IL45299A - 16-phenoxy-11a,15a-dihydroxy-17,18,19,20-tetranor-5-cis-13-transprostadienoic acid and prostadienol derivatives and prostadienol derivatives and processes for their preparation - Google Patents

16-phenoxy-11a,15a-dihydroxy-17,18,19,20-tetranor-5-cis-13-transprostadienoic acid and prostadienol derivatives and prostadienol derivatives and processes for their preparation

Info

Publication number
IL45299A
IL45299A IL45299A IL4529974A IL45299A IL 45299 A IL45299 A IL 45299A IL 45299 A IL45299 A IL 45299A IL 4529974 A IL4529974 A IL 4529974A IL 45299 A IL45299 A IL 45299A
Authority
IL
Israel
Prior art keywords
prostadienol
derivatives
tetranor
dihydroxy
phenoxy
Prior art date
Application number
IL45299A
Other languages
English (en)
Other versions
IL45299A0 (en
Original Assignee
Ici Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Ltd filed Critical Ici Ltd
Publication of IL45299A0 publication Critical patent/IL45299A0/xx
Publication of IL45299A publication Critical patent/IL45299A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL45299A 1973-08-02 1974-07-18 16-phenoxy-11a,15a-dihydroxy-17,18,19,20-tetranor-5-cis-13-transprostadienoic acid and prostadienol derivatives and prostadienol derivatives and processes for their preparation IL45299A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3669173A GB1451798A (en) 1973-08-02 1973-08-02 Prostanoic acid derivatives

Publications (2)

Publication Number Publication Date
IL45299A0 IL45299A0 (en) 1974-10-22
IL45299A true IL45299A (en) 1978-06-15

Family

ID=10390378

Family Applications (1)

Application Number Title Priority Date Filing Date
IL45299A IL45299A (en) 1973-08-02 1974-07-18 16-phenoxy-11a,15a-dihydroxy-17,18,19,20-tetranor-5-cis-13-transprostadienoic acid and prostadienol derivatives and prostadienol derivatives and processes for their preparation

Country Status (24)

