IL51974A - 1-(2,3-dihydro-1,4-benzodioxin-2-yl)2-(4((1h)-indol-3-yl)-piperidino)ethanol derivatives, process for preparing them and pharmaceutical compositions containing them - Google Patents
1-(2,3-dihydro-1,4-benzodioxin-2-yl)2-(4((1h)-indol-3-yl)-piperidino)ethanol derivatives, process for preparing them and pharmaceutical compositions containing themInfo
- Publication number
- IL51974A IL51974A IL51974A IL5197477A IL51974A IL 51974 A IL51974 A IL 51974A IL 51974 A IL51974 A IL 51974A IL 5197477 A IL5197477 A IL 5197477A IL 51974 A IL51974 A IL 51974A
- Authority
- IL
- Israel
- Prior art keywords
- benzodioxin
- piperidino
- indol
- dihydro
- preparing
- Prior art date
Links
- DKLVUWAIFNMPQM-UHFFFAOYSA-N 1-(2,3-dihydro-1,4-benzodioxin-3-yl)-2-[4-(1h-indol-3-yl)piperidin-1-yl]ethanol Chemical class C1OC2=CC=CC=C2OC1C(O)CN1CCC(C=2C3=CC=CC=C3NC=2)CC1 DKLVUWAIFNMPQM-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7612941A FR2349331A1 (fr) | 1976-04-30 | 1976-04-30 | Nouveaux derives de 2,3 dihydro a/4-(3-indolyl) 1-piperidinyl/methyl 1,4-benzodioxin-2-methanol, un procede pour leur preparation et leur application comme medicaments |
Publications (2)
Publication Number | Publication Date |
---|---|
IL51974A0 IL51974A0 (en) | 1977-06-30 |
IL51974A true IL51974A (en) | 1980-09-16 |
Family
ID=9172538
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL51974A IL51974A (en) | 1976-04-30 | 1977-04-29 | 1-(2,3-dihydro-1,4-benzodioxin-2-yl)2-(4((1h)-indol-3-yl)-piperidino)ethanol derivatives, process for preparing them and pharmaceutical compositions containing them |
Country Status (18)
Country | Link |
---|---|
US (1) | US4100291A (fr) |
JP (1) | JPS52133992A (fr) |
AU (1) | AU506408B2 (fr) |
BE (1) | BE854112A (fr) |
CA (1) | CA1095047A (fr) |
CH (1) | CH602711A5 (fr) |
DE (1) | DE2719294A1 (fr) |
DK (1) | DK187577A (fr) |
ES (1) | ES458309A1 (fr) |
FR (1) | FR2349331A1 (fr) |
GB (1) | GB1542361A (fr) |
HU (1) | HU172529B (fr) |
IL (1) | IL51974A (fr) |
LU (1) | LU77241A1 (fr) |
NL (1) | NL7704759A (fr) |
SE (1) | SE7704615L (fr) |
SU (1) | SU700063A3 (fr) |
ZA (1) | ZA772601B (fr) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2362628A1 (fr) * | 1976-08-26 | 1978-03-24 | Roussel Uclaf | Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments |
FR2420536A1 (fr) * | 1978-03-22 | 1979-10-19 | Roussel Uclaf | Nouveaux derives de 1,3-dihydro 3-/1-/2-(2,3-dihydro 1,4-benzodioxin-2-yl)2-hydroxyethyl/piperidin-4-yl/2h-indol-2-one, procede pour leur preparation et application comme medicaments |
FR2444678A2 (fr) * | 1978-12-22 | 1980-07-18 | Roussel Uclaf | Nouveau procede de preparation de derives du piperidyl-indole et de leurs sels |
DE3035403C2 (de) | 1980-09-19 | 1982-08-26 | Rütgerswerke AG, 6000 Frankfurt | Verfahren zur Herstellung von 5-Chlorindol |
FR2533924A1 (fr) * | 1982-10-05 | 1984-04-06 | Roussel Uclaf | Nouveaux derives du 4-(1h-indol-3-yl)a-methyl piperidine-1-ethanol, leurs sels, le procede de preparation, l'application a titre de medicaments et les compositions les renfermant |
