IL50874A - S-(6-(n'-methylthioureido)alkyl)and s(5-(n'-cyano-n"-methylguanidino)alkyl)isothiourea derivatives,process for their preparation and pharmaceutical compositions containing them - Google Patents
S-(6-(n'-methylthioureido)alkyl)and s(5-(n'-cyano-n"-methylguanidino)alkyl)isothiourea derivatives,process for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL50874A IL50874A IL50874A IL5087476A IL50874A IL 50874 A IL50874 A IL 50874A IL 50874 A IL50874 A IL 50874A IL 5087476 A IL5087476 A IL 5087476A IL 50874 A IL50874 A IL 50874A
- Authority
- IL
- Israel
- Prior art keywords
- alkyl
- methylthioureido
- methylguanidino
- cyano
- preparation
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 title 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/96—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/30—Isothioureas
- C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB49248/75A GB1578219A (en) | 1975-12-01 | 1975-12-01 | Isothioureas |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL50874A0 IL50874A0 (en) | 1977-01-31 |
| IL50874A true IL50874A (en) | 1981-06-29 |
Family
ID=10451685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL50874A IL50874A (en) | 1975-12-01 | 1976-11-09 | S-(6-(n'-methylthioureido)alkyl)and s(5-(n'-cyano-n"-methylguanidino)alkyl)isothiourea derivatives,process for their preparation and pharmaceutical compositions containing them |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US4084001A (fi) |
| JP (1) | JPS5268128A (fi) |
| AT (1) | AT351559B (fi) |
| AU (1) | AU509662B2 (fi) |
| BE (1) | BE848909A (fi) |
| CA (1) | CA1083171A (fi) |
| CH (1) | CH624387A5 (fi) |
| DE (1) | DE2654515A1 (fi) |
| DK (1) | DK517476A (fi) |
| ES (1) | ES453801A1 (fi) |
| FI (1) | FI64800C (fi) |
| FR (1) | FR2375206A1 (fi) |
| GB (1) | GB1578219A (fi) |
| HU (1) | HU176328B (fi) |
| IE (1) | IE44358B1 (fi) |
| IL (1) | IL50874A (fi) |
| LU (1) | LU76285A1 (fi) |
| NL (1) | NL7613093A (fi) |
| NO (1) | NO142525C (fi) |
| PT (1) | PT65839B (fi) |
| SE (1) | SE7613382L (fi) |
| ZA (1) | ZA766778B (fi) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4158013A (en) * | 1977-06-03 | 1979-06-12 | Bristol-Myers Company | N-Cyano-N'-alkynyl-N"-2-mercaptoethylguanidines |
| US4157340A (en) * | 1978-06-27 | 1979-06-05 | Bristol-Meyers Company | N,N'-[Bis(N-cyanoguanyl)]cystamine derivatives |
| ZA793392B (en) * | 1978-07-15 | 1980-08-27 | Smith Kline French Lab | Isoureas and isothioureas |
| DE3431923A1 (de) * | 1984-08-30 | 1986-03-13 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von sulvonyliso(thio)harnstoffen |
| US7115620B2 (en) | 2001-10-30 | 2006-10-03 | Wyeth | 1,3-disubstituted-2-thioxo-imidazolidine-4,5-diones as potassium channel openers |
| US7135492B2 (en) * | 2001-10-30 | 2006-11-14 | Wyeth | 1,3-disubstituted-2- thioxo-imidazolidine-4,5-dione derivatives useful in the treatment of atherosclerosis |
| WO2022034121A1 (en) | 2020-08-11 | 2022-02-17 | Université De Strasbourg | H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3669670A (en) * | 1970-12-02 | 1972-06-13 | Eastman Kodak Co | Photographic compositions containing bis-isothiuronium compounds as development activators and image stabilizers |
-
1975
- 1975-12-01 GB GB49248/75A patent/GB1578219A/en not_active Expired
-
1976
- 1976-11-09 IL IL50874A patent/IL50874A/xx unknown
- 1976-11-11 ZA ZA766778A patent/ZA766778B/xx unknown
- 1976-11-15 PT PT65839A patent/PT65839B/pt unknown
- 1976-11-17 DK DK517476A patent/DK517476A/da not_active Application Discontinuation
- 1976-11-23 US US05/744,584 patent/US4084001A/en not_active Expired - Lifetime
- 1976-11-24 NL NL7613093A patent/NL7613093A/xx not_active Application Discontinuation
- 1976-11-25 JP JP51142102A patent/JPS5268128A/ja active Pending
- 1976-11-25 AT AT875176A patent/AT351559B/de not_active IP Right Cessation
- 1976-11-26 CH CH1493776A patent/CH624387A5/de not_active IP Right Cessation
- 1976-11-29 CA CA266,796A patent/CA1083171A/en not_active Expired
- 1976-11-29 LU LU76285A patent/LU76285A1/xx unknown
- 1976-11-29 HU HU76SI1553A patent/HU176328B/hu unknown
- 1976-11-30 BE BE172841A patent/BE848909A/xx not_active IP Right Cessation
- 1976-11-30 SE SE7613382A patent/SE7613382L/xx not_active Application Discontinuation
- 1976-11-30 NO NO764084A patent/NO142525C/no unknown
- 1976-11-30 ES ES453801A patent/ES453801A1/es not_active Expired
- 1976-12-01 FI FI763458A patent/FI64800C/fi not_active IP Right Cessation
- 1976-12-01 AU AU20153/76A patent/AU509662B2/en not_active Expired
- 1976-12-01 FR FR7636265A patent/FR2375206A1/fr active Granted
- 1976-12-01 IE IE2635/76A patent/IE44358B1/en unknown
- 1976-12-01 DE DE19762654515 patent/DE2654515A1/de not_active Withdrawn
-
1978
- 1978-08-10 US US05/933,254 patent/USRE30457E/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| IL50874A0 (en) | 1977-01-31 |
| HU176328B (en) | 1981-01-28 |
| LU76285A1 (fi) | 1977-05-20 |
| FI763458A (fi) | 1977-06-02 |
| FR2375206B1 (fi) | 1980-03-07 |
| IE44358L (en) | 1977-06-01 |
| NO142525C (no) | 1980-09-03 |
| NO142525B (no) | 1980-05-27 |
| IE44358B1 (en) | 1981-11-04 |
| DK517476A (da) | 1977-06-02 |
| CH624387A5 (fi) | 1981-07-31 |
| CA1083171A (en) | 1980-08-05 |
| ZA766778B (en) | 1977-10-26 |
| AT351559B (de) | 1979-08-10 |
| FI64800C (fi) | 1984-01-10 |
| NO764084L (fi) | 1977-06-02 |
| FI64800B (fi) | 1983-09-30 |
| NL7613093A (nl) | 1977-06-03 |
| PT65839B (en) | 1978-05-15 |
| SE7613382L (sv) | 1977-06-02 |
| PT65839A (en) | 1976-12-01 |
| GB1578219A (en) | 1980-11-05 |
| AU2015376A (en) | 1978-06-08 |
| DE2654515A1 (de) | 1977-06-02 |
| FR2375206A1 (fr) | 1978-07-21 |
| USRE30457E (en) | 1980-12-23 |
| ATA875176A (de) | 1979-01-15 |
| BE848909A (fr) | 1977-05-31 |
| AU509662B2 (en) | 1980-05-22 |
| US4084001A (en) | 1978-04-11 |
| ES453801A1 (es) | 1977-11-01 |
| JPS5268128A (en) | 1977-06-06 |
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