IL45639A - Germicidal cleaning preparation based on iodophors - Google Patents

Description

GERMICIDAL CLEANING PREPARATION BASED ON lODOPHORS The present Invention relates to a novel germicidal cleaning based on The novel matter according to the invention is characterized in that it it ie in a solid state and has a germicidal activity and an outstanding detergent Other and further aspects of the present invention will become apparent There are various germicidal preparations based as on such for example those described in and in German Patents 551 and These contain considerable amounts of such as polyethylene glycol and other polyhydroxy The inclusion of these was considered According to the present invention there is provided a novel composition of matter devoid of such The composition of matter comprises a sulfosuccinate al cohol s succinate of flatty and this obviates the necessity for the inclusion of bulky extenders which are and presence of the sulfosuccinates succinates enhandes the detergent properties of the novel composition of matter and increases the germicidal properties of same due to the synergistic properties of this The novel solid composition of to the present invention comprises essentially a mixture of fatty preferably ROH type where designates an group of about 10 to carbon atoms sulfated fatty alcohols of the formula where designates an alkyl group of 10 to about carbon fatty acids of the formula where designates alkyl of about 8 to 20 carbon and or of fatty alcohols of the respective gonoral formulas and wherein R and R which may be identical or di each 1 2 represents an group or an alkoxylated l group of 8 to carbon and 3 to about 20 per cent by weight of a suitable such as undecoylum chloride imidazoline iodine or any other suitable organic iodine preparation of this Generally technical products are used in the manufacture of the novel of matter according to the and thus they contain about 3 to 10 per cent water by weighto suitable lodophors there may be mentioned iodine complexes such as the various with sur and especially surface active agents of the ionic The novel preparations are advantageously prepared by heating the various ingredients together at an elevated temperature ao as to obtain an intimate fluid or fluid cooling the mixture to a lower temperature so to remain still in a extrudable adding thereto the and easting or shaping by other means a desired such as stick or the Some of the preparations were initially heated to about cooled to about the iodine complex added of the desired shape and the the final as pH of the preparation advantageously adjusted to a pH the acid which ought to be in the range suited for The best pH about pH and this can be by the addition of suitable physiologically acceptable Various organic acids are suited for this so The fatty acids are ously par of the compositions of the present but these do form an imperative part Example 70 Parts by weight lauryl alcohol sulfate active 10 per cent heated to and mixed with 20 parts parts stearic The pH was adjusted to pH the addition of lactic acid 1 per cent by and parts was According to a preferred embodiment of the invention of the preparation is adjusted to an optimum pH as regards human The advantageously effected with A preparation was prepared from per eent by weight fatty alcohol sulfates and cetyl and this was with myrietyl After heating to mixture admixed with of its weight of technical grade The pH was adjusted by addition of aoid to pH cooled to and by weight of polyvinyl pyrrolidone iodine was added and was extruded in the form of soap The following given the form of a Table the of a number of preparations according to the present It ought to be clearly understood that the ingredients are not and that these may be varied certain limits without departing fom the scope and spirit of the present The various percentages are to be adjusted mutually and these depend also to a certain extent on degree of hardness of the The following preparations were prepared as set out above parts are by I I I I I I V V VI Sulfated fatty alcohols to 20 35 30 30 Saturated fatty alcohols to 18 15 5 7 20 Saturated fatty acids to 8 10 10 of fatty alcohols to 35 18 18 Succinate of alcohols 9 Iodo hor or 10 10 5 15 Water 5 8 8 8 6 compositions were containing a quantity of en organic acid as citric or 1actice adapted to adjust the pH to a value of about The novel germicidal preparations according to the present invention were tested as to their The tests carried out have shown for a preparation according to the present invention containing 10 per cent by weight Povidone Iodine lost only 6 per cent of the available iodine during a period of storage of at A liquid detergent available containing the same initial percentage of iodine lost 27 per oent available iodine at during 30 Comparative tests have shown the superiority of preparations according to the present invention as regards storage with other commercial preparations containing Povidone The pH of the preparations according to the present invention is an optimum as regards the activity of the It known that the bactericidal efficacy of iodine and o organic iodine preparations is increased when the A pH of below 6 is generally the activity being still better at a pH of about 5 or below this preparation according to the present invention has a pH in while the advantageous properties of a good soap are The preparations according to the peesent invention are not detrimentally by hard No ring0 is i the bathtub and no pitates are formed wit hard water o with salts such as magnesium or calcium The of the preparation according to the present invention can be adjusted to the desired value by the addition of various physiologically acceptable acids such as lactic a citric phosphoric tartaric acid and the the novel preparations according to the present Invention have a further namely the enhanced effect of the and of the organic In soaps containin organic iodine har water ca the formation of a precipitate and this impairs the antibacterial The novel compositions are not adversely affected by hard and the effect and the bacteriaidal of the organic iodine compound each other and a certain is Conventional soaps used in places are often the source of due to the fact that bacteria may survive the surface of such solid soap bars and infect subsequent The bactericidal effect of the novel preparations is that practically no enie microorganism survive on the surface of a preparation according to the This property is of special importance in the case of in military nurseries and other Testes A bar was prepared according to Example and a suspension to i ts of 6 staphylococci was applied surface which had been wetted with tap water 3 minutes 60 seconds a ter the application of the a swab was taken A control was carried out conventional toilet and over 1000 A suspension of about ae was to applied the palm of a human hand and spread The hand was washed soap during tvo minutes of scrubbing and rinsed with About 680 microorganisms were A parallel test with a bar of the novel preparation according to Example resulted in zero survival the insufficientOCRQuality

Claims (9)

WHAT IS CLAIMED ISI

1. · A germicidal composition of matter in solid £orm comprising in combination a mixture of sulfated fatty alcohols, saturated fatty alcohols, saturated fatty acids, sulfosueeinate and/or succinate of fatty alcohols and a suitable organic iodine complex (PVP-iodine or the like),

2. · A germicidal composition as claimed in claim 1» wherein the sulfated fatty alcohols eomprise from about 20 to 50 per cent by weight* the saturated fatty alcohols from 3 to 20 per cent by weight, the eulfosuccinate andor succinate of fatty aloohole from 15 to **3 per cent by weight and the organic iodine complex rom 2 to 20 per cent by weight*

3. · A germicidal composition as claimed in claim 1 or 2, wherein the sulfated fatty alcohols are of C-12 to C-26; the saturated fatty alcohols o G-l¾ to G-26 and the eulfosuccinate and/or succinate of fatty alcohols of 6-12 to G-2*

4. , A germicidal composition of matter as claimed in any of claims 1 to 3» wherein the succinate is a mono*sulfosuccinate, Aa disulfo-succinate^ a mono-succinate or di-succinate or a mixture of these*

5. · A germicidal composition of matter as claimed in any of claims 1 to 4» wherein the iodine complex is PVP-iodine (povidone- iodine) or undeeoylum chloride iodine or imidazoline-iodine*

6. » A germicidal composition as claimed in any of claims 1 to¾ wherein the iodine complex is in a somplex of a non-ionic detergent and of iodine, of the iodophor type,

7. * A germicidal composition of matter as claimed in any of

8. · Germicidal composifcione of matter in eemi-solid form, substantially as hereinbefore deticribed and with reference to any of the examples.

9. * A process for preparing germicidal semi-solid compositions of matter as defined in any of claims 1 to 8» which eompSr&ses melting together all the ingredients except the iodophor, cooling the mixture to about 50-65°C, adding havi ng the iodophor and extruding or casting the product j*f desired shape* 10, Process for the production of germicidal -e-Mfll-solid compositions substantially as hereinbefore described and with reference to any of the