IL44876A - 3-(imidazolin-2-yl 1,4,5,6-tetrahydro-pyrimidin-2-yl or 4,5,6,7-tetrahydro-1,3-diazepin-2-ylthio)-indole and 3-(1,4,5,6-tetrahydro-pyrimidinylthio)-7-aza-indole derivatives their production and pharmaceutical compositions containing them - Google Patents

3-(imidazolin-2-yl 1,4,5,6-tetrahydro-pyrimidin-2-yl or 4,5,6,7-tetrahydro-1,3-diazepin-2-ylthio)-indole and 3-(1,4,5,6-tetrahydro-pyrimidinylthio)-7-aza-indole derivatives their production and pharmaceutical compositions containing them

Info

Publication number
IL44876A
IL44876A IL44876A IL4487674A IL44876A IL 44876 A IL44876 A IL 44876A IL 44876 A IL44876 A IL 44876A IL 4487674 A IL4487674 A IL 4487674A IL 44876 A IL44876 A IL 44876A
Authority
IL
Israel
Prior art keywords
tetrahydro
indole
pyrimidinylthio
diazepin
ylthio
Prior art date
Application number
IL44876A
Other languages
English (en)
Other versions
IL44876A0 (en
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL44876A0 publication Critical patent/IL44876A0/xx
Publication of IL44876A publication Critical patent/IL44876A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D239/08—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
    • C07D239/10—Oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL44876A 1973-06-14 1974-05-21 3-(imidazolin-2-yl 1,4,5,6-tetrahydro-pyrimidin-2-yl or 4,5,6,7-tetrahydro-1,3-diazepin-2-ylthio)-indole and 3-(1,4,5,6-tetrahydro-pyrimidinylthio)-7-aza-indole derivatives their production and pharmaceutical compositions containing them IL44876A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH860973A CH574441A5 (de) 1973-06-14 1973-06-14

Publications (2)

Publication Number Publication Date
IL44876A0 IL44876A0 (en) 1974-07-31
IL44876A true IL44876A (en) 1978-01-31

Family

ID=4342576

Family Applications (1)

Application Number Title Priority Date Filing Date
IL44876A IL44876A (en) 1973-06-14 1974-05-21 3-(imidazolin-2-yl 1,4,5,6-tetrahydro-pyrimidin-2-yl or 4,5,6,7-tetrahydro-1,3-diazepin-2-ylthio)-indole and 3-(1,4,5,6-tetrahydro-pyrimidinylthio)-7-aza-indole derivatives their production and pharmaceutical compositions containing them

Country Status (17)

Country Link
US (1) US3954757A (de)
JP (1) JPS5849557B2 (de)
AT (1) AT333267B (de)
BE (1) BE816262A (de)
CH (1) CH574441A5 (de)
DD (1) DD112132A5 (de)
DE (1) DE2427207A1 (de)
DK (1) DK142701B (de)
ES (1) ES427269A1 (de)
FR (1) FR2233047B1 (de)
IE (1) IE39495B1 (de)
IL (1) IL44876A (de)
LU (1) LU70309A1 (de)
MC (1) MC1036A1 (de)
NL (1) NL7407614A (de)
SE (1) SE408709B (de)
YU (1) YU164774A (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5038759B2 (de) * 1971-12-20 1975-12-11
US4055647A (en) * 1973-06-14 1977-10-25 Ciba-Geigy Corporation Condensed pyrrole mercapto compounds having hypotensive and decongestant properties
BE503170A (de) * 1975-09-02
US3996218A (en) * 1975-09-08 1976-12-07 E. R. Squibb & Sons, Inc. Oxopyridazinylthiomethyl derivatives of ureidocephalosporins
US4171367A (en) * 1977-02-18 1979-10-16 Abbott Laboratories Pyrazolyl amino imidazolines
US5486525A (en) * 1993-12-16 1996-01-23 Abbott Laboratories Platelet activating factor antagonists: imidazopyridine indoles
US7582651B2 (en) * 2002-07-11 2009-09-01 Takeda Pharmaceutical Company Limited Pyrrolopyridine derivative and use thereof
EP2566481A4 (de) * 2010-05-06 2014-01-22 Merck Sharp & Dohme Als faah-modulatoren geeignete aza-indol-derivate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1141949A (en) * 1966-02-23 1969-02-05 Sterling Drug Inc 7-azaindole derivatives
US3377247A (en) * 1967-04-28 1968-04-09 Dow Chemical Co Antidepressant method
US3586695A (en) * 1968-01-26 1971-06-22 Dow Chemical Co Substituted imidazolinyl indoles

Also Published As

Publication number Publication date
ES427269A1 (es) 1976-07-01
NL7407614A (de) 1974-12-17
AT333267B (de) 1976-11-10
IE39495B1 (en) 1978-10-25
DD112132A5 (de) 1975-03-20
IL44876A0 (en) 1974-07-31
DK142701C (de) 1981-09-21
JPS5035160A (de) 1975-04-03
SE408709B (sv) 1979-07-02
FR2233047A1 (de) 1975-01-10
MC1036A1 (fr) 1975-05-30
YU164774A (en) 1982-08-31
DE2427207A1 (de) 1975-01-09
JPS5849557B2 (ja) 1983-11-05
IE39495L (en) 1974-12-14
LU70309A1 (de) 1976-04-13
ATA484774A (de) 1976-03-15
DK316674A (de) 1975-02-17
DK142701B (da) 1980-12-22
SE7407175L (de) 1974-12-16
CH574441A5 (de) 1976-04-15
FR2233047B1 (de) 1977-11-04
BE816262A (fr) 1974-12-13
US3954757A (en) 1976-05-04

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