IL49828A - 3-(halogen substituted 4-biphenylyl(or 4-phenoxy-phenyl))-3-hydroxyalkine derivatives,process for their preparation and pharmaceutical compositions containing them - Google Patents

3-(halogen substituted 4-biphenylyl(or 4-phenoxy-phenyl))-3-hydroxyalkine derivatives,process for their preparation and pharmaceutical compositions containing them

Info

Publication number
IL49828A
IL49828A IL49828A IL4982876A IL49828A IL 49828 A IL49828 A IL 49828A IL 49828 A IL49828 A IL 49828A IL 4982876 A IL4982876 A IL 4982876A IL 49828 A IL49828 A IL 49828A
Authority
IL
Israel
Prior art keywords
hydroxyalkine
biphenylyl
phenoxy
phenyl
derivatives
Prior art date
Application number
IL49828A
Other languages
English (en)
Other versions
IL49828A0 (en
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of IL49828A0 publication Critical patent/IL49828A0/xx
Publication of IL49828A publication Critical patent/IL49828A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/42Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing triple carbon-to-carbon bonds, e.g. with metal-alkynes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/12Acetic acid esters
    • C07C69/14Acetic acid esters of monohydroxylic compounds
    • C07C69/145Acetic acid esters of monohydroxylic compounds of unsaturated alcohols
    • C07C69/157Acetic acid esters of monohydroxylic compounds of unsaturated alcohols containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/62Halogen-containing esters
    • C07C69/63Halogen-containing esters of saturated acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/005Compounds containing elements of Groups 1 or 11 of the Periodic Table without C-Metal linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IL49828A 1975-06-19 1976-06-17 3-(halogen substituted 4-biphenylyl(or 4-phenoxy-phenyl))-3-hydroxyalkine derivatives,process for their preparation and pharmaceutical compositions containing them IL49828A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752527352 DE2527352A1 (de) 1975-06-19 1975-06-19 Alkin-derivate und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
IL49828A0 IL49828A0 (en) 1976-08-31
IL49828A true IL49828A (en) 1981-06-29

Family

ID=5949449

Family Applications (1)

Application Number Title Priority Date Filing Date
IL49828A IL49828A (en) 1975-06-19 1976-06-17 3-(halogen substituted 4-biphenylyl(or 4-phenoxy-phenyl))-3-hydroxyalkine derivatives,process for their preparation and pharmaceutical compositions containing them

Country Status (22)

Country Link
US (1) US4115456A (de)
JP (1) JPS523028A (de)
AT (1) AT354427B (de)
AU (1) AU499802B2 (de)
BE (1) BE843104A (de)
CA (1) CA1092147A (de)
CS (1) CS199204B2 (de)
DE (1) DE2527352A1 (de)
DK (1) DK272376A (de)
ES (1) ES448989A1 (de)
FR (1) FR2314709A1 (de)
GB (1) GB1498377A (de)
HK (1) HK24680A (de)
HU (1) HU176563B (de)
IE (1) IE43121B1 (de)
IL (1) IL49828A (de)
IT (1) IT7948303A0 (de)
LU (1) LU75182A1 (de)
MY (1) MY8100057A (de)
NL (1) NL7606646A (de)
SE (1) SE7607021L (de)
ZA (1) ZA763626B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2756031A1 (de) * 1977-12-15 1979-06-28 Bayer Ag 1-halogen-1-propin-3-ole, verfahren zu ihrer herstellung sowie ihre verwendung als fungizide
DE2964800D1 (en) * 1978-06-27 1983-03-24 Ciba Geigy Ag Alpha-prop-1-ynyl-3-phenoxybenzyl alcohols, their preparation and use as intermediate products in the preparation of pesticides
US5229426A (en) * 1988-09-15 1993-07-20 Ciba-Geigy Corporation Ethers useful for controlling pests
ATE106378T1 (de) * 1988-09-15 1994-06-15 Ciba Geigy Ag Neue aether.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1307360A (en) * 1969-05-16 1973-02-21 Bdh Pharmaceuticals Ltd Substituted 17alpha-penta-1,3-diynyl steroids
BE792079A (fr) * 1971-12-01 1973-05-29 Sandoz Sa Nouveaux composes insatures, leur preparation et leur application commemedicaments
US3879449A (en) * 1974-03-04 1975-04-22 Sandoz Ag 1-Phenyl-4-hydroxy-1-buten-3-ones and esters thereof

Also Published As

Publication number Publication date
SE7607021L (sv) 1976-12-20
IE43121L (en) 1976-12-19
DE2527352A1 (de) 1976-12-30
HU176563B (en) 1981-03-28
CS199204B2 (en) 1980-07-31
JPS523028A (en) 1977-01-11
NL7606646A (nl) 1976-12-21
IT7948303A0 (it) 1979-03-12
FR2314709B1 (de) 1979-09-28
HK24680A (en) 1980-05-16
AT354427B (de) 1979-01-10
CA1092147A (en) 1980-12-23
IE43121B1 (en) 1980-12-17
IL49828A0 (en) 1976-08-31
LU75182A1 (de) 1978-01-18
US4115456A (en) 1978-09-19
GB1498377A (en) 1978-01-18
ATA446276A (de) 1979-06-15
ES448989A1 (es) 1977-07-01
DK272376A (da) 1976-12-20
AU499802B2 (en) 1979-05-03
ZA763626B (en) 1977-05-25
FR2314709A1 (fr) 1977-01-14
MY8100057A (en) 1981-12-31
BE843104A (nl) 1976-12-20
AU1502976A (en) 1977-12-22

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