IL43955A0 - Novel 1,4-benzodioxane derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Novel 1,4-benzodioxane derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL43955A0
IL43955A0 IL43955A IL4395574A IL43955A0 IL 43955 A0 IL43955 A0 IL 43955A0 IL 43955 A IL43955 A IL 43955A IL 4395574 A IL4395574 A IL 4395574A IL 43955 A0 IL43955 A0 IL 43955A0
Authority
IL
Israel
Prior art keywords
novel
preparation
pharmaceutical compositions
compositions containing
benzodioxane derivatives
Prior art date
Application number
IL43955A
Other languages
English (en)
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of IL43955A0 publication Critical patent/IL43955A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/02—Preparation by ring-closure or hydrogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL43955A 1973-01-04 1974-01-03 Novel 1,4-benzodioxane derivatives,their preparation and pharmaceutical compositions containing them IL43955A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32105873A 1973-01-04 1973-01-04
US417702A US3910930A (en) 1973-01-04 1973-11-20 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones

Publications (1)

Publication Number Publication Date
IL43955A0 true IL43955A0 (en) 1974-05-16

Family

ID=26982795

Family Applications (1)

Application Number Title Priority Date Filing Date
IL43955A IL43955A0 (en) 1973-01-04 1974-01-03 Novel 1,4-benzodioxane derivatives,their preparation and pharmaceutical compositions containing them

Country Status (8)

Country Link
US (1) US3910930A (fr)
JP (1) JPS4995980A (fr)
AU (1) AU6418474A (fr)
BE (1) BE809410A (fr)
DE (1) DE2400094A1 (fr)
FR (1) FR2213059B1 (fr)
IL (1) IL43955A0 (fr)
NL (1) NL7400132A (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3996362A (en) * 1975-05-28 1976-12-07 E. R. Squibb & Sons, Inc. 2-[[4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-(piperidinyl or 1,2,3,6-tetrahydro-1-pyridinyl)]alkyl]-1H-benz[de]isoquinoline-1,3(2H)-diones
GB1582239A (en) * 1976-12-11 1981-01-07 Wyeth John & Brother Ltd Piperidin-4-yl ureas and thioureas
GR71865B (fr) * 1978-03-20 1983-07-07 Ciba Geigy
FR2420536A1 (fr) * 1978-03-22 1979-10-19 Roussel Uclaf Nouveaux derives de 1,3-dihydro 3-/1-/2-(2,3-dihydro 1,4-benzodioxin-2-yl)2-hydroxyethyl/piperidin-4-yl/2h-indol-2-one, procede pour leur preparation et application comme medicaments
US4181802A (en) * 1978-05-11 1980-01-01 Janssen Pharmaceutica N.V. 1-(Heterocyclylalkyl)-1,3-dihydro-2-H-benzimidazole-2-ones
JPS54160371A (en) * 1978-06-02 1979-12-19 Kyowa Hakko Kogyo Co Ltd Novel piperidine derivative and hypotensive agents comprising it
GR69650B (fr) * 1978-07-20 1982-07-07 Science Union & Cie
US4329348A (en) * 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants
JPS5668680A (en) * 1979-11-06 1981-06-09 Kyowa Hakko Kogyo Co Ltd Novel piperidine derivative and hypotensive agent containing the same
FR2469411A1 (fr) * 1979-11-15 1981-05-22 Science Union & Cie Nouveaux derives de la piperidylbenzimidazolinone, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
PL128510B1 (en) * 1980-03-01 1984-02-29 Wyeth John & Brother Ltd Method of obtaining new piperidine derivatives
FR2482101A1 (fr) * 1980-05-07 1981-11-13 Cerm Cent Europ Rech Mauvernay 2-methanol a-aminomethyl benzo (1,4) dioxines, leur procede de preparation et leur application en therapeutique
DE3124366A1 (de) * 1981-06-20 1982-12-30 Hoechst Ag, 6000 Frankfurt N-oxacyclyl-alkylpiperidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische praeparate und deren verwendung
FR2530632A1 (fr) * 1982-07-26 1984-01-27 Bouchara Emile Nouveaux derives substitues du 2,5-diamino 1,4-diazole, leurs procedes de preparation et les compositions pharmaceutiques en renfermant
US4569933A (en) * 1984-04-13 1986-02-11 Cornu Pierre Jean Antihypertensive substituted derivatives of 2,5-diamino 1,4-diazole
EP0300077B1 (fr) * 1987-07-23 1993-03-17 Mitsubishi Denki Kabushiki Kaisha Détecteur de surcharge
EP0367888A1 (fr) * 1988-11-08 1990-05-16 ISTITUTO LUSO FARMACO D'ITALIA S.p.A. Dérivés de 1,4-benzodioxine 2,2-disubstitués ayant une action hypotensive
FR2690158B1 (fr) * 1992-04-17 1994-07-22 Sanofi Elf Nouveau derive arylpiperidinique, procede pour sa preparation et compositions pharmaceutiques le contenant.
US6133277A (en) 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties
KR100699512B1 (ko) 1999-06-02 2007-03-26 얀센 파마슈티카 엔.브이. 아미노알킬 치환된 (벤조디옥산, 벤조푸란 또는 벤조피란)유도체
CA2374905C (fr) * 1999-06-02 2010-02-23 Janssen Pharmaceutica N.V. Derives de benzopyrane substitues par un pyrrolidinyle, un piperidinyle ou un homopiperidinyle permettant de traiter la relaxation fundique alteree
JO2352B1 (en) 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus
JO2654B1 (en) * 2000-09-04 2012-06-17 شركة جانسين فارماسوتيكا ان. في Multiple aryl caroxa amides are useful as lipid - lowering agents
JO2409B1 (en) * 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
CA2465328C (fr) * 2001-11-01 2011-06-14 Michael Francis Gross Piperidines
JP2009525269A (ja) * 2006-01-30 2009-07-09 ユーロ−セルティーク エス．エイ． カルシウムチャネルブロッカーとしての環状尿素化合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE633495A (fr) * 1962-06-13
US3238216A (en) * 1963-06-20 1966-03-01 Res Lab Dr C Janssen N V Substituted 1, 3, 8-triaza-spiro (4, 5) decanes
US3225052A (en) * 1964-05-06 1965-12-21 Janssen Pharmaceutica Nv Benzimidazolinyl piperidine derivatives
US3629267A (en) * 1968-10-28 1971-12-21 Smith Kline French Lab Benzoheterocyclicalkyl derivatives of 4-(2-keto -1-benzimidazolinyl)-piperidine 4-(2-keto - 1 - benzimidazolinyl) -1 2 3 6 tetrahydropyridine 1 - phenyl - 1 3 8-triazaspiro(4 5)decan - 4 - one and 2 4 9-triazaspiro(5 5)undecan-1 3 5-trione
JPS4920788B1 (fr) * 1970-08-19 1974-05-27

Also Published As

Publication number Publication date
BE809410A (nl) 1974-07-04
NL7400132A (fr) 1974-07-08
FR2213059A1 (fr) 1974-08-02
DE2400094A1 (de) 1974-07-18
AU6418474A (en) 1975-07-10
JPS4995980A (fr) 1974-09-11
US3910930A (en) 1975-10-07
FR2213059B1 (fr) 1977-09-09

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