IL48365A - 10,11-dihydro-3-carboxycypro-heptadine and its n-oxide, their preparation and pharmaceutical compositions comprising them - Google Patents

10,11-dihydro-3-carboxycypro-heptadine and its n-oxide, their preparation and pharmaceutical compositions comprising them

Info

Publication number
IL48365A
IL48365A IL48365A IL4836575A IL48365A IL 48365 A IL48365 A IL 48365A IL 48365 A IL48365 A IL 48365A IL 4836575 A IL4836575 A IL 4836575A IL 48365 A IL48365 A IL 48365A
Authority
IL
Israel
Prior art keywords
dihydro
oxide
preparation
pharmaceutical compositions
carboxycypro
Prior art date
Application number
IL48365A
Other versions
IL48365A0 (en
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of IL48365A0 publication Critical patent/IL48365A0/en
Publication of IL48365A publication Critical patent/IL48365A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Saccharide Compounds (AREA)

Abstract

10,11-Dihydro-3-carboxycyproheptadine and its esters, amides and N-oxide are disclosed to have pharmaceutical utility as appetite stimulants and as antihistaminic agents. Also disclosed are processes for the preparation of such compounds; pharmaceutical compositions comprising such, compounds; and methods of treatment comprising administering such compounds and compositions.
IL48365A 1974-11-11 1975-10-27 10,11-dihydro-3-carboxycypro-heptadine and its n-oxide, their preparation and pharmaceutical compositions comprising them IL48365A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52267674A 1974-11-11 1974-11-11
US56328575A 1975-03-28 1975-03-28

Publications (2)

Publication Number Publication Date
IL48365A0 IL48365A0 (en) 1975-12-31
IL48365A true IL48365A (en) 1978-10-31

Family

ID=27060901

Family Applications (1)

Application Number Title Priority Date Filing Date
IL48365A IL48365A (en) 1974-11-11 1975-10-27 10,11-dihydro-3-carboxycypro-heptadine and its n-oxide, their preparation and pharmaceutical compositions comprising them

Country Status (19)

Country Link
JP (1) JPS6011029B2 (en)
AR (1) AR211108A1 (en)
AT (1) AT352126B (en)
CA (1) CA1082177A (en)
CH (1) CH621114A5 (en)
DE (1) DE2550395C3 (en)
DK (1) DK474575A (en)
ES (1) ES442375A1 (en)
FI (1) FI59583C (en)
FR (1) FR2290203A1 (en)
IE (1) IE42220B1 (en)
IL (1) IL48365A (en)
LU (1) LU73771A1 (en)
NL (2) NL173398B (en)
NO (1) NO144422C (en)
NZ (1) NZ179080A (en)
PH (1) PH13443A (en)
SE (1) SE424990B (en)
YU (1) YU273475A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4195091A (en) * 1978-11-15 1980-03-25 Merck & Co., Inc. Appetite stimulating pyrrolo[2,1-b][3]benzazepines
US4412999A (en) * 1982-04-14 1983-11-01 Merck & Co., Inc. Anti-emetic esters of cyproheptadine-3-carboxylic acid and structurally related compounds
US5250681A (en) * 1988-06-02 1993-10-05 Ajinomoto Co., Inc. Piperidine derivatives and hypotensives containing the same

Also Published As

Publication number Publication date
ES442375A1 (en) 1977-08-16
NL7512384A (en) 1976-05-13
LU73771A1 (en) 1976-09-06
NL173398B (en) 1983-08-16
FI752920A (en) 1976-05-12
FI59583C (en) 1981-09-10
CH621114A5 (en) 1981-01-15
PH13443A (en) 1980-04-23
IE42220B1 (en) 1980-07-02
AU8605775A (en) 1977-05-05
NO144422B (en) 1981-05-18
JPS6011029B2 (en) 1985-03-22
FR2290203B1 (en) 1980-05-30
DE2550395B2 (en) 1978-11-30
CA1082177A (en) 1980-07-22
AT352126B (en) 1979-09-10
NO753562L (en) 1976-05-12
FI59583B (en) 1981-05-29
JPS5170769A (en) 1976-06-18
IE42220L (en) 1976-05-11
IL48365A0 (en) 1975-12-31
YU273475A (en) 1983-04-27
NL173398C (en)
SE424990B (en) 1982-08-23
DE2550395A1 (en) 1976-05-13
DK474575A (en) 1976-05-12
NZ179080A (en) 1978-07-10
FR2290203A1 (en) 1976-06-04
DE2550395C3 (en) 1979-08-09
AR211108A1 (en) 1977-10-31
NO144422C (en) 1981-08-26
SE7511792L (en) 1976-05-12
ATA843975A (en) 1979-02-15

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