Country Link
US (1) US3954881A (cs)
JP (1) JPS5069045A (cs)
AR (1) AR204013A1 (cs)
AT (1) AT341119B (cs)
BE (1) BE818396A (cs)
CH (1) CH605511A5 (cs)
CS (1) CS174785B2 (cs)
DD (1) DD114401A5 (cs)
DE (1) DE2437388A1 (cs)
DK (1) DK410174A (cs)
EG (1) EG11489A (cs)
ES (1) ES428889A1 (cs)
FI (1) FI232274A7 (cs)
FR (1) FR2239995B1 (cs)
GB (1) GB1451798A (cs)
IE (1) IE40157B1 (cs)
IL (1) IL45299A (cs)
IN (1) IN138940B (cs)
LU (1) LU70639A1 (cs)
NL (1) NL7410343A (cs)
NO (1) NO742713L (cs)
SE (1) SE7409930L (cs)
ZA (1) ZA744509B (cs)
ZM (1) ZM12074A1 (cs)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1468830A (en) * 1974-01-26 1977-03-30 May & Baker Ltd Cyclopentane derivatives
US4183870A (en) * 1974-01-26 1980-01-15 May & Baker Limited Cyclopentane derivatives
GB1506816A (en) * 1975-03-31 1978-04-12 Upjohn Co Prostaglandins
NL7605381A (nl) * 1975-05-26 1976-11-30 Schering Ag Werkwijze voor het bereiden van prostaanderi- vaten en werkwijze voor het bereiden van een geneesmiddel met prostaglandinewerking.
US4388457A (en) * 1982-02-11 1983-06-14 University Patents, Inc. Phyllanthostatin compounds
GR1000519B (el) * 1989-03-28 1992-08-25 Abbott Lab Παραγωγα ερυθρομυκινης.
US5352708A (en) * 1992-09-21 1994-10-04 Allergan, Inc. Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5510383A (en) * 1993-08-03 1996-04-23 Alcon Laboratories, Inc. Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension
US6184250B1 (en) 1993-08-03 2001-02-06 Alcon Laboratories, Inc. Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
US5721273A (en) 1993-12-15 1998-02-24 Alcon Laboratories, Inc. Use of certain 9-halo-13,14-dihydroprostaglandins to treat glaucoma and ocular hypertension
WO1998034916A1 (fr) * 1997-02-10 1998-08-13 Ono Pharmaceutical Co., Ltd. Derives de 11,15-o-dialkylprostaglandine e, leur procede de production, et medicaments renfermant ceux-ci comme principe actif
MXPA04001831A (es) * 2001-08-29 2004-07-08 Neose Technologies Inc Nuevos derivados sinteticos de gangliosidos y composiciones de los mismos.
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
AU2004236174B2 (en) 2001-10-10 2011-06-02 Novo Nordisk A/S Glycopegylation methods and proteins/peptides produced by the methods
US9005625B2 (en) 2003-07-25 2015-04-14 Novo Nordisk A/S Antibody toxin conjugates
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
US20080300173A1 (en) 2004-07-13 2008-12-04 Defrees Shawn Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1]
SI2586456T1 (sl) 2004-10-29 2016-05-31 Ratiopharm Gmbh Preoblikovanje in glikopegliacija fibroblastnega rastnega faktorja (FGF)
WO2006052841A2 (en) * 2004-11-09 2006-05-18 Neose Technologies, Inc. Glycolipids
NZ556436A (en) 2005-01-10 2010-11-26 Biogenerix Ag Glycopegylated granulocyte colony stimulating factor
US9187546B2 (en) 2005-04-08 2015-11-17 Novo Nordisk A/S Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
WO2007056191A2 (en) 2005-11-03 2007-05-18 Neose Technologies, Inc. Nucleotide sugar purification using membranes
US20080274958A1 (en) 2006-07-21 2008-11-06 Neose Technologies, Inc. Glycosylation of peptides via o-linked glycosylation sequences
JP2010505874A (ja) 2006-10-03 2010-02-25 ノヴォ ノルディスク アー/エス ポリペプチドコンジュゲートの精製方法
RS52845B (en) 2007-04-03 2013-12-31 Biogenerix Ag Methods of treatment using glycopegylated g-csf
US9493499B2 (en) 2007-06-12 2016-11-15 Novo Nordisk A/S Process for the production of purified cytidinemonophosphate-sialic acid-polyalkylene oxide (CMP-SA-PEG) as modified nucleotide sugars via anion exchange chromatography
EP2626079A3 (en) 2008-02-27 2014-03-05 Novo Nordisk A/S Conjungated factor VIII molecules
US20120035120A1 (en) 2009-03-25 2012-02-09 Seneb Biosciences, Inc. Glycolipids as treatment for disease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1334952A (en) * 1971-01-06 1973-10-24 Ici Ltd Cyclopentane derivat-ves and a process for their manufacture

Also Published As

Publication number Publication date
NL7410343A (nl) 1975-02-04
ATA635674A (de) 1977-05-15
FR2239995A1 (cs) 1975-03-07
AR204013A1 (es) 1975-11-12
DE2437388A1 (de) 1975-02-13
BE818396A (fr) 1975-02-03
FI232274A7 (cs) 1975-02-03
LU70639A1 (cs) 1974-12-10
IN138940B (cs) 1976-04-17
CH605511A5 (cs) 1978-09-29
DK410174A (cs) 1975-04-01
US3954881A (en) 1976-05-04
CS174785B2 (cs) 1977-04-29
ES428889A1 (es) 1976-09-01
DD114401A5 (cs) 1975-08-05
IL45299A0 (en) 1974-10-22
ZA744509B (en) 1975-07-30
FR2239995B1 (cs) 1978-07-21
IE40157L (en) 1975-02-02
AT341119B (de) 1978-01-25
IE40157B1 (en) 1979-03-28
ZM12074A1 (en) 1976-11-22
EG11489A (en) 1978-06-30
GB1451798A (en) 1976-10-06
NO742713L (cs) 1975-03-03
SE7409930L (cs) 1975-02-03
AU7163574A (en) 1976-01-29
JPS5069045A (cs) 1975-06-09

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