L (no) |
| SG (1) | SG84983G (no) |
| SU (1) | SU634663A3 (no) |
| ZA (1) | ZA772873B (no) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2810869A1 (de) * | 1977-03-24 | 1978-09-28 | Sandoz Ag | 3-amino-2-hydroxypropoxy-derivate, ihre herstellung und verwendung |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2641152A (en) * | 1949-07-15 | 1953-06-09 | Herbert M Hise | Stringed musical instrument |
| GB1046001A (en) * | 1964-03-12 | 1966-10-19 | Ici Ltd | Propanolamine derivatives |
| US3839415A (en) * | 1965-10-22 | 1974-10-01 | Lilly Co Eli | 2-halo-1-(alkyl-1-(alkylamino)ethyl)vinyl benzoic acid esters and derivatives |
| US3641152A (en) * | 1968-09-23 | 1972-02-08 | Warner Lambert Pharmaceutical | 3 4-dihydronaphthalenoneoxy-2-hydroxy-propylamines |
| CH554314A (de) * | 1969-06-03 | 1974-09-30 | Sandoz Ag | Verfahren zur herstellung neuer fluorenone. |
| BE755071A (fr) * | 1969-09-17 | 1971-02-22 | Warner Lambert Pharmaceutical | Procede de resolution de la dl-5-/3-(terbutylamino)-2- hydroxy-propoxy/-3,4-dihydro-1(2h) naphtalenone |
-
1976
- 1976-05-14 CH CH606376A patent/CH621330A5/de not_active IP Right Cessation
-
1977
- 1977-05-04 DE DE19772719871 patent/DE2719871A1/de not_active Ceased
- 1977-05-05 FI FI771427A patent/FI771427A/fi not_active Application Discontinuation
- 1977-05-05 SE SE7705221A patent/SE7705221L/xx not_active Application Discontinuation
- 1977-05-05 DK DK197677A patent/DK197677A/da not_active Application Discontinuation
- 1977-05-10 US US05/795,439 patent/US4322437A/en not_active Expired - Lifetime
- 1977-05-10 CY CY1226A patent/CY1226A/xx unknown
- 1977-05-10 NL NL7705128A patent/NL7705128A/xx not_active Application Discontinuation
- 1977-05-10 GB GB19551/77A patent/GB1576034A/en not_active Expired
- 1977-05-12 NZ NZ184079A patent/NZ184079A/xx unknown
- 1977-05-12 ES ES77458724A patent/ES458724A1/es not_active Expired
- 1977-05-12 IL IL52072A patent/IL52072A/xx unknown
- 1977-05-12 CA CA278,293A patent/CA1095913A/en not_active Expired
- 1977-05-12 PT PT66540A patent/PT66540B/pt unknown
- 1977-05-12 FR FR7714506A patent/FR2351091A1/fr active Granted
- 1977-05-12 BE BE177524A patent/BE854567A/xx not_active IP Right Cessation
- 1977-05-12 IE IE971/77A patent/IE44950B1/en unknown
- 1977-05-13 ZA ZA00772873A patent/ZA772873B/xx unknown
- 1977-05-13 SU SU772480276A patent/SU634663A3/ru active
- 1977-05-13 AU AU25140/77A patent/AU513066B2/en not_active Expired
- 1977-05-13 PH PH19769A patent/PH14176A/en unknown
- 1977-05-13 AT AT343577A patent/AT362349B/de not_active IP Right Cessation
- 1977-05-13 JP JP5449177A patent/JPS52139051A/ja active Pending
-
1983
- 1983-12-29 SG SG849/83A patent/SG84983G/en unknown
-
1984
- 1984-04-19 KE KE3405A patent/KE3405A/xx unknown
- 1984-04-26 HK HK359/84A patent/HK35984A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US4322437A (en) | 1982-03-30 |
| KE3405A (en) | 1985-02-01 |
| FI771427A (no) | 1977-11-15 |
| NL7705128A (nl) | 1977-11-16 |
| ES458724A1 (es) | 1978-08-01 |
| PT66540A (fr) | 1977-06-01 |
| IL52072A0 (en) | 1977-07-31 |
| DK197677A (da) | 1977-11-15 |
| FR2351091A1 (fr) | 1977-12-09 |
| SU634663A3 (ru) | 1978-11-25 |
| IE44950B1 (en) | 1982-05-19 |
| SE7705221L (sv) | 1977-11-15 |
| NZ184079A (en) | 1978-09-25 |
| CY1226A (en) | 1984-04-06 |
| SG84983G (en) | 1985-01-11 |
| AU513066B2 (en) | 1980-11-13 |
| ZA772873B (en) | 1978-12-27 |
| CA1095913A (en) | 1981-02-17 |
| IE44950L (en) | 1977-11-14 |
| JPS52139051A (en) | 1977-11-19 |
| PT66540B (fr) | 1979-10-22 |
| GB1576034A (en) | 1980-10-01 |
| AU2514077A (en) | 1978-11-16 |
| CH621330A5 (no) | 1981-01-30 |
| AT362349B (de) | 1981-05-11 |
| FR2351091B1 (no) | 1980-01-18 |
| BE854567A (fr) | 1977-11-14 |
| ATA343577A (de) | 1980-10-15 |
| PH14176A (en) | 1981-03-19 |
| HK35984A (en) | 1984-05-04 |
| DE2719871A1 (de) | 1977-12-01 |
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