IE58370B1 (en) * | 1985-04-10 | 1993-09-08 | Lundbeck & Co As H | Indole derivatives |
US4742057A (en) * | 1985-12-05 | 1988-05-03 | Fujisawa Pharmaceutical Co., Ltd. | Antiallergic thiazole compounds |
DK733788A (da) * | 1988-01-14 | 1989-07-15 | Fujisawa Pharmaceutical Co | Indolylpiperidinderivater og fremgangsmaade til fremstilling deraf |
DE4414113A1 (de) * | 1994-04-22 | 1995-10-26 | Merck Patent Gmbh | 3-Indolylpiperidine |
CN1166665C (zh) * | 1998-03-19 | 2004-09-15 | 日本农药株式会社 | 芳基哌啶衍生物及其用途 |
JP2009515833A (ja) * | 2005-10-24 | 2009-04-16 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 3−ピペリジン−4−イル−インドールorl−1受容体モジュレーター |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2193584B1 (fr) * | 1972-07-28 | 1975-08-08 | Roussel Uclaf | |
DE2322470A1 (de) * | 1973-05-04 | 1974-11-21 | Boehringer Sohn Ingelheim | Neue indolyl-piperidino-(bzw. 1,2,5,6tetrahydro-pyridyl-)butyrophenone und verfahren zu ihrer herstellung |
US3914238A (en) * | 1974-01-18 | 1975-10-21 | Janssen Pharmaceutica Nv | 4-Aryl-{60 -(1,4-benzodioxan-2-yl)-4-hydroxy-1-piperidineethanols |
US4039676A (en) * | 1975-06-23 | 1977-08-02 | Ciba-Geigy Corporation | 2-piperidinoalkyl-1,4-benzodioxans |
-
1976
- 1976-04-30 FR FR7612941A patent/FR2349331A1/fr active Granted
-
1977
- 1977-04-21 SE SE7704615A patent/SE7704615L/xx not_active Application Discontinuation
- 1977-04-28 US US05/791,927 patent/US4100291A/en not_active Expired - Lifetime
- 1977-04-28 SU SU772497909A patent/SU700063A3/ru active
- 1977-04-28 HU HU77RO00000925A patent/HU172529B/hu unknown
- 1977-04-28 JP JP4858977A patent/JPS52133992A/ja active Pending
- 1977-04-29 NL NL7704759A patent/NL7704759A/xx not_active Application Discontinuation
- 1977-04-29 AU AU24709/77A patent/AU506408B2/en not_active Expired
- 1977-04-29 DK DK187577A patent/DK187577A/da not_active Application Discontinuation
- 1977-04-29 DE DE19772719294 patent/DE2719294A1/de not_active Withdrawn
- 1977-04-29 ZA ZA00772601A patent/ZA772601B/xx unknown
- 1977-04-29 ES ES458309A patent/ES458309A1/es not_active Expired
- 1977-04-29 CH CH541077A patent/CH602711A5/xx not_active IP Right Cessation
- 1977-04-29 GB GB7718081A patent/GB1542361A/en not_active Expired
- 1977-04-29 CA CA277,417A patent/CA1095047A/fr not_active Expired
- 1977-04-29 BE BE177137A patent/BE854112A/fr unknown
- 1977-04-29 IL IL51974A patent/IL51974A/xx unknown
- 1977-05-03 LU LU77241A patent/LU77241A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
SE7704615L (sv) | 1977-10-31 |
CA1095047A (fr) | 1981-02-03 |
BE854112A (fr) | 1977-10-31 |
JPS52133992A (en) | 1977-11-09 |
FR2349331B1 (fr) | 1978-08-25 |
AU506408B2 (en) | 1980-01-03 |
US4100291A (en) | 1978-07-11 |
SU700063A3 (ru) | 1979-11-25 |
HU172529B (hu) | 1978-09-28 |
ES458309A1 (es) | 1978-02-16 |
FR2349331A1 (fr) | 1977-11-25 |
DK187577A (da) | 1977-10-31 |
DE2719294A1 (de) | 1977-11-17 |
CH602711A5 (fr) | 1978-07-31 |
LU77241A1 (fr) | 1977-12-13 |
AU2470977A (en) | 1978-11-02 |
GB1542361A (en) | 1979-03-14 |
ZA772601B (en) | 1978-09-27 |
IL51974A0 (en) | 1977-06-30 |
NL7704759A (nl) | 1977-11-01 |